The Discovery of Insulin


Book Description

The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.




Insulin Action


Book Description

In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.




Polycystic Ovary Syndrome


Book Description

This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.




Mechanisms of Insulin Action


Book Description

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.




Islands and Insulin


Book Description

What if doctors declared you would never again do the one thing you felt you were born to do? After surviving with diabetes for years, Erin Spineto was quickly losing her sanity. Buried beneath blood tests, injections, and medical devices, she had to do something drastic. A sailor at heart, could she give up her passion to play it safe with diabetes? If she went, her blood sugars could plummet while alone in the middle of the ocean. Seasickness could raise blood sugars and slam her into a diabetic coma, leaving her incapable of handling the boat. In “the most entertaining diabetes book I've read to date…," Erin navigates her twenty-two-foot sailboat down the Florida Keys as she fights winds, currents, and swells that threaten to capsize her. (Amy Tenderich, Founder and Editor of Diabetes Mine) In a time when doctors advised people with diabetes “avoid any extreme exertion,” will Erin push the boundaries of what is possible or find out the hard way she should have listened to the warnings? Fans of The World’s Worst Diabetes Mom and The Insulin Express will love this thrilling and uplifting story about one girl’s defiance of those who would stand in her way. Don't miss out on the action of this unforgettable journey. Click the BUY NOW button and sail away with Erin on her journey to accepting diabetes as she navigates those tumultuous early years of adulthood and learns how valuable real friendships are in the battle against a chronic disease.




Cheating Destiny


Book Description

Examines the disease that is becoming America's fastest-growing epidemic, revealing the author's own bout with Type 1 diabetes, the science behind the disease, and the social and economic impact of diabetes in the United States.




Hypoglycemia in Diabetes


Book Description

Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.




Unveiling Diabetes - Historical Milestones in Diabetology


Book Description

A history of diabetology told by renowned contributors, many have themselves already become a part of diabetes history. A must-have for every diabetologist! Diabetologists, diabetes educators, and many interested readers will appreciate this book. What is more, countless celebrations are planned for the 100th anniversary of the discovery of insulin: this book provides numerous illustrations, accounts of personal experiences, and critical remarks on the history of diabetology – in addition to the history of insulin. It spans an arc from antiquity to the work of Claude Bernard, Paul Langerhans, Josef von Mering, Apollinaire Bouchardat, Oskar Minkowski, E.P. Joslin, and F.M. Allen. The history of insulin is presented from the perspective of diabetologists from Scotland, Spain, Germany, and Poland. The history of oral antidiabetics is told by Harald Lebovitz, and the chapter about glitazones by Edwin Gale reads like a spy novel! Pierre Lefèbvre describes the work of the diabetologist Jean Pirart and the history of glucagon. Sir George Alberti has provided a chapter about the therapy of ketoacidosis, to which he himself made groundbreaking contributions. Nephropathy is presented by Hans-Henrik Parving, and Eva Kohner, Ronald Klein and Barbara E.K. Klein have contributed a chapter on retinopathy. Other contemporary topics such diabetes in pregnancy, diabetes technology, psychosocial aspects of diabetes, and the history of the EASD and ADA are also included in this book.




Balancing Diabetes


Book Description

When a person receives a diagnosis of diabetes, he or she starts a process of adjusting and making sense of the new normal living with a chronic disease. A large part of that adjustment is figuring out how to balance diabetes with all the intricacies of a life outside of diabetes care. In Balancing Diabetes, diabetes online community blogger Kerri Sparling compiles strategies used by people with diabetes and their caregivers to bring that elusive balance into their lives. Whether adult or child, type 1 or type 2, spouse or caregiver, male or female, people in the diabetes world will find themselves in this book and be inspired by the commonality of that continuing search for balance.




Mastering Diabetes


Book Description

The instant New York Times bestseller. A groundbreaking method to master all types of diabetes by reversing insulin resistance. Current medical wisdom advises that anyone suffering from diabetes or prediabetes should eat a low-carbohydrate, high-fat diet. But in this revolutionary book, Cyrus Khambatta, PhD, and Robby Barbaro, MPH, rely on a century of research to show that advice is misguided. While it may improve short-term blood glucose control, such a diet also increases the long-term risk for chronic diseases like cancer, high blood pressure, high cholesterol, chronic kidney disease, and fatty liver disease. The revolutionary solution is to eat a low-fat plant-based whole-food diet, the most powerful way to reverse insulin resistance in all types of diabetes: type 1, type 1.5, type 2, prediabetes, and gestational diabetes. As the creators of the extraordinary and effective Mastering Diabetes Method, Khambatta and Barbaro lay out a step-by-step plan proven to reverse insulin resistance-the root cause of blood glucose variability- while improving overall health and maximizing life expectancy. Armed with more than 800 scientific references and drawing on more than 36 years of personal experience living with type 1 diabetes themselves, the authors show how to eat large quantities of carbohydrate-rich whole foods like bananas, potatoes, and quinoa while decreasing blood glucose, oral medication, and insulin requirements. They also provide life-changing advice on intermittent fasting and daily exercise and offer tips on eating in tricky situations, such as restaurant meals and family dinners. Perhaps best of all: On the Mastering Diabetes Method, you will never go hungry. With more than 30 delicious, filling, and nutrient-dense recipes and backed by cutting-edge nutritional science, Mastering Diabetes will help you maximize your insulin sensitivity, attain your ideal body weight, improve your digestive health, gain energy, live an active life, and feel the best you've felt in years.