› › A Primate Model For The Study Of Colitis And Colonic Carcinoma The Cotton Top Tamarin Saguinus Oedipus

A Primate Model for the Study of Colitis and Colonic Carcinoma The Cotton-Top Tamarin (Saguinus oedipus)

Author : Neal K. Clapp

Publisher : CRC Press

Page : 281 pages

File Size : 41,30 MB

Release : 2018-01-18

Category : Medical

ISBN : 1351086316

Get eBook

Book Description

A Primate Model for the Study of Colitis and Colonic Carcinoma describes recent observations of the prevalence, pathogenesis, natural history, and time-course of idiopathic colitis and colonic carcinoma in the Cotton-Top Tamarin (CTT) model. Results of colonoscopy and mucosal biopsy are shown to evaluate the therapeutic efficacy of new anti-colitic agents. The contributions of antigenic profiles as a function of disease state, occurrence of extra-intestinal manifestations, and possible causal agents of colitis are also discussed. Prevalence of spontaneous CTT colonic carcinoma is considered from genetic influence, from promotion by colitis, and through the use of diagnostic and prognostic tools such as flow cytometry. Changes in fecal steroids, serum markers, colonic glycoprotein, polyamine metabolism, and immunobiology of CTTs are discussed in regard to disease condition. The book is an essential reference on the CTT model for gastroenterologists, oncologists, and all researchers interested in digestive diseases.



Crohn's Disease

Author : Gary R. Lichtenstein

Publisher : CRC Press

Page : 1017 pages

File Size : 33,40 MB

Release : 2024-06-01

Category : Medical

ISBN : 1040142605

Get eBook

Book Description

Crohn’s Disease: The Complete Guide to Medical Management serves as the definitive source for medical management of Crohn’s Disease (CD). Dr. Gary R. Lichtenstein, along with Dr. Ellen J. Scherl, have collaborated with over 60 experts from around the world to provide gastroenterologists and those in training with the necessary information to successfully manage the patient with Crohn’s disease. Sections Include: • General o The role of the FDA in drug development; pediatric considerations; disease modifiers; and more • Medications o Antibiotic use in treatment of CD; oral budesonide; infliximab; novel biological and non biologic therapies for CD; and more • Specific Clinical Scenarios o Management of steroid unresponsive CD; management of enteric fistulae; use of pre- and probiotics; medical management of short bowel syndrome; maintenance therapy of CD; and more Features: • Color images, graphs, and tables • Extensive index that includes cross-referencing to Ulcerative Colitis: The Complete Guide to Medical Management • An appendix on Infliximab treatment • Comprehensive references at the end of each chapter Organized into an easy-to-reference format, Crohn’s Disease: The Complete Guide to Medical Management threads theory into practice and provides Gastroenterology professionals with the most comprehensive information available on this disease state. The other side of inflammatory bowel disease is covered in Drs. Gary R. Lichtenstein and Ellen J. Scherl’s Ulcerative Colitis: The Complete Guide to Medical Management. All gastroenterologists will find both books to be essential for future practice in the treatment and care of their patients with either Crohn’s disease or ulcerative colitis, as well as in the overall management of those with inflammatory bowel disease.



National Library of Medicine Current Catalog

Author : National Library of Medicine (U.S.)

Publisher :

Page : 690 pages

File Size : 10,91 MB

Release : 1993

Category : Medicine

ISBN :

Get eBook

Book Description

First multi-year cumulation covers six years: 1965-70.



New Perspectives in the Study of Mesoamerican Primates

Author : Alejandro Estrada

Publisher : Springer Science & Business Media

Page : 598 pages

File Size : 50,2 MB

Release : 2006-07-31

Category : Science

ISBN : 0387258728

Get eBook

Book Description

The purpose of this volume is to present a comprehensive overview of recent advances in primate field research, ecology, and conservation biology in Mesoamerica. The overall goal of each contribution is to integrate newly collected field data with theoretical perspectives drawn from evolutionary biology, socioecology, biological anthropology, and conservation to identify how our current knowledge of primate behavior and ecology has moved beyond more traditional approaches. A corollary to this, and an important goal of the volume is to identify geographical regions and species for which we continue to lack sufficient information, to develop action plans for future research, and to identify areas for immediate conservation action. Despite many decades of primate research in Mesoamerica, much is still unknown concerning the basic ecology and behavior of these species, demography, current distribution, and conservation status of local populations, and the effectiveness of conservation policies on primate survivorship. Four major areas of research are the focus of the volume: Evolutionary Biology and Biogeography; Population Demography and Ecology; Behavior; and Conservation and Management Policies.



