Author : Reynold A. Panettieri, Jr., MD
Publisher : Integritas Communications
Page : 70 pages
File Size : 20,43 MB
Release : 2018-02-23
Category : Medical
ISBN : 0998419400
This eHealth SourceTM program examines best practices for assessing disease control in patients with severe asthma, the evidence for current and emerging biologic medications, and strategies to improve patient education and treatment adherence.
Author : Kian Fan Chung
Publisher : European Respiratory Society
Page : 360 pages
File Size : 20,33 MB
Release : 2019-06-01
Category : Medical
ISBN : 1849841047
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Author : Yong Chul Lee
Publisher : Springer
Page : 134 pages
File Size : 28,27 MB
Release : 2017-12-03
Category : Medical
ISBN : 9789811019975
This book presents state of the art knowledge on severe asthma with the aim of providing readers with a clear understanding of, first, the heterogeneity of the condition and of patients’ symptom profiles and responses to therapy and, second, the future implications of this heterogeneity for individualized patient care. After an opening section that offers an overview of severe asthma, including its clinical significance, the pathogenesis, available diagnostic approaches, and treatment options are described in detail. The sections on diagnosis and treatment cover the role of biomarkers, the use of radiologic diagnostic modalities, and both pharmacologic and non-pharmacologic therapies, including emerging options that will address hitherto unmet needs of patients. The outcomes of cutting-edge preclinical and clinical research are carefully documented and numerous useful tips provided on patient management. The inclusion of many informative schematic figures will assist readers in grasping the contents easily. The book will be of high value for medical students, researchers, general physicians, specialists, and paramedical staff.
Author : Jonathan Bernstein
Publisher : CRC Press
Page : 333 pages
File Size : 27,73 MB
Release : 2014-02-06
Category : Medical
ISBN : 1466585625
Enormous progress in asthma research has been made in the past 50 years, including a greater understanding of its complex pathogenesis and new and more effective therapies. Consequently, the scientific literature has grown vast and can be difficult to integrate. With contributions from a distinguished panel of world-renowned authors, Clinical Asthm
Author : Erick Forno
Publisher : Springer Nature
Page : 365 pages
File Size : 12,78 MB
Release : 2019-11-13
Category : Medical
ISBN : 3030274314
This book provides readers with a comprehensive review of severe asthma in children and adolescents, covering epidemiology, genetics, risk factors, co-morbidities, clinical presentation, diagnosis and treatment. Written by leaders in the field, chapter discussions draw on the mechanisms driving the disease, genetics, multidisciplinary approaches, immunomodulators, and other important aspects in the management of the disease. Severe Asthma in Children and Adolescents: Mechanisms and Management is designed to be a practical guide, opening with an introduction on the epidemiology of severe childhood asthma, as well as a discussion of special considerations of the disease unique to the preschool-aged patient. The distinctions between the diagnosis and management of asthma in young children of various ages, and specific approaches for the adolescent with severe asthma, including the transition into adult care are then addressed. Finally, the book closes with a discussion on the current state and future avenues for severe asthma research. Severe Asthma in Children and Adolescents is an indispensable reference for the healthcare professional, for basic and translational researchers, as well as for students, residents and fellows.
Author : Stanley J Szefler
Publisher : CRC Press
Page : 720 pages
File Size : 28,10 MB
Release : 2001-07-27
Category : Medical
ISBN : 9781135569280
Providing comprehensive coverage of the pathophysiology, pharmacology, and management of asthma from a multidisciplinary perspective, this thoroughly revised and updated reference reports the most recent breakthroughs in antiinflammatory therapies, herbal medications, airway remodeling, and disease prevention strategies. Addresses current dimensions of care, including genetics, occupational exposure, sleep disorders, and gastroesophageal reflux!
Author : Stanley J Szefler
Publisher : CRC Press
Page : 720 pages
File Size : 19,51 MB
Release : 2001-07-27
Category : Medical
ISBN : 9780824705527
Providing comprehensive coverage of the pathophysiology, pharmacology, and management of asthma from a multidisciplinary perspective, this thoroughly revised and updated reference reports the most recent breakthroughs in antiinflammatory therapies, herbal medications, airway remodeling, and disease prevention strategies. Addresses current dimensions of care, including genetics, occupational exposure, sleep disorders, and gastroesophageal reflux!
Author : Stanley J. Szefler
Publisher : Elsevier Health Sciences
Page : 237 pages
File Size : 31,51 MB
Release : 2017-09-22
Category : Medical
ISBN : 032349708X
Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. - Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. - Prepares you to meet your patients' needs regarding asthma exacerbation prevention and asthma prevention. - Consolidates today's available information and guidance in this timely area into one convenient resource.
Author : Sandhya Khurana
Publisher : Humana
Page : 334 pages
File Size : 46,90 MB
Release : 2019-09-25
Category : Medical
ISBN : 9783030208110
This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma ‘difficult to treat’. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate “difficult” from “severe refractory” asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes ‘state of the art’ reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.
Author : U. S. Department of Health and Human Services
Publisher : CreateSpace
Page : 74 pages
File Size : 20,33 MB
Release : 2012-06-26
Category : Medical
ISBN : 9781478138204
The National Institutes of Health Publication 08-5846 The Expert Panel Report 3 (EPR—3) Summary Report 2007: Guidelines for the Diagnosis and Management of Asthma was developed by an expert panel commissioned by the National Asthma Education and Prevention Program (NAEPP) Coordinating Committee (CC), coordinated by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Using the 1997 EPR—2 guidelines and the 2002 update on selected topics as the framework, the expert panel organized the literature review and updated recommendations for managing asthma long term and for managing exacerbations around four essential components of asthma care, namely: assessment and monitoring, patient education, control of factors contributing to asthma severity, and pharmacologic treatment. Subtopics were developed for each of these four broad categories. More than 22 million Americans have asthma, and it is one of the most common chronic diseases of childhood, affecting an estimated 6 million children. The burden of asthma affects the patients, their families, and society in terms of lost work and school, lessened quality of life, and avoidable emergency department (ED) visits, hospitalizations, and deaths. Improved scientific understanding of asthma has led to significant improvements in asthma care, and the National Asthma Education and Prevention Program (NAEPP) has been dedicated to translating these research findings into clinical practice through publication and dissemination of clinical practice guidelines. The first NAEPP guidelines were published in 1991, and updates were made in 1997, 2002, and now with the current report. Important gains have been made in reducing morbidity and mortality rates due to asthma; however, challenges remain. The NAEPP hopes that the “Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma—Full Report 2007” (EPR—3: Full Report 2007) will support the efforts of those who already incorporate best practices and will help enlist even greater numbers of primary care clinicians, asthma specialists, health care systems and providers, and communities to join together in making quality asthma care available to all people who have asthma. The goal, simply stated, is to help people with asthma control their asthma so that they can be active all day and sleep well at night.~
