Author : Karen Lambert
Publisher : Frontiers Media SA
Page : 123 pages
File Size : 45,66 MB
Release : 2022-07-01
Category : Science
ISBN : 2889764745
Topic Editor Dr. Philippe Connes has received a grant from HARTIS Pharma (Switzerland-France). All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Author : Alessandra Castegna
Publisher : Frontiers Media SA
Page : 231 pages
File Size : 33,26 MB
Release : 2020-12-18
Category : Medical
ISBN : 2889662624
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Charles Tipton
Publisher : Human Kinetics
Page : 608 pages
File Size : 46,12 MB
Release : 2014-04-01
Category : Science
ISBN : 1492584398
History of Exercise Physiology brings together leading authorities in the profession to present this first-of-its-kind resource that is certain to become an essential reference for exercise physiology researchers and practitioners. The contributing authors were selected based on their significant contributions to the field, including many examples in which they were part of seminal research. The result of this vast undertaking is the most comprehensive resource on exercise physiology research ever compiled. Exercise physiology research is ongoing, and its knowledge base is stronger than ever. But today’s scholars owe much of their success to their predecessors. The contributors to this book believe it is essential for exercise physiologists to understand the past when approaching the future, and they have compiled this reference to aid in that process. The text includes the following features: • A broad scope of the primary ideas and work done in exercise physiology from antiquity to the present • A review of early contributions to exercise physiology made by Scandinavian scientists, the Harvard Fatigue Laboratory, German laboratories, and the Copenhagen Muscle Research Centre • The incorporation of molecular biology into exercise biology and physiology research that paved the way for exercise physiology • An explanation of the relationship between genomics, genetics, and exercise biology • An integrative view of the autonomic nervous system in exercise • An examination of central and peripheral influences on the cardiovascular system • An in-depth investigation and analysis of how exercise influences the body’s primary systems •A table in most chapters highlighting the significant research milestones Well illustrated with figures and photos, History of Exercise Physiology helps readers understand the research findings and meet the most prominent professionals in the field. From studying great thinkers of antiquity and cutting-edge work done by pioneers at research institutions, to exploring the inner workings of all the body’s systems, researchers will gain a precise understanding of what happens when human bodies move—and who influenced and furthered that understanding.
Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 30,79 MB
Release : 2016-08-18
Category : Medical
ISBN : 1615047212
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author : Johannes Hirrlinger
Publisher : Humana Press
Page : 0 pages
File Size : 20,49 MB
Release : 2014-09-16
Category : Medical
ISBN : 9781493910588
Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultures which allow assessing of the properties and functions of a single brain cell type with many different types of analysis, however, at the expense of neglecting the interaction between cell types in the brain. On the other end, analysis in animals and humans in vivo is discussed, maintaining the full complexity of the tissue and the organism but making high demands on the methods of analysis. Written for the popular Neuromethods series, chapters include the kind of detailed description and key implementation advice that aims to support reproducible results in the lab. Meticulous and authoritative, Brain Energy Metabolism provides an ideal guide for researchers interested in brain energy metabolism with the hope of stimulating more research in this exciting and very important field.
Author : Thorsten Cramer
Publisher : Springer
Page : 272 pages
File Size : 11,27 MB
Release : 2016-08-24
Category : Medical
ISBN : 3319421182
This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
Author : Yuansheng Gao
Publisher : