The Evaluation of Forensic DNA Evidence


Book Description

In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.







Investigation of the Hydraulics of Horizontal Drains in Plumbing Systems


Book Description

Results are reported from an investigation of the hydraulics of flow in experimental apparatus simulating nominally horizontal simple and branching drains of plumbing systems. The data are correlated with limited findings in an earlier, unpublished NBS study the results of which have been utilized in current plumbing codes. The need for further research is pointed out, particularly in relation to hydraulic performance of drain systems as affected by steep slopes, drain storage volume, energy losses at stack bases, attenuation of water depths and discharge rates in long drains, and large drain diameters.







Guide to Evidence-Based Physical Therapist Practice


Book Description

Guide to Evidence-Based Physical Therapist Practice, Fifth Edition teaches the knowledge and skills to evaluate medical evidence and apply it to the practice of physical therapy. This valuable reference explains the fundamentals of medical research and how to determine which studies are useful in practice. As the leading evidence-based practice text for physical therapy, this is a comprehensive resource no physical therapist or student should be without. This practical guide empowers readers to learn how to evaluate research designs, appraise evidence, and apply research in clinical practice. Its reader-friendly style facilitates learning and presents the knowledge essential for physical therapist students to develop a strong foundation in research methods and methodologies related to evidence-based medicine.










Process Control System Fault Diagnosis


Book Description

Process Control System Fault Diagnosis: A Bayesian Approach Ruben T. Gonzalez, University of Alberta, Canada Fei Qi, Suncor Energy Inc., Canada Biao Huang, University of Alberta, Canada Data-driven Inferential Solutions for Control System Fault Diagnosis A typical modern process system consists of hundreds or even thousands of control loops, which are overwhelming for plant personnel to monitor. The main objectives of this book are to establish a new framework for control system fault diagnosis, to synthesize observations of different monitors with a prior knowledge, and to pinpoint possible abnormal sources on the basis of Bayesian theory. Process Control System Fault Diagnosis: A Bayesian Approach consolidates results developed by the authors, along with the fundamentals, and presents them in a systematic way. The book provides a comprehensive coverage of various Bayesian methods for control system fault diagnosis, along with a detailed tutorial. The book is useful for graduate students and researchers as a monograph and as a reference for state-of-the-art techniques in control system performance monitoring and fault diagnosis. Since several self-contained practical examples are included in the book, it also provides a place for practicing engineers to look for solutions to their daily monitoring and diagnosis problems. Key features: • A comprehensive coverage of Bayesian Inference for control system fault diagnosis. • Theory and applications are self-contained. • Provides detailed algorithms and sample Matlab codes. • Theory is illustrated through benchmark simulation examples, pilot-scale experiments and industrial application. Process Control System Fault Diagnosis: A Bayesian Approach is a comprehensive guide for graduate students, practicing engineers, and researchers who are interests in applying theory to practice.




Studying a Study and Testing a Test


Book Description

Now in its Fifth Edition, this best-selling text presents a step-by-step approach to critical and efficient reading of the medical literature. Health care professionals will learn how to evaluate clinical studies, identify flaws in study design, interpret statistics, and apply evidence from clinical research in practice. This edition's new section, Guide to the Guidelines, reflects the growing use and importance of clinical guidelines. The outcomes research chapter includes concepts of safety and effects of interactions on outcomes. This edition also presents statistics more graphically. Unique learning aids include question checklists, scenarios illustrating study design, and flaw-catching exercises, plus a StudyingaStudy.com Website providing interactive materials.