Hydrazines and Cancer


Book Description

This comprehensive publication on biological actions of hydrazines includes all the available published material and chronological descriptions of the literature. The uniformly applied principle of evaluations separates each hydrazine chemical and divides according to species. This monograph presents data on carcinogenic activity of hydrazines in animals.




How Tobacco Smoke Causes Disease


Book Description

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.




Acute Exposure Guideline Levels for Selected Airborne Chemicals


Book Description

This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports.




Carcinogens and Anticarcinogens in the Human Diet


Book Description

Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.




Emergency and Continuous Exposure Guidance Levels for Selected Submarine Contaminants


Book Description

U.S. Navy personnel who work on submarines are in an enclosed and isolated environment for days or weeks at a time when at sea. Unlike a typical work environment, they are potentially exposed to air contaminants 24 hours a day. To protect workers from potential adverse health effects due to those conditions, the U.S. Navy has established exposure guidance levels for a number of contaminants. The Navy asked a subcommittee of the National Research Council (NRC) to review, and develop when necessary, exposure guidance levels for 10 contaminants. Overall, the subcommittee found the values proposed by the Navy to be suitable for protecting human health. For a few chemicals, the committee proposed levels that were lower than those proposed by the Navy. In conducting its evaluation, the subcommittee found that there is little exposure data available on the submarine environment and echoed a previous recommendation from an earlier NRC report to conduct monitoring that would provide a complete analysis of submarine air and data on exposure of personnel to contaminants.




Chemical Carcinogenesis


Book Description

During October 18-30, 1981, the second course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the International Union Against Cancer, the Italian League Against Cancer, the Italian Ministry of Public Education, the Italian Ministry of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and two pharmaceutical Companies (Zambeletti and Farmitalia). The subject of the course was "Chemical Carcino genesis" with participants selected world-wide from 18 different countries. It is now eminently clear that.the bulk of human cancers are related to one of several types of environmental exposure. Of the environmental hazards, chemicals are among the best characterized carcinogens. However, how chemicals induce cancer is still poorly understood. Because of the magnitude of the problem and the ob vious need for a much more critical scientific analysis of the process by which cancer is induced (carcinogenesis), it was highly desirable to expose a greater number of scientists with varying background to some of the latest thinking in chemical carcino genesis. The course had this as its major objective and the re sulting book does reflect it.




Diet Nutrition And Cancer


Book Description

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.




Alternatives in Cancer Therapy


Book Description

Alternatives in Cancer Therapy offers help for all patients coping with cancer. The therapies discussed in this book are primarily non-toxic, have few, if any, side effects, and tend to strengthen the immune system. They can be used as supplemental regimens that help maximize the effectiveness of traditional therapies such as surgery, radiation, and chemotherapy. Patients have a right to know all of their treatment options, and Dr. Ross Pelton presents dozens of choices, including: * Shark Cartilage * Gerson Therapy * Mistletoe * Isoprinosine * Laetrile * Selenium * Beta-Carotene * Hydrogen Peroxide * Vitamins C and E * The Hoxsey Treatment Non-traditional therapies can enhance the quality of life, and improve overall health while treating the disease. Alternatives in Cancer Therapy provides information on the research, efficacy, potential side effects, and availability of each treatment.




Cancers of the Mouth and Throat


Book Description

William Lydiatt, M.D. and Perry Johnson, M.D., have worked with hundreds of mouth and throat cancer patients. They understand the emotional turmoil patients and their families go through after a cancer diagnosis, and they know how being informed can relieve some of that stress. Topics covered in this book include how early detection leaads to high cure rates; symptoms that could mean cancer; the emotional side of the cancer; how doctors make a diagnosis; staging the cancer and why it so important; surgery, radiation, and chemotherapy—how they kill cancer; reconstructive surgery; and experimental treatment through clinical trials.