Fluoroquinolone-Associated Disability (FQAD) - Pathogenesis, Diagnostics, Therapy and Diagnostic Criteria


Book Description

In this book, Stefan Pieper supports doctors and therapists in easily diagnosing FQAD and in better and more adequately dealing with FQAD patients. Fluoroquinolones, as one of the most common and effective groups of antibiotics, are known to have a distinct spectrum of side effects. These adverse effects are rare in percentage terms, but frequent in absolute numbers due to the enormous quantities of prescriptions. Because they are usually quite severe and wide-ranging, they tend to run like a syndrome and have been classified by the FDA as a separate condition, the FQAD, because of their frequency, severity and risk of disability. This book presents for the first time a comprehensive description and classification of the clinical picture and a proposal for a clinical diagnostic tool based on diagnostic criteria.




Fluoroquinolone-Associated Disability (FQAD) - Pathogenesis, Diagnostics, Therapy and Diagnostic Criteria


Book Description

In this book, Stefan Pieper supports doctors and therapists in easily diagnosing FQAD and in better and more adequately dealing with FQAD patients. Fluoroquinolones, as one of the most common and effective groups of antibiotics, are known to have a distinct spectrum of side effects. These adverse effects are rare in percentage terms, but frequent in absolute numbers due to the enormous quantities of prescriptions. Because they are usually quite severe and wide-ranging, they tend to run like a syndrome and have been classified by the FDA as a separate condition, the FQAD, because of their frequency, severity and risk of disability. This book presents for the first time a comprehensive description and classification of the clinical picture and a proposal for a clinical diagnostic tool based on diagnostic criteria.




Cough: Pathophysiology, Diagnosis and Treatment


Book Description

This book provides an updated and comprehensive overview of cough, while opening new perspectives for their treatment and management. It enables readers to not only discover new physiologic features and mechanisms but also to gain an in-depth understanding of the diagnostic workup of cough, still one of the most frequent and challenging symptoms in daily medical practice. The book also provides insights into cough’s features and pathogenesis, as well as into pharmacologic and non-pharmacologic treatments. The most frequent causes of chronic cough (asthma, postnasal drip, gastroesophageal reflux and chronic hypersensitivity syndrome) and different types of pediatric cough are also explored. Coughing is a common symptom, occurring in many clinical settings, and as such the book appeals a broad readership, including pulmonologists specialized in cough, general practitioners, internists, pediatricians and otorhinolaryngologists.




Clinical Applications of Mifepristone (RU486) and Other Antiprogestins


Book Description

Mifepristone (RU486), the first clinically available antiprogestin, has generated great interest since its discovery in the early 1980s. Today, it is recognized that mifepristone, along with other antiprogestins, has a potentially significant therapeutic role in human health and disease, with likely applicability to a variety of pregnancy-related conditions (e.g., management of labor) and to contraception, endometriosis, and cancer, among others. But because mifepristone has been studied and used most widely as a means of nonsurgical abortion, political issues have thus far limited research on the drug and prevented its introduction into the U.S. market. This book provides an unbiased evaluation of current knowledge about both the fundamental nature of antiprogestins as well as their possible use in treating numerous diseases and conditions, and it contains recommendations for future research.




Ciprofloxacin


Book Description




Androgen Deficiency and Testosterone Replacement


Book Description

Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of the book will serve as a source of basic information about testosterone replacement and as a source of reasoned analysis of the controversies surrounding testosterone replacement in the aging male. Physicians and physician extenders will be able to apply evidence management principles to the evaluation and treatment of men with testosterone deficiency; supported by the most recent practice guidelines available. The authors represent a select group of physicians with expertise in androgen deficiency and replacement. Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies will be of great value to all physicians and physician extenders who deliver health care to men of all ages.




