Molecular Biology of the Cell
Author :
Publisher :
Page : 0 pages
File Size : 34,69 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Opportunities in Biotechnology for Future Army Applications
Author : National Research Council
Publisher : National Academies Press
Page : 118 pages
File Size : 36,87 MB
Release : 2001-07-11
Category : Science
ISBN : 0309075556
Book Description
This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
IMMUNE BIOTECHNOLOGY
Author : Gunasekaran Thirumurugan
Publisher : Gunasekaran Thirumurugan
Page : 346 pages
File Size : 10,49 MB
Release : 2020-04-13
Category : Medical
ISBN :
Book Description
This book covers the whole immunology and immune technology of pharmaceutical aspects; it begins with the main players of immunology and covers all components of immunology such as complement, antigens, immunoglobulin’s, antigen-antibody reactions and selected tests, cells involved In immune responses and antigen recognition. Chapter seven covers the major histocompatibility complex (MHC) and t-cell receptors - role in immune responses. Chapter eight deals with the response to antigen: Processing and presentation MHC restriction and role of the thymus. Moreover, cell-mediated immunity, cytokines and immunoregulation, immunization, MHC: genetics and role in transplantation is discussed in this section. Tolerance and autoimmunity, hypersensitivity reactions, tumor immunology and immunodeficiency is discussed in the subsequent chapters. Finally, Hybridoma technology for production of monoclonal antibodies, vaccine technology and immunological techniques is discussed in the last three chapters.This book is written as there need of text book for the students of medical and paramedical discipline such as Pharmacy, Medicine etc., and biotechnology, biomedical, Biochemical, microbiology, biochemistry from both engineering and biology backgrounds. The main features of this book are that the coverage of various Indian Universities curriculum of the aforesaid subjects and each contains illustrations to understand the subject matter.
Janeway's Immunobiology
Author : Kenneth Murphy
Publisher : Garland Science
Page : pages
File Size : 43,15 MB
Release : 2010-06-22
Category : Medical
ISBN : 9780815344575
Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Blood Groups and Red Cell Antigens
Author : Laura Dean
Publisher :
Page : pages
File Size : 29,24 MB
Release : 2005
Category : Blood group antigens
ISBN :
Book Description
Cancer Immunology and Immunotherapy
Author : Mansoor M. Amiji
Publisher : Academic Press
Page : 550 pages
File Size : 23,25 MB
Release : 2021-08-18
Category : Medical
ISBN : 012823637X
Book Description
Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Comprehensive treaty covering all aspects of immuno-oncology (IO) - Novel strategies for delivery of IO therapeutics and vaccines - Forecasting on the future of nanotechnology and drug delivery for IO
Immune Rebalancing
Author : Diana Boraschi
Publisher : Academic Press
Page : 300 pages
File Size : 37,44 MB
Release : 2016-01-25
Category : Medical
ISBN : 0128033363
Book Description
Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc. - Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes - Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections - Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches - Provides information on the new strategies for drug development in this field - Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations
Antibodies and Their Role in Therapeutics
Author : Roohi Bansal
Publisher : Roohi Bansal
Page : 390 pages
File Size : 50,27 MB
Release : 2021-12-04
Category :
ISBN : 9789355781604
Book Description
Beginning with the structure, types, functions, and gene organization of antibodies, the book aims to shine a detailed light on the monoclonal antibodies (often referred to as mAbs) that have revolutionized the fields of therapeutics and diagnostics. The book describes the different ways of generating chimeric, humanized, and fully human monoclonal antibodies, emphasizing phage display, hybridoma, and rDNA technology. In addition, the book focuses on the various recombinant antibody formats in detail: Drug conjugates: Antibody-drug conjugates (ADCs), Immunotoxins (Recombinant, Humanized and Fully Human) and Antibody-antibiotic conjugate (AAC) Bispecific antibodies: scFv based (BiTE, DARTs and TandAbs) and Full-length IgG based Abzymes and Antibody-directed enzyme prodrug therapy (ADEPT) Fc-fusion proteins Single-domain antibodies (VHH and IgNAR sdAb) The book discusses the various therapeutic applications of monoclonal antibodies, along with the immunogenicity issues. The book also covers the modes of administration and side effects of monoclonal antibodies, along with the challenges and issues faced while developing a monoclonal antibody into a therapeutic agent. Modifications introduced by the researchers to decrease the immunogenicity issues and increase the efficacy of therapeutic mAbs are also described. The book is an invaluable resource for researchers and students in biology and medicine, biotechnology, immunology, genetics, molecular biology, and anyone interested in antibody engineering.
Biotechnology for Beginners
Author : Reinhard Renneberg
Publisher : Academic Press
Page : 476 pages
File Size : 46,20 MB
Release : 2023-01-16
Category : Science
ISBN : 0323855709
Book Description
Biotechnology for Beginners, Third Edition presents the latest developments in the evolving field of biotechnology which has grown to such an extent over the past few years that increasing numbers of professional's work in areas that are directly impacted by the science. This book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy and animal science. This book will also appeals to lay readers who do not have a scientific background but are interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Loroch discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome. - Covers the whole of biotechnology - Presents an extremely accessible style, including lavish and humorous illustrations throughout - Includes new chapters on CRISPR cas-9, COVID-19, the biotechnology of cancer, and more
B Cell Receptor Signaling
Author : Tomohiro Kurosaki
Publisher : Springer
Page : 233 pages
File Size : 25,12 MB
Release : 2015-12-26
Category : Medical
ISBN : 3319261339
Book Description
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
