Frontiers in Clinical Drug Research - Hematology: Volume 5


Book Description

Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The fifth volume of this series features 7 reviews with a focus on thalassemia treatment and preeclampsia among other topics. - Recent advances in the diagnosis and management of pulmonary embolism - An evidence-based approach to treatment with iron chelators in transfusion- dependent thalassemia patients: present trends and future scenario - Current and future treatments of iron overload in thalassemia patients - Preeclampsia: biological and clinical aspects - Haematological modulations by fixed dose combination (FDC) of tramadol hydrochloride/paracetamol (THP) - Possible use of eculizumab in critically ill patients infected with covid-19 role of complement c5, neutrophils, and nets in the induction DIC, sepsis, and MOF hematological markers - Emerging diagnostic and therapeutic targets in preeclampsia




Frontiers in Clinical Drug Research - Hematology: Volume 4


Book Description

Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The fourth volume of this series features 5 reviews: -TRP Channels: Potential Therapeutic Targets in Blood Disorders -Hypercoagulable States: Clinical Symptoms, Laboratory Markers and Management -Advanced Applications of Gene Therapy in the Treatment of Hematologic Disorders -Ferroptosis - Importance and Potential Effects in Hematological Malignancies -Clinical Application of Liquid Biopsy in Solid Tumor HCC: Prognostic, Diagnostic and Therapy Monitoring Tool.




Frontiers in Clinical Drug Research: Hematology


Book Description

Frontiers in Clinical Drug Research - Hematology is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the eBo




Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 5


Book Description

Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology researchers. The fifth volume of the book features reviews on biochemical inhibitors (second-generation protein kinase Inhibitors, histone deacetylase inhibitors, immune checkpoint inhibitors, EGFR Tyrosine Kinase inhibitors, non-coding RNAs), apoptosis, and physical exercise therapy for cancer patients undergoing chemotherapy. The treatment strategies in this volume cover cancers such as acute myeloid leukemia, gastrointestinal cancer, breast cancer and lung cancer.




Frontiers in Clinical Drug Research - Hematology


Book Description

Frontiers in Clinical Drug Research - Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research - Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The second volume of this series features 5 chapters that cover a variety of topics including: -Chronic myeloid leukemia -Bispecific and multivalent antibodies -Natural Killer cells therapy for bone marrow transplantation -Nanoparticles in health and disease -Monoclonal antibody therapy for lymphoma




Index of Conference Proceedings


Book Description




The Metric Tide


Book Description

‘Represents the culmination of an 18-month-long project that aims to be the definitive review of this important topic. Accompanied by a scholarly literature review, some new analysis, and a wealth of evidence and insight... the report is a tour de force; a once-in-a-generation opportunity to take stock.’ – Dr Steven Hill, Head of Policy, HEFCE, LSE Impact of Social Sciences Blog ‘A must-read if you are interested in having a deeper understanding of research culture, management issues and the range of information we have on this field. It should be disseminated and discussed within institutions, disciplines and other sites of research collaboration.’ – Dr Meera Sabaratnam, Lecturer in International Relations at the School of Oriental and African Studies, University of London, LSE Impact of Social Sciences Blog Metrics evoke a mixed reaction from the research community. A commitment to using data and evidence to inform decisions makes many of us sympathetic, even enthusiastic, about the prospect of granular, real-time analysis of our own activities. Yet we only have to look around us at the blunt use of metrics to be reminded of the pitfalls. Metrics hold real power: they are constitutive of values, identities and livelihoods. How to exercise that power to positive ends is the focus of this book. Using extensive evidence-gathering, analysis and consultation, the authors take a thorough look at potential uses and limitations of research metrics and indicators. They explore the use of metrics across different disciplines, assess their potential contribution to the development of research excellence and impact and consider the changing ways in which universities are using quantitative indicators in their management systems. Finally, they consider the negative or unintended effects of metrics on various aspects of research culture. Including an updated introduction from James Wilsdon, the book proposes a framework for responsible metrics and makes a series of targeted recommendations to show how responsible metrics can be applied in research management, by funders, and in the next cycle of the Research Excellence Framework. The metric tide is certainly rising. Unlike King Canute, we have the agency and opportunity – and in this book, a serious body of evidence – to influence how it washes through higher education and research.




Frontiers in Clinical Drug Research - Hematology


Book Description

"Frontiers in Clinical Drug Research - Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research - Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The third volume of this series features 6 reviews: -Advances in the understanding and treatment of immune thrombocytopenia -Recent developments in chronic myeloid leukemia biology and treatment -Role of immunomodulatory drugs in the treatment of lymphoid and myeloid malignancies -Pediatric hematological malignancies - clinical manifestation, treatment and follow-up -Novel therapies and immunotherapeutic approaches to treat childhood leukemia -Erythrocyte turnover and erythropoietic patterns in two different experimental mouse models of anemia"







The Ageless Generation


Book Description

An assessment of recent advances in biomedical science evaluates their potential role in shaping the future of health care, retirement, and the global economy.




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