Analysis of Quantal Response Data


Book Description

This book takes the standard methods as the starting point, and then describes a wide range of relatively new approaches and procedures designed to deal with more complicated data and experiments - including much recent research in the area. Throughout mention is given to the computing requirements - facilities available in large computing packages like BMDP, SAS and SPSS are also described.




Water & the Environment


Book Description

This compilation of papers provides useful insights on the differing approaches to water quality and the diversity of strategies in water quality management worldwide. Considering the current situation and looking to the future, the aim of this publication is to provide a sensible addition to the literature by concentrating on several important aspects of water and the environment.




An Introduction to the Interpretation of Quantal Responses in Biology


Book Description

The typical dose-response cure. The probit and similar transformations. The logit transformation. Calculations in probit analysis. Calculations in logit analysis. Quantal responses to mixtures of drugs. Dose-response curves from heterogeneous populations and detection of resistance in insects. Time and response. The general nature of quantal response.




Current Catalog


Book Description

First multi-year cumulation covers six years: 1965-70.




Introducing Quantitative Geography


Book Description

A unique introduction to contemporary quantitative geography, integrating material suitable for both introductory and more advanced courses. No previous knowledge is required and worked examples and computer analyses help student understanding.




Endocrine Disruption and Human Health


Book Description

Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations




Seeds, 3rd Edition


Book Description

The 3rd edition of Seeds: The Ecology of Regeneration in Plant Communities highlights the many advances in the field of seed ecology and its relationship to plant community dynamics that have taken place in recent years. The new edition also features chapters on seed development and morphology, seed chemical ecology, implications of climate change on regeneration by seed, and the functional role of seed banks in agricultural and natural ecosystems. The book is aimed at advanced level students and researchers in the fields of seed science, seed ecology and plant ecology.




Seeds


Book Description

Since the publication of our monograph on seed physiology and biochemistry (The Physiology and Biochemistry of Seeds in Relation to Germination, Sprin ger-Verlag, 1978, 1982), it has been suggested to us that a text covering the same subject area would be appropriate. This book is our response. Unlike the previous volumes, however, this text is not intended to be either a critical or a comprehensive account. Instead it is a more generalized consideration of the essential aspects of seed physiology and biochemistry as we see them. It also includes a substantial amount of new and different material. In a work of this sort it is inevitable that some simplifications must be made, but we hope, never theless, that we have presented the most reasonable conspectus of areas of con troversy and uncertainty. In this respect, literature citations have been kept to a minimum and do not interrupt the text; they are placed at the end of each chapter and are intended to be used as a source for further references. We hope that this book will be of value to students and teachers in uni versities, colleges, and other institutes of higher learning whose courses include plant biology. Although it is particularly appropriate for studies of seed biol ogy, it should also find broader applications in general plant physiology, agri culture, and horticulture.







Biopharmaceutical Applied Statistics Symposium


Book Description

This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments – particularly biopharmaceutical clinical trials. The papers were selected from invited presentations at the Biopharmaceutical Applied Statistics Symposium (BASS), which was founded by the first Editor in 1994 and has since become the premier international conference in biopharmaceutical statistics. The primary aims of the BASS are: 1) to raise funding to support graduate students in biostatistics programs, and 2) to provide an opportunity for professionals engaged in pharmaceutical drug research and development to share insights into solving the problems they encounter. The BASS book series is initially divided into three volumes addressing: 1) Design of Clinical Trials; 2) Biostatistical Analysis of Clinical Trials; and 3) Pharmaceutical Applications. This book is the third of the 3-volume book series. The topics covered include: Targeted Learning of Optimal Individualized Treatment Rules under Cost Constraints, Uses of Mixture Normal Distribution in Genomics and Otherwise, Personalized Medicine – Design Considerations, Adaptive Biomarker Subpopulation and Tumor Type Selection in Phase III Oncology Trials, High Dimensional Data in Genomics; Synergy or Additivity - The Importance of Defining the Primary Endpoint, Full Bayesian Adaptive Dose Finding Using Toxicity Probability Interval (TPI), Alpha-recycling for the Analyses of Primary and Secondary Endpoints of Clinical Trials, Expanded Interpretations of Results of Carcinogenicity Studies of Pharmaceuticals, Randomized Clinical Trials for Orphan Drug Development, Mediation Modeling in Randomized Trials with Non-normal Outcome Variables, Statistical Considerations in Using Images in Clinical Trials, Interesting Applications over 30 Years of Consulting, Uncovering Fraud, Misconduct and Other Data Quality Issues in Clinical Trials, Development and Evaluation of High Dimensional Prognostic Models, and Design and Analysis of Biosimilar Studies.