Leishmania and Leishmaniasis


Book Description

​Leishmania-related illnesses remain among the world’s deadliest neglected tropical diseases, affecting approximately 12 million people in 88 countries. The mortality rate is substantial, contributing to nearly two million disability-adjusted life years. As more is understood about this parasite and its effects, work toward prevention, control, and treatment continues apace. Leishmania and Leishmaniasis will address the parasite and its attendant disease, which manifests in three syndromes: Visceral (VL), Cutaneous (CL) and Mucocutaneous Leishmaniasis (ML). The morphology and life cycles of the various species will be among the topics addressed in Part One. Part Two will focus on immunology, including host-immune response to Leishmania infection, cross-immunity between the different species and adoptive transfer of immunity. Parts Three and Four will address how Leishmania invade and survive, the clinical features of the disease, and its diagnosis. Drugs, vaccines and treatment will be thoroughly explored, including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a thorough examination of a parasite, the illnesses it causes and the misery it continues to visit upon large segments of the population.​




What You Must Know About the Hidden Dangers of Antibiotics


Book Description

While the news about taking too many antibiotics is now common knowledge, there is another underlying danger that the public is not aware of. As beneficial as this class of drugs are, there is a widely prescribed family of antibiotics that is highly destructive. Called fluoroquinolones, they are better known under the names Cipro and Levaquin (as well as four others). What You Must Know About the Hidden Dangers of Antibiotics, has two main goals. The first is to expose the truly destructive capability of these drugs to cause serious, sometimes long term and permanent injuries. The capacity of these drugs for such damage has been attested to by the government’s own watchdog agency, the FDA. Hundreds of patients, many of whom are quoted in this book, have confirmed their long-lasting injuries to the book’s author, Dr. Jay Cohen, while many hundreds more have been ignored or dismissed by their own physicians. As this book will show, being brushed off and dismissed as simple side effects essentially allows these manufactures to hide these problems from public view. The second goal of this book is to provide other safer and effective remedies, solutions, and considerations that may help end the suffering experienced by patients suffering from these dangerous side effects--that can affect many human systems including the musculoskeletal, nervous, psychiatric, gastrointestinal, and others. To do this we explain how these dangerous antibiotics work, and particularly how they injure. By understanding the underlying problems, the alternatives offered in this book can help people potentially reduce their pain reduction, clear up persistent antibiotic-based health issues, and just as important, give them hope. Because so many doctors do not carefully read the FDA’s dire warnings about the risks these specific antibiotics pose, there is little likely patients will be know why they are having such serious reactions. With What You Must Know About the Hidden Dangers of Antibiotics, they may have the answer they are looking for.




Diagnosis of the Temporomandibular Joint


Book Description

This book provides a comprehensive overview of the diagnostic imaging techniques of the temporomandibular joint with emphasis on the pathophysiology of disk displacement and disk dysfunction. The reader is given a detailed understanding of the anatomy, normal and abnormal function and guidance as to the best imaging technique for diagnosis and staging. The complimentary role of arthroscopy is presented in detail, and new techniques in the diagnosis of rheumatic diseases of the TMJ are presented as well. The imaging modalities utilized as tools for diagnosis include plain films, arthrography, computerized tomography (CT), radionuclide imaging and magnetic resonance (MR) imaging. Heavily illustrated with a wealth of pathological specimens and imaging studies.




How We Can Halt the Cipro and Levaquin Catastrophe


Book Description

This book is about the powerful, sometimes lifesaving, yet sometimes highly destructive antibiotics known as fluoroquinolones. Best known of these drugs are Cipro (ciprofloxacin) and Levaquin (levofloxacin), as well as four others. This book, How We Can Halt the Cipro and Levaquin Catastrophe: the Worst Medication Disaster in U.S. History, has two main goals. The first goal is to alert patients and doctors of the truly destructive capability of these drugs to cause serious, sometimes long term, sometimes permanent injuries. The capacity of these drugs for such damage has been attested by the U.S. Food and Drug Administration and others many times and is by now incontrovertible. Hundreds of patients, many of whom are quoted in this book, have confirmed their long-lasting injuries to me, while many hundreds more have been ignored or dismissed by their doctors. This must stop. Ignoring these problems has only made the problem worse. My second goal in writing How We Can Halt the Cipro and Levaquin Catastrophe: the Worst Medication Disaster in U.S. History is to stimulate the interest of government, the drug industry, medical institutions and all others for any and all ideas regarding remedies, solutions, and any other ideas that may help end the suffering experienced by patients with the Fluoroquinolone Toxicity Syndrome that can affect many human systems including the musculoskeletal, nervous, psychiatric, gastrointestinal, and others. As you will see, I have offered some ideas for therapies that may provide benefit to some of the injured. I think it is imperative that we follow a trail that may lead us to an understanding of how these drugs work and particularly how they injure, and most of all how we might help people heal, obtain pain reduction and hope. Thousands of lives, young and old, depend on the efforts that we make.