Cyclic Nucleotide Signaling


Book Description




Biochemistry of Smooth Muscle Contraction


Book Description

This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.







Jasper's Basic Mechanisms of the Epilepsies


Book Description

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.




Neural Plasticity and Memory


Book Description

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq




Investigation of Brain Function


Book Description

During the past fifteen or twenty years there have been remarkable advances in the methods of study of the functions of the brain in a wide range of species including man. As a result there has been a large increase in the factual knowledge of brain function but the interpretation and the application of these new facts has often tended to lag. The chapters in this book are the formal statements of those specialists of various disciplines who took part in a course of lectures and discussions of methods of the investigation of brain function in May 1980. Not only do they usually indicate the present state of knowledge and comprehension of the many functions of the brain of several species, but they also give valuable indications of where future studies might profitably be directed. G. Pampiglione A. W. Wilkinson v CONTENTS Steady State Radioisotopic Assessment of Brain Function . . . . . . . . 1 F. Fazio, C. Fieschi, and G. L. Lenzi Cerebral Blood Flow and Brain Function . 9 Bo Larsen Regional Cerebral Blood Flow and Regional Cerebral Oxygen Utilisation in Acute Cerebral Ischaemia . . . . . . 27 G. L. Lenzi, C. Fieschi, and F. Fazio The Electroencephalogram of Mental Abilities 35 Duilio Giannitrapani Sensory Processes and the Making of Decisions in Man . . . . . . . . . . . . . . . . . 59 R. Cooper Computed EEG Topography: Theory, Implementation and Application . . . . . . . . . . . . 79 Richard N. Harner Investigations of Apneic Syndrome during Sleep . . . . . . 103 D. Kurtz Automatic Analysis of Human Sleep EEGs . . . . . . . . . . 123 D. Samson-Dollfus Electrical Milestones in Mammalian Brain Development 139 G.




Molecular Aspects of Bioelectricity


Book Description

Molecular Aspects of Bioelectricity describes the self-organization in molecular and cellular networks. This book evaluates the chemical representation of ion flux gating in excitable biomembranes and addresses the theoretical implication of liganding reactions in axonal sodium channel gating. It also strongly demonstrates the ligand interactions of crustacean axonal membrane. The opening chapters deal with the biochemical studies of the structure, mechanism, and differentiation of the voltage-sensitive sodium channel; and biochemical cycle of impedance variation in axonal membranes. The succeeding chapters examine the effect of various compounds on the phosphorylation of nerve proteins and the molecular aspects of the actions of cyclic nucleotides at synapses. These topics are followed by discussions of the acetylcholine and choline acetyltransferase, as well as the polymorphism of cholinesterase in vertebrates. The closing chapters are devoted to the physical factors determining gated flux from and into sealed membrane fragments. The book can provide useful information to biologists, students, and researchers.







Molecular Approaches to Neurobiology


Book Description

Molecular Approaches to Neurobiology deals with molecular approaches to the analysis of the nervous system. This book surveys the current state of knowledge in a number of areas of molecular neurobiology that includes the subcellular level of chromatin structure, complexity of RNA synthesis, role of hormones in cell differentiation, and molecular correlates between neuropeptides and behavior. A comprehensive review of procedures for the isolation of specific brain cells and their experimental use is also provided at the end of this text. This publication is useful to those working in the field of neurochemistry and those engaged in morphological and physiological approaches to the analysis of the nervous system, as well as molecular biologists and biochemists working with non-neural tissues.




Research Awards Index


Book Description