Pediatric Formulations


Book Description

Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.




Update in Pediatrics


Book Description

This concise and comprehensive volume updates health professionals on recent advances in the field of pediatrics. It includes chapters in every subspecialty of pediatrics, such as critical care, development emergency medicine and genetics. Ranging from traditional disciplines such as infectious disease and cardiology to more current disciplines such as adolescent medicine, metabolics and genetics this is an indispensable guide for the busy clinician who wishes to stay up-to date with latest advances in the field. Through the use of summaries and bullet points, the book conciselly describes the latest recommendations and guidelines in pediatrics and provides a good overview of the available technology for each subspecialty. The team of authors is made up of experienced clinicians and researchers in their respective fields. This book appeals to pediatricians, family doctors, nurses and nurse practitioners, allied health professionals, and health researchers.




Advances in Pediatrics, E-Book 2020


Book Description

Each year, Advances in Pediatrics focuses on providing current clinical information on important topics in pediatrics. Dr. Carol Berkowitz and her editorial board, comprised of top experts in the field, have assembled authors to provide updates on the following topics: Evaluation and Management of Febrile Infants; Pediatric Emergency Medicine and Ultrasonography; The Patient-Centered Pediatric Emergency Department; Health Considerations of Refuge and Immigrant Children; Management of scoliosis; Health and Wellness for LGBTQ Youth; Sexually exploited children: recognizing and addressing; Movement disorders in children; Childhood trauma management in primary care; Feeding issues in young children; Physician Well-being and Burnout; New Molecular Methods for Diagnosing Infectious Diseases; Parental refusal: treatments, procedures and vaccines; Pediatric oncology in the ICU setting; Diaphragmatic hernia: Management and Outcomes; and Global Health and Pediatric Education: Opportunities and Challenges. Readers will come away with the clinical information that supplements their professional knowledge so they can make informed clinical decisions that improve patient outcomes.




Advances in Pediatrics, 2024


Book Description

Advances in Pediatrics reviews the year's most important findings and updates within the field in order to provide pediatricians and primary care providers with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Carol Berkowitz, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in pediatrics inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care. Contains over 15 articles on such topics as Management of Congenital Adrenal Hyperplasia; Children and the US Juvenile Legal System; Novel Approaches to Patients with Differences of Sex Development; Pectus Disorders; Pediatric Immune Thrombocytopenia; and more. Provides in-depth, clinical reviews in pediatrics, providing actionable insights for clinical practice. Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.




Advances in Pediatrics, E-Book 2023


Book Description

Advances in Pediatrics reviews the year’s most important findings and updates within the field in order to provide pediatricians and primary care providers with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Carol Berkowitz, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in pediatrics inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care. Contains 16 articles on such topics as transgender medicine, effects of COVID on trauma and child abuse, preventing cardiac death in children, Munchhausen syndrome by proxy, appendicitis, and more. Provides in-depth, clinical reviews in pediatrics, providing actionable insights for clinical practice. Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.




Red Book 2021


Book Description

The AAP's authoritative guide on preventing, recognizing, and treating more than 200 childhood infectious diseases. Developed by the AAP's Committee on Infectious Diseases as well as the expertise of the CDC, the FDA, and hundreds of physician contributors.




2022 Nelson's Pediatric Antimicrobial Therapy


Book Description

Completely updated and revised, the 28th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children. For each disease, the authors provide a commentary to help select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens. TOPICS INCLUDE Antimicrobial Therapy by Clinical Syndromes Antimicrobial Therapy for Neonates Choosing Among Antibiotics Antifungal Agents Antiviral Agents Antiparasitic Agents Oral Step-down Therapy for Serious Infections Prevention of Symptomatic Infection Approach to Antibiotic Allergies Antibiotic Stewardship New in the 28th Edition Updated recommendations on acute hematogenous osteomyelitis, based on newly published guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America, including information on a decrease in the incidence of MRSA infections, allowing the recommendation of cefazolin, again, in empiric therapy for most pediatric bone infections Updated recommendations on influenza treatment and prophylaxis, reflecting American Academy of Pediatrics guidance for 2021-2022 Ceftazidime/avibactam now preferred over fluoroquinolones for treatment of Klebsiella pneumoniae carbapenemase-producing enteric bacilli, if susceptible Cefiderocol, a new iron-binding siderophore cephalosporin class, recently approved in adults for treatment of many drug-resistant pathogens, particularly Acinetobacter, Stenotrophomonas, and Pseudomonas; under study in children New dosing for posaconazole suspension formulation New approaches to mucormycosis Added baloxavir for children 12+ years old Online updates of COVID-19 therapies once emergency use authorization in children at http://www.aap.org/nelsons Updated Nelson's app also available




Orthopaedic Knowledge Update® Pediatrics 6


Book Description

Orthopaedic Knowledge Update®: Pediatrics 6 reflects the most recent clinical practice guidelines and appropriate use criteria, as well as the substantial number of high-quality studies in pediatric orthopaedics. This comprehensive multispecialty resource explores the latest advances in pediatric trauma, sports-related injuries, and upper and lower extremity conditions, with brand-new chapters on developmental biology, metabolism, high-energy injury and polytrauma, elbow trauma, knee trauma, and disaster response. Recognized section editors and contributors bring fresh approaches and perspectives, with a focus on delivering a well-rounded update of this rapidly evolving subspecialty. This concentrated guide to new techniques, new approaches, and current controversies is ideal for anyone who treats pediatric musculoskeletal injuries.




Pocket Book of Hospital Care for Children


Book Description

The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.