Focus on Cognitive Disorder Research


Book Description

Cognitive disorders are defined as those in which a limitation of cognitive functioning is the main feature. They include: amnestic disorders, Huntington's disease, and mental retardation, dementia, delirium, aphasia, and cognitive disorders not otherwise specified. This book brings together leading researchers from throughout the world.




Cognitive Disorders


Book Description

This book contains selected peer-reviewed chapters that cover novel information on cognitive disorders and updated information on dementias written by international researchers. In this project, we discuss the effect of metabolic disorders on the development of cognitive disorders in patients with type 1 diabetes mellitus. In another chapter, the authors highlight the usability of an assistive software application developed for patients with dementia. On the other hand, an extensive review of novel information on different types of dementia is made. This chapter covers the novel aspect of dementia without ignoring its foundation. Therefore, apart from classic issues that cannot be missed in any textbook about cognitive disorders, we introduce updated information on the commonest dementias. The current situation of the prisoner population with dementia in a correctional setting is analyzed in another chapter, and specific recommendations to improve the health outcomes for prisoners are delivered. In more than one chapter, our authors wrote about a copious microtubule-associated protein (tau) as a biological fluid biomarker and tauopathies leading to cognitive disorder and cancer. Finally, the role of the hypothalamus in Alzheimer's disease is discussed. We look forward with confidence and pride to the remarkable role that this book will play for a new vision and mission.




Neuroimmunological Diseases


Book Description

This book offers a detailed review of the remarkable advances that have been made in research on the pathogenesis of a number of neuroimmunological diseases, as well as outlining novel treatments including the use of monoclonal antibodies. Written by renowned experts who have made major contributions in the field, such as identifying neuromyelitis optica as an immunopathological clinical condition, identifying the role of ganglioside and ganglioside-complex antibodies in Guillain-Barré syndrome, and developing a novel treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome, the book summarizes recent advances in basic and clinical research. Neuroimmunological Diseases is a useful resource for not only researchers but also neurologists who are engaged in the management of neuroimmunological diseases.










Leading-edge Cognitive Disorders Research


Book Description

This new book presents important recent research on cognitive disorders which are disturbances in the mental process related to thinking, reasoning, and judgement. They include delirium, dementia, and other cognitive disorders. Cognition includes the domains of attention, memory, language, gnosis, visuospatial function, praxis, and executive function, and is traditionally distinguished from the emotions or 'feelings'. Cognitive disorders may disturb one domain specifically, as in a selective impairment of memory (amnesia) or language (aphasia), or, more often, a combination of deficits, as in mental retardation and dementia.




Neurobiology of Disease


Book Description

The second edition of Neurobiology of Disease includes nearly 200 articles surveying all major disorders of the nervous system in both adults and children, focusing on relevant diagnosis and treatments from the perspective of cutting edge clinical and basic neurobiological research. Akin to an encyclopedia of every neurologic disorder, this comprehensive work is ideal for graduate and medical school students, residents, and candidates preparing for their board certification examinations. Each chapter is illustrated with detailed figures, supplemented with descriptive and diagnostic tables, and thoroughly referenced for further investigations. The book's editors, Michael V. Johnston, Harold P. Adams Jr., and Ali Fatemi bring their unique expertise in clinical and research neurology to the overall scope of this work. To further enhance the scope and quality of this new edition, the following Section Editors provided oversight of their respective sections: · Movement Disorders-Joel Perlmutter, Washington University · Dementias-David Knopman, Mayo Clinic · Motorneuron Diseases-Merit Cudkowicz, Massachusetts General Hospital · Paroxysmal Disorders-Solomon Moshe, Albert Einstein College of Medicine · Pediatric Neurology and Developmental Disorders-Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University · Neuroimmunological Diseases-Carlos Pardo-Villamizar, Johns Hopkins University · Cerebrovascular Diseases-Harold P. Adams Jr., University of Iowa · Peripheral and Autonomic Nervous System Disorders and Pain-Nicholas Maragakis, Johns Hopkins University · Neoplastic and Paraneoplastic Diseases-Lisa DeAngelis, Memorial Sloan-Kettering Cancer Center · Infectious Diseases of the Nervous System-Karen L. Roos, Indiana University · Sleep Disturbances-Mark Dyken, University of Iowa · Substance Abuse and Toxicology Disorders-Barry E. Kosofsky, Weill-Cornell University Medical Center · Neurologic Manifestations of Medical Disorders-John C. Probasco, Johns Hopkins University




Cognitive Disorders Research Trends


Book Description

Cognitive disorders are disturbances in the mental process related to thinking, reasoning, and judgement. They include delirium, dementia, and other cognitive disorders. Cognition includes the domains of attention, memory, language, gnosis, visuo-spatial function, praxis, and executive function, and is traditionally distinguished from the emotions or 'feelings'. Cognitive disorders may disturb one domain specifically, as in a selective impairment of memory (amnesia) or language (aphasia), or, more often, a combination of deficits, as in mental retardation and dementia.




The Neuroimmunological Basis of Behavior and Mental Disorders


Book Description

For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.