In Search of Memory: The Emergence of a New Science of Mind


Book Description

“A stunning book.”—Oliver Sacks Memory binds our mental life together. We are who we are in large part because of what we learn and remember. But how does the brain create memories? Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind—a combination of cognitive psychology, neuroscience, and molecular biology—with his own personal quest to understand memory. A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings readers from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the twentieth century: the search for the biological basis of memory.




The Disordered Mind


Book Description

A Nobel Prize–winning neuroscientist’s probing investigation of what brain disorders can tell us about human nature Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts. In his seminal new book, The Disordered Mind, Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. But sometimes those connections are disrupted. The brain processes that give rise to our mind can become disordered, resulting in diseases such as autism, depression, schizophrenia, Parkinson’s, addiction, and post-traumatic stress disorder. While these disruptions bring great suffering, they can also reveal the mysteries of how the brain produces our most fundamental experiences and capabilities—the very nature of what it means to be human. Studies of autism illuminate the neurological foundations of our social instincts; research into depression offers important insights on emotions and the integrity of the self; and paradigm-shifting work on addiction has led to a new understanding of the relationship between pleasure and willpower. By studying disruptions to typical brain functioning and exploring their potential treatments, we will deepen our understanding of thought, feeling, behavior, memory, and creativity. Only then can we grapple with the big question of how billions of neurons generate consciousness itself.




Reductionism in Art and Brain Science


Book Description

Are art and science separated by an unbridgeable divide? Can they find common ground? In this new book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science can inform the way we experience a work of art and seek to understand its meaning. Kandel illustrates how reductionism—the distillation of larger scientific or aesthetic concepts into smaller, more tractable components—has been used by scientists and artists alike to pursue their respective truths. He draws on his Nobel Prize-winning work revealing the neurobiological underpinnings of learning and memory in sea slugs to shed light on the complex workings of the mental processes of higher animals. In Reductionism in Art and Brain Science, Kandel shows how this radically reductionist approach, applied to the most complex puzzle of our time—the brain—has been employed by modern artists who distill their subjective world into color, form, and light. Kandel demonstrates through bottom-up sensory and top-down cognitive functions how science can explore the complexities of human perception and help us to perceive, appreciate, and understand great works of art. At the heart of the book is an elegant elucidation of the contribution of reductionism to the evolution of modern art and its role in a monumental shift in artistic perspective. Reductionism steered the transition from figurative art to the first explorations of abstract art reflected in the works of Turner, Monet, Kandinsky, Schoenberg, and Mondrian. Kandel explains how, in the postwar era, Pollock, de Kooning, Rothko, Louis, Turrell, and Flavin used a reductionist approach to arrive at their abstract expressionism and how Katz, Warhol, Close, and Sandback built upon the advances of the New York School to reimagine figurative and minimal art. Featuring captivating drawings of the brain alongside full-color reproductions of modern art masterpieces, this book draws out the common concerns of science and art and how they illuminate each other.




