Author : Vernon Bryson
Publisher :
Page : 664 pages
File Size : 24,50 MB
Release : 1965
Category : Biochemistry
ISBN :
Details new perspectives of structural and functional features of proteins and nucleic acids in biochemistry.
Author : Joram Piatigorsky
Publisher : Harvard University Press
Page : 434 pages
File Size : 49,98 MB
Release : 2007-02-28
Category : Science
ISBN : 9780674023413
In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
Author : Eugene V. Koonin
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 47,72 MB
Release : 2013-06-29
Category : Science
ISBN : 1475737831
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.
Author :
Publisher :
Page : 0 pages
File Size : 38,67 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : Tobias Sikosek
Publisher : Humana
Page : 0 pages
File Size : 22,79 MB
Release : 2018-10-09
Category : Science
ISBN : 9781493987351
This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Computational Methods in Protein Evolution is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.
Author : Sean B. Carroll
Publisher : W. W. Norton & Company
Page : 388 pages
File Size : 23,35 MB
Release : 2005
Category : Science
ISBN : 9780393060164
As described in this fascinating book, Evo Devo is evolutionary development biology, the third revolution in the science, which shows how the endless forms of animals--butterflies and zebras, trilobites and dinosaurs, apes and humans--were made and evolved.
Author : National Academy of Sciences
Publisher :
Page : 388 pages
File Size : 45,15 MB
Release : 2007
Category : Science
ISBN :
The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Author : Austin L. Hughes
Publisher : Oxford University Press, USA
Page : 286 pages
File Size : 33,46 MB
Release : 1999
Category : Science
ISBN : 9780195116267
It will be an invaluable tool for anyone interested or working in molecular or evolutionary biology, and for those studying the implications of our rapidly increasing knowledge of the genomes of organisms."--BOOK JACKET.
Author : Paul G. Higgs
Publisher : John Wiley & Sons
Page : 532 pages
File Size : 37,68 MB
Release : 2013-04-30
Category : Science
ISBN : 1118697065
In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.
Author : Simon Easteal
Publisher : Springer
Page : 190 pages
File Size : 41,78 MB
Release : 1995
Category : Nature
ISBN :
This book is about the rate of molecular evolution in mammals. Various methods of comparative analysis have been applied to different kinds of molecular data in attempts to resolve the issue. The choice of molecular data, and more importantly, the different assumptions made in the analysis have resulted in contrasting conclusions being drawn. These assumptions are critically evaluated and draw the conclusion that for "silent" DNA the molecular clock hypothesis cannot be rejected. For amino acids the clock hypothesis is rejected and this appears to reflect the action of natural selection. The implications of the DNA clock in relation to the pattern of mammalian evolution and the process of mutation are discussed.
