Author : Kenneth Murphy
Publisher : Garland Science
Page : pages
File Size : 29,18 MB
Release : 2010-06-22
Category : Medical
ISBN : 9780815344575
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Anil Sukumaran
Publisher : BoD – Books on Demand
Page : 246 pages
File Size : 40,4 MB
Release : 2023-11-15
Category : Medical
ISBN : 1803562455
In the dynamic world of cellular biology, the intricate dance of life and death plays out through the lens of cytotoxicity. Delve deep into cellular responses’ mysteries, where threats and defenses wage a microscopic war, influencing the broader landscape of health and disease. This authoritative volume on cytotoxicity encapsulates the breadth and depth of current knowledge, illuminating pathways that have been meticulously charted and those yet to be discovered. Each chapter, penned by experts in the field, unveils the molecular intricacies, external triggers, and translational potential of understanding cellular damage. Key Highlights: •Comprehensive explorations of molecular mechanisms •Cutting-edge methodologies in cytotoxic research •Insight into the profound implications for drug development and disease therapeutics Whether you are a seasoned researcher, an aspiring scientist, or an avid learner, this book promises to challenge, enlighten, and inspire. As the boundary between known territories and uncharted frontiers blurs, Cytotoxicity - Understanding Cellular Damage and Response is your definitive guide to a world where cellular responses hold the keys to groundbreaking discoveries. This book is an indispensable resource for anyone eager to navigate the complexities of cell damage and defense. Join us on a journey into the cellular realm, where every page turns a new chapter in understanding, innovation, and hope.
Author : Erman Salih Istifli
Publisher : BoD – Books on Demand
Page : 120 pages
File Size : 12,98 MB
Release : 2019-10-02
Category : Medical
ISBN : 1789847540
Compensating for cytotoxicity in the multicellular organism by a certain level of cellular proliferation is the primary aim of homeostasis. In addition, the loss of cellular proliferation control (tumorigenesis) is at least as important as cytotoxicity, however, it is a contrasting trauma. With the disruption of the delicate balance between cytotoxicity and proliferation, confrontation with cancer can inevitably occur. This book presents important information pertaining to the molecular control of the mechanisms of cytotoxicity and cellular proliferation as they relate to cancer. It is designed for students and researchers studying cytotoxicity and its control.
Author :
Publisher :
Page : 0 pages
File Size : 25,41 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : Daniel Laskowitz
Publisher : CRC Press
Page : 388 pages
File Size : 41,44 MB
Release : 2016-04-21
Category : Medical
ISBN : 1498766579
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author : Sonia Soloneski
Publisher : BoD – Books on Demand
Page : 123 pages
File Size : 39,51 MB
Release : 2021-09-15
Category : Medical
ISBN : 1839687266
This edited book, Cytotoxicity - New Insights into Toxic Assessment, is intended to present some strategies, methods, interpretations and recent advances in order to facilitate scientific research on in vitro toxic responses, presenting both theoretical and practical aspects.
Author : Megan Chircop
Publisher : Frontiers Media SA
Page : 160 pages
File Size : 36,21 MB
Release : 2015-03-06
Category : Carcinogenesis
ISBN : 2889194965
In response to stress, cells can activate a myriad of signalling pathways to bring about a specific cellular outcome, including cell cycle arrest, DNA repair, senescence and apoptosis. This response is pivotal for tumour suppression as all of these outcomes result in restriction of the growth and/or elimination of damaged and pre-malignant cells. Thus, a large number of anti-cancer agents target specific components of stress response signalling pathways with the aim of causing tumour regression by stimulating cell death. However, the efficacy of these agents is often impaired due to mutations in genes that are involved in these stress-responsive signalling pathways and instead the oncogenic potential of a cell is increased leading to the initiation and/or progression of tumourigenesis. Moreover, these genetic defects can increase or contribute to resistance to chemotherapeutic agents and/or radiotherapy. Modulating the outcome of cellular stress responses towards cell death in tumour cells without affecting surrounding normal cells is thus one of the ultimate aims in the development of new cancer therapeutics. To achieve this aim, a detailed understanding of cellular stress response pathways and their aberrations in cancer is required. This Research topic aims to reflect the broadness and complexity of this important area of cancer research.
Author : Victor Kuete
Publisher : Elsevier
Page : 742 pages
File Size : 24,62 MB
Release : 2014-05-30
Category : Medical
ISBN : 0128004754
Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. - Offers a critical review of the methods used in toxicological survey of medicinal plants - Provides up-to-date toxicological data on African medicinal plants and families - Serves as a resource tool for students and scientists in the various areas of toxicology
Author : Xinguo Jiang
Publisher : Academic Press
Page : 368 pages
File Size : 26,67 MB
Release : 2016-10-03
Category : Medical
ISBN : 0128046201
Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. - Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology - Includes the most common nanoparticles, their applications, and mechanisms - Provides one of the first books to focus on nanomedicine and neurotoxicity
Author : Edward J. Moticka
Publisher : Newnes
Page : 396 pages
File Size : 17,5 MB
Release : 2015-11-25
Category : Medical
ISBN : 0123983754
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. - Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles - Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology - Presents concepts such as the division of lymphocytes into functionally different populations in their historical context - Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