The Age of Insight


Book Description

A brilliant book by Nobel Prize winner Eric R. Kandel, The Age of Insight takes us to Vienna 1900, where leaders in science, medicine, and art began a revolution that changed forever how we think about the human mind—our conscious and unconscious thoughts and emotions—and how mind and brain relate to art. At the turn of the century, Vienna was the cultural capital of Europe. Artists and scientists met in glittering salons, where they freely exchanged ideas that led to revolutionary breakthroughs in psychology, brain science, literature, and art. Kandel takes us into the world of Vienna to trace, in rich and rewarding detail, the ideas and advances made then, and their enduring influence today. The Vienna School of Medicine led the way with its realization that truth lies hidden beneath the surface. That principle infused Viennese culture and strongly influenced the other pioneers of Vienna 1900. Sigmund Freud shocked the world with his insights into how our everyday unconscious aggressive and erotic desires are repressed and disguised in symbols, dreams, and behavior. Arthur Schnitzler revealed women’s unconscious sexuality in his novels through his innovative use of the interior monologue. Gustav Klimt, Oscar Kokoschka, and Egon Schiele created startlingly evocative and honest portraits that expressed unconscious lust, desire, anxiety, and the fear of death. Kandel tells the story of how these pioneers—Freud, Schnitzler, Klimt, Kokoschka, and Schiele—inspired by the Vienna School of Medicine, in turn influenced the founders of the Vienna School of Art History to ask pivotal questions such as What does the viewer bring to a work of art? How does the beholder respond to it? These questions prompted new and ongoing discoveries in psychology and brain biology, leading to revelations about how we see and perceive, how we think and feel, and how we respond to and create works of art. Kandel, one of the leading scientific thinkers of our time, places these five innovators in the context of today’s cutting-edge science and gives us a new understanding of the modernist art of Klimt, Kokoschka, and Schiele, as well as the school of thought of Freud and Schnitzler. Reinvigorating the intellectual enquiry that began in Vienna 1900, The Age of Insight is a wonderfully written, superbly researched, and beautifully illustrated book that also provides a foundation for future work in neuroscience and the humanities. It is an extraordinary book from an international leader in neuroscience and intellectual history.




Searching For Memory


Book Description

Memory. There may be nothing more important to human beings than our ability to enshrine experience and recall it. While philosophers and poets have elevated memory to an almost mystical level, psychologists have struggled to demystify it. Now, according to Daniel Schacter, one of the most distinguished memory researchers, the mysteries of memory are finally yielding to dramatic, even revolutionary, scientific breakthroughs. Schacter explains how and why it may change our understanding of everything from false memory to Alzheimer's disease, from recovered memory to amnesia with fascinating firsthand accounts of patients with striking -- and sometimes bizarre -- amnesias resulting from brain injury or psychological trauma.




There Is Life After the Nobel Prize


Book Description

One day in 1996, the neuroscientist Eric R. Kandel took a call from his program officer at the National Institute of Mental Health, who informed him that he had been awarded a key grant. Also, the officer said, he and his colleagues thought Kandel would win the Nobel Prize. “I hope not soon,” Kandel’s wife, Denise, said when she heard this. Sociologists had found that Nobel Prize winners often did not contribute much more to science, she explained. In this book, Kandel recounts his remarkable career since receiving the Nobel in 2000—or his experience of proving to his wife that he was not yet “completely dead intellectually.” He takes readers through his lab’s scientific advances, including research into how long-term memory is stored in the brain, the nature of age-related memory loss, and the neuroscience of drug addiction and schizophrenia. Kandel relates how the Nobel Prize gave him the opportunity to reach a far larger audience, which in turn allowed him to discover and pursue new directions. He describes his efforts to promote public understanding of science and to put brain science and art into conversation with each other. Kandel also discusses his return to Austria, which he had fled as a child, and observes Austria’s coming to terms with the Nazi period. Showcasing Kandel’s accomplishments, erudition, and wit, There Is Life After the Nobel Prize is a candid account of the working life of an acclaimed scientist.




Science of Memory


Book Description

Scientists currently study memory from many different perspectives: neurobiological, ethological, animal conditioning, cognitive, behavioral neuroscience, social, and cultural. The aim of this book is to help initiate a new science of memory by bringing these perspectives together to create a unified understanding of the topic. The book began with a conference where leading practitioners from all these major approaches met to analyze and discuss 16 concepts that are crucial to our understanding of memory. Each of these 16 concepts is addressed in a section of the book, and in the 66 succinct chapters that fill these sections, a leading researcher addresses the section's concept by clearly stating his or her position on it, elucidating how it is used, and discussing how it should be used in future research. For some concepts, there is general agreement among practitioners from different fields and levels of analysis, but for others there is general disagreement and much controversy. A final chapter in each section, also written by a leading researcher, integrates the various viewpoints offered on the section's concept, then draws conclusions about the concept. This groundbreaking volume will be an indispensable reference for all the students and researchers who will build upon the foundation it provides for the new science of memory.