Biological Models in Radiopharmaceutical Development

Author : R.M. Lambrecht

Publisher : Springer Science & Business Media

Page : 291 pages

File Size : 26,84 MB

Release : 2012-12-06

Category : Medical

ISBN : 9400901593

Get eBook

Book Description

Radiophannaceuticals labeled with short-lived radionuclides are utilized to unravel biochemical processes, and to diagnosis and treat diseases of the living body are-developed through extensive evaluation in ~iological models. 'fhC first attempt to compile information was a volume entitled ANIMAL MODELS IN RADIOTRACER DESIGN that was edited by William C. Eckelman and myself in 1983. The volume had a focus on the animal models that investigators were using in order to design radiotracers that displayed in vivo selectivity as measured by biodistribution and pharmacokinetic studies. A concern in the early days of nuclear medicine was species differences. Often a series of labeled compounds were evaluated in a several different animal models in order to gain confidence that the selected radiotracer would behave appropriately in humans. During the past 12 years there have been remarkable advances in molecular genetics, molecular biology, synthetic radiopharmaceutical chemistry, molecular modeling and visualization, and emission tomography. Biological models can now be selected that are better defined in terms of molecular aspects of the disease process. The development of high resolution PET and SPET for clinical applications facilitates the development of new radiopharmaceuticals by the use of models to quantitatively evaluate drug effects, and progression of disease, and hence to arrive at better diagnosis and treatments for animals and humans. With these advances there is an effective use of biological models, and the refinement of alternatives for the development of new radiophannaceuticals.



Medical Primatology

Author : Eman P Fridman

Publisher : CRC Press

Page : 396 pages

File Size : 25,16 MB

Release : 2002-03-14

Category : Medical

ISBN : 9780415275835

Get eBook

Book Description

Due to the high degree of biological similarity between primates and humans, monkeys and apes have been used successfully in medical research for many decades. Medical Primatology: History, Biological Foundations and Applications provides a comprehensive summary linking the use of monkeys and apes in biomedical research to their kinship with humans. The book begins by discussing the history of this research, and then focuses on the biological foundations upon which medical primatology has been built. Primate taxonomy and evolution are reviewed, using not only traditional sources of data, but also recent experimental evidence from molecular biology, genetics, and biomedicine that indicates the need to place higher simians in the family of man. Condensing a broad range of scientific literature into one volume, this will be a useful reference for specialists in the biological sciences and medicine, as well as researchers involved in biological, anthropological, biomedical, clinical, and pharmacological research on primates.



Ulcerative Colitis

Author : Gary R. Lichtenstein

Publisher : SLACK Incorporated

Page : 514 pages

File Size : 36,95 MB

Release : 2011

Category : Medical

ISBN : 1556429452

Get eBook

Book Description

Dr. Gary R. Lichtenstein, along with Dr. Ellen J. Scherl, have collaborated with over 60 experts from around the world to provide gastroenterologists and those in training with the necessary information to successfully manage the patient with ulcerative colitis. Organized into an easy-to-reference format this book threads theory into practice and provides gastroenterology professionals with the most comprehensive information available. The other side of inflammatory bowel disease is covered in Drs. Gary R. Lichtenstein and Ellen J. Scherl.s Crohn.s Disease: The Complete Guide to Medical Management. All gastroenterologists will find both books to be essential for future practice in the treatment and care of their patients with either Crohn.s disease or ulcerative colitis, as well as in the overall management of those with inflammatory bowel disease.





Nonhuman Primates in Biomedical Research

Author :

Publisher : Elsevier

Page : 525 pages

File Size : 15,55 MB

Release : 1998-07-24

Category : Science

ISBN : 0080537634

Get eBook

Book Description

This volume and its companion Nonhuman Primates in Biomedical Research: Biology and Management represent the most comprehensive publications of their type on nonhuman primates. This volume addresses the diseases of nonhuman primates with an emphasis on the etiological factors, clinical signs, diagnostic pathology, therapy, and management. Its companion volume serves as a general reference for those who provide care for these animals and for those who use them in biomedical research.