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Biosensor Based Advanced Cancer Diagnostics

Author : Raju Khan

Publisher : Academic Press

Page : 439 pages

File Size : 22,71 MB

Release : 2021-08-25

Category : Technology & Engineering

ISBN : 0128236515

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Book Description

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer



Biosensors and Molecular Technologies for Cancer Diagnostics

Author : Keith E. Herold

Publisher : Taylor & Francis

Page : 841 pages

File Size : 40,88 MB

Release : 2012-05-29

Category : Medical

ISBN : 1439841667

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Book Description

Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements



Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis

Author : Pranjal Chandra

Publisher : Springer

Page : 403 pages

File Size : 20,29 MB

Release : 2017-12-30

Category : Medical

ISBN : 981104726X

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Book Description

This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.



Biomarkers and Biosensors for Cervical Cancer Diagnosis

Author : John Bosco Balaguru Rayappan

Publisher : Springer Nature

Page : 115 pages

File Size : 34,34 MB

Release : 2021-07-28

Category : Medical

ISBN : 9811625867

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Book Description

This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.



Advanced Biosensors for Health Care Applications

Author : Dr. Inamuddin

Publisher : Elsevier

Page : 432 pages

File Size : 49,91 MB

Release : 2019-06-15

Category : Technology & Engineering

ISBN : 0128165227

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Book Description

Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. Describes advanced nanomaterials for biosensor applications Relates the properties of available nanomaterials to specific biomarkers applications Includes diagnosis and electrochemical studies based on biosensors Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies Describes novel strategies for developing a new class of assay systems to retrieve the desired health information



Nanobiosensors

Author : Aiguo Wu

Publisher : John Wiley & Sons

Page : 412 pages

File Size : 48,48 MB

Release : 2020-06-02

Category : Science

ISBN : 3527345108

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Book Description

Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.



Nanotechnology in Cancer Management

Author : Kamil Reza Khondakar

Publisher : Elsevier

Page : 252 pages

File Size : 46,72 MB

Release : 2021-05-18

Category : Technology & Engineering

ISBN : 0128181559

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Book Description

Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions. Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful. Includes smart sensing materials such as smart electro-active nanomaterials, sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical system, and device integration and interfacing for point-of-care applications Describes each component involved in the development of an efficient cancer diagnostics system Focuses on fundamental and applied concepts of the technologies, along with the related mechanisms proposed for diagnostics of cancer Enhances fundamental understandings of the concepts and development of nanotechnology based analytical tools and novel techniques for early stage cancer diagnostics and management



Advanced Biosensors for Virus Detection

Author : Raju Khan

Publisher : Academic Press

Page : 478 pages

File Size : 16,56 MB

Release : 2022-03-04

Category : Science

ISBN : 0323859895

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Book Description

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization. Deals with biosensors-based approaches that could be exploited to design and develop high throughput, rapid and cost-effective diagnostics technologies for the early detection of viral infections Illustrates the development of multiplexed, miniaturized analytical systems for point-of-care applications Provides information about fabrication protocols for various biosensor based diagnostic approaches that could be directly implemented to develop a novel biosensor Includes the past, present and future status of biosensors, along with information about biosensors currently under clinical trials



Biosensors and Cancer

Author : Victor R. Preedy

Publisher : CRC Press

Page : 426 pages

File Size : 47,6 MB

Release : 2012-07-27

Category : Medical

ISBN : 1578087341

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Book Description

Understanding the importance and application of biosensors is complicated by the diverse range of methods and applications. Furthermore, existing texts are somewhat technical in nature, making it difficult for the novice. This book disseminates information on biosensors in a readable way, suitable to a wide audience with varying levels of experience. Topics include optical imaging, surface plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.



Biosensors and Nanotechnology

Author : Zeynep Altintas

Publisher : John Wiley & Sons

Page : 420 pages

File Size : 27,85 MB

Release : 2017-11-16

Category : Technology & Engineering

ISBN : 1119065151

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Book Description

Provides a broad range of information from basic principles to advanced applications of biosensors and nanomaterials in health care diagnostics This book utilizes a multidisciplinary approach to provide a wide range of information on biosensors and the impact of nanotechnology on the development of biosensors for health care. It offers a solid background on biosensors, recognition receptors, biomarkers, and disease diagnostics. An overview of biosensor-based health care applications is addressed. Nanomaterial applications in biosensors and diagnostics are included, covering the application of nanoparticles, magnetic nanomaterials, quantum dots, carbon nanotubes, graphene, and molecularly imprinted nanostructures. The topic of organ-specific health care systems utilizing biosensors is also incorporated to provide deep insight into the very recent advances in disease diagnostics. Biosensors and Nanotechnology: Applications in Health Care Diagnostics is comprised of 15 chapters that are presented in four sections and written by 33 researchers who are actively working in Germany, the United Kingdom, Italy, Turkey, Denmark, Finland, Romania, Malaysia and Brazil. It covers biomarkers in healthcare; microfluidics in medical diagnostics; SPR-based biosensor techniques; piezoelectric-based biosensor technologies; MEMS-based cell counting methods; lab-on-chip platforms; optical applications for cancer cases; and more. Discusses the latest technology and advances in the field of biosensors and their applications for healthcare diagnostics Particular focus on biosensors for cancer Summarizes research of the last 30 years, relating it to state-of-the-art technologies Biosensors and Nanotechnology: Applications in Health Care Diagnostics is an excellent book for researchers, scientists, regulators, consultants, and engineers in the field, as well as for graduate students studying the subject.