Memory


Book Description

Combining insights from both cognitive neuroscience and molecular biology, two of the world's leading experts address memory from molecules and cells to brain systems and cognition. What is memory and where in the brain is it stored? How is memory storage accomplished? This book touches on these questions and many more, showing how the recent convergence of psychology and biology has resulted in an exciting new synthesis of knowledge about learning and remembering. Memory: From Mind to Molecules is an ideal primer for courses on learning and memory or for general readers who are interested in discovering what is currently known about one of the basic aspects of human existence.




Spineless


Book Description

"A book full of wonders" —Helen Macdonald, author of H Is for Hawk "Witty, insightful. . . .The story of jellyfish. . . is a significant part of the environmental story. Berwald's engaging account of these delicate, often ignored creatures shows how much they matter to our oceans' future." —New York Times Book Review Jellyfish have been swimming in our oceans for well over half a billion years, longer than any other animal that lives on the planet. They make a venom so toxic it can kill a human in three minutes. Their sting—microscopic spears that pierce with five million times the acceleration of gravity—is the fastest known motion in the animal kingdom. Made of roughly 95 percent water, some jellies are barely perceptible virtuosos of disguise, while others glow with a luminescence that has revolutionized biotechnology. Yet until recently, jellyfish were largely ignored by science, and they remain among the most poorly understood of ocean dwellers. More than a decade ago, Juli Berwald left a career in ocean science to raise a family in landlocked Austin, Texas, but jellyfish drew her back to the sea. Recent, massive blooms of billions of jellyfish have clogged power plants, decimated fisheries, and caused millions of dollars of damage. Driven by questions about how overfishing, coastal development, and climate change were contributing to a jellyfish population explosion, Juli embarked on a scientific odyssey. She traveled the globe to meet the biologists who devote their careers to jellies, hitched rides on Japanese fishing boats to see giant jellyfish in the wild, raised jellyfish in her dining room, and throughout it all marveled at the complexity of these alluring and ominous biological wonders. Gracefully blending personal memoir with crystal-clear distillations of science, Spineless is the story of how Juli learned to navigate and ultimately embrace her ambition, her curiosity, and her passion for the natural world. She discovers that jellyfish science is more than just a quest for answers. It’s a call to realize our collective responsibility for the planet we share.




The Seven Sins of Memory


Book Description

A New York Times Notable Book: A psychologist’s “gripping and thought-provoking” look at how and why our brains sometimes fail us (Steven Pinker, author of How the Mind Works). In this intriguing study, Harvard psychologist Daniel L. Schacter explores the memory miscues that occur in everyday life, placing them into seven categories: absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence. Illustrating these concepts with vivid examples—case studies, literary excerpts, experimental evidence, and accounts of highly visible news events such as the O. J. Simpson verdict, Bill Clinton’s grand jury testimony, and the search for the Oklahoma City bomber—he also delves into striking new scientific research, giving us a glimpse of the fascinating neurology of memory and offering “insight into common malfunctions of the mind” (USA Today). “Though memory failure can amount to little more than a mild annoyance, the consequences of misattribution in eyewitness testimony can be devastating, as can the consequences of suggestibility among pre-school children and among adults with ‘false memory syndrome’ . . . Drawing upon recent neuroimaging research that allows a glimpse of the brain as it learns and remembers, Schacter guides his readers on a fascinating journey of the human mind.” —Library Journal “Clear, entertaining and provocative . . . Encourages a new appreciation of the complexity and fragility of memory.” —The Seattle Times “Should be required reading for police, lawyers, psychologists, and anyone else who wants to understand how memory can go terribly wrong.” —The Atlanta Journal-Constitution “A fascinating journey through paths of memory, its open avenues and blind alleys . . . Lucid, engaging, and enjoyable.” —Jerome Groopman, MD “Compelling in its science and its probing examination of everyday life, The Seven Sins of Memory is also a delightful book, lively and clear.” —Chicago Tribune Winner of the William James Book Award




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