Cholera and the Ecology of Vibrio cholerae


Book Description

Only in recent years has it been revealed that V. cholerae is a normal inhabitant of esturine and riverine waters. This means that even if the disease can be eliminated from human population by vaccines etc. the vibrio will continue to survive independently in the environment. It is likely that the environment is the source of epidemic strains. This is the first book to focus on the implication of these discoveries.




Cholera


Book Description

Research on cholera has contributed both to knowledge of the epidemic in particular, and to a broader understanding of the fundamental ways in which cells communicate with each other. This volume presents current knowledge in historical perspective to enable the practitioner to treat cholera in a more effective manner, and to provide a comprehensive review for the researcher.




Vibrios in the Environment


Book Description




Vibrio Cholerae and Cholera


Book Description

Presents the latest molecular studies of virulence, colonization, gene regulation, and the O1 antigen. Gives an in-depth and analytical approach to the epidemiology of cholera that includes outbreak investigations, case-control studies, and surveillance functions. Describes the molecular approach to epidemiologic problems and questions. Tracks the global spread of cholera by genetically defining individual strains. Addresses possible intervention and prevention strategies, including the latest vaccines, and their public health relevance.




Microbiology of Waterborne Diseases


Book Description

The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters




Vibrio ecology, pathogenesis and evolution


Book Description

Vibrios are Gram-negative bacilli that occur naturally in marine, estuarine, and freshwater systems. Some species include human and animal pathogens capable of causing gastroenteritis, wound infections, cholera, and fatal septicemia. Over the past decades, cutting edge research on Vibrio genomics has promoted a tremendous advance in our knowledge of these pathogens. Significant developments include the discovery of emerging epidemic clones, tracking the spread of new strain variants, and an intensified appreciation of the role of mobile genetic elements in antibiotic resistance spread as well as pathogenesis. Furthermore, improved understanding of the interaction of Vibrios with a variety of living organisms in the aquatic environment has documented the significant role of environmental reservoirs in their seasonal cycle favoring persistence of the pathogen during inter-epidemic periods and enhancing disease transmission. This Research Topic is dedicated to our current understanding in these areas and will bring together leading experts in the field to provide a deep overview of Vibrios ecology and evolution, and will suggest the pathway of future research in this field.




Molecular Medical Microbiology


Book Description

The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. - The first comprehensive and accessible reference on molecular medical microbiology - Full color presentation througout - In-depth discussion of individual pathogenic bacteria in a system-oriented approach - Includes a clinical overview for each major bacterial group - Presents the latest information on vaccine development, molecular technology, and diagnostic technology - More than 100 chapters covering all major groups of bacteria - Written by an international panel of authors who are experts in their respective disciplines




Africa in the Time of Cholera


Book Description

This book combines evidence from natural and social sciences to examine the impact on Africa of seven cholera pandemics since 1817, particularly the current impact of cholera on such major countries as Senegal, Angola, Mozambique, Congo, Zimbabwe and South Africa. Myron Echenberg highlights the irony that this once-terrible scourge, having receded from most of the globe, now kills thousands of Africans annually - Africa now accounts for more than 90 percent of the world's cases and deaths - and leaves many more with severe developmental impairment. Responsibility for the suffering caused is shared by Western lending and health institutions and by often venal and incompetent African leadership. If the threat of this old scourge is addressed with more urgency, great progress in the public health of Africans can be achieved.




Vibrio Cholerae


Book Description

The last decade has witnessed the unravelling of remarkable new insights into the biology of Vibrio cholerae. These include the discovery of the filamentous phage that encodes cholera toxin, the existence of two chromosomes in V. cholerae and the sequencing of the whole genome of the V. cholerae O1 strain N16961. These pioneering works led to an inevitable escalation in the amount of data generate. In this book we have endeavoured to distill the essence of this mighty deluge of information to produce a timely review of the genomics and molecular biology of this important human pathogen. Written by leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. choleraeincluding its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research.




Hunter's Tropical Medicine and Emerging Infectious Diseases E-Book


Book Description

New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules ... all significant, recent developments in the fast-changing field of tropical medicine. Hunter's Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You'll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control. - Includes important updates on malaria, leishmaniasis, tuberculosis and HIV, as well as coverage of Ebola, Zika virus, Chikungunya, and other emerging pathogens. - Provides new vaccine schedules and information on implementation. - Features five all-new chapters: Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration; Health System and Health Care Delivery; Zika; Medical Entomology; and Vector Control – as well as 250 new images throughout. - Presents the common characteristics and methods of transmission for each tropical disease, as well as the applicable diagnosis, treatment, control, and disease prevention techniques. - Contains skills-based chapters such as dentistry, neonatal pediatrics and ICMI, and surgery in the tropics, and service-based chapters such as transfusion in resource-poor settings, microbiology, and imaging. - Discusses maladies such as delusional parasitosis that are often seen in returning travelers, including those making international adoptions, transplant patients, medical tourists, and more. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.




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