Insights in Rheumatology: 2021


Book Description







Textbook of Pediatric Rheumatology


Book Description

Clinical reference designed to aid in the care of children with rheumatic diseases. Offers guidelines for interpreting the signs, symptoms and laboratory abnormalities that accompany these disorders. Includes numerous halftone illustrations and tables, radiographs, and other figures.




New Insights into Autoinflammatory Diseases: From Bench to Bedside


Book Description

Systemic autoinflammatory diseases (SAIDs) are a growing group of rare disorders caused by dysregulation of the innate immune system leading to episodes of organ-specific and systemic inflammation. Autoinflammation as a distinct disease category was first reported in 1999 as a group of monogenic disorders with resultant activation of the inflammasome and cytokine excess, presenting as periodic fever and inflammation in serous membranes. Since this original description, the focus has shifted considerably to the inclusion of complex multifactorial conditions, and more than 30 associated genes have been identified. Disease severity varies from mild to life threatening. Advances in the understanding of the pathogenetic role of interleukin-1, have opened new promising horizons in the treatment of these patients, and significantly altered disease outcome.







Pediatric Rheumatology Comes of Age: Part II, An Issue of Rheumatic Disease Clinics of North America, E-Book


Book Description

In this issue of Rheumatic Disease Clinics, Guest Editors Laura E. Schanberg? MD and Yukiko Kimura? MD brings his considerable expertise to the topic of pediatric rheumatology. Top experts in the field cover key topics such as CARRA, Mental health, Social media and JIA, CV disease in PRD, and more. - Provides in-depth, clinical reviews on pediatric rheumatology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 20 relevant, practice-oriented topics, such as Pharmacosurveillance of biologics in pediatric rheumatic disease (or JIA); cSLE in developing countries: impact of access to care, ethnic differences?; Biomarkers and Outcome Measures in cSLE; Role of environment on PRD; and more.




Multisystem Inflammatory Syndrome in Children


Book Description

Since April 2020, pediatric patients in Europe and the USA were reported presenting Kawasaki Disease-like shock syndrome. These patients showed pictures of variable severity up to multiorgan involvement and hyper inflammation, sometimes requiring intensive care. The CDC later defined this condition as Multisystem Inflammatory Syndrome in Children (MIS-C). The following diagnostic criteria were established: age <21 years; fever >24 hours; blood chemistry tests compatible with an inflammatory state; involvement of at least 2 organs or systems; severe clinical conditions requiring hospitalization; exclusion of other possible diagnoses, recent exposure (>4 weeks) to SARS-CoV-2 or positive nasopharyngeal swab or previous infection ascertained on serological examination. The immunopathogenesis of MIS-C is unclear but overlapping features with Kawasaki disease suggestive of vasculitis and a likely autoimmune etiology has been described.




Biochemical and Molecular Basis of Pediatric Disease


Book Description

Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. - Provides a fully-updated resource with more color illustrations - Focuses on the biochemical and molecular basis of disease as well as the analytical techniques - Defines important differences in the pathophysiology of diseases, comparing childhood with adult




Pediatric Rheumatology Comes of Age: Part I, An Issue of Rheumatic Disease Clinics of North America, E-Book


Book Description

This issue of Rheumatic Disease Clinics, guest edited by Drs. Laura Schanberg and Yukiko Kimura, will focus on Pediatric Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman. Part II, also edited by Drs. Kimura and Schanberg, will publish subsequently and cover additional topics relevant for pediatric rheumatologists. Topics discussed in this issue include but are not limited to: TMJ, CNO (CRMO), Update JIA treatment, Pharmacology of biologics in kids, Juvenile Spondylitis, Juvenile fibro update, JDM update, Pediatric Sjogrens, Localized scleroderma, Systemic Sclerosis, Uveitis, COVID-19 in pediatrics, Recent advances in pediatric vasculitis, and Autoinflammatory diseases. - Provides in-depth, clinical reviews on the latest updates in Pediatric Rheumatology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.




Recent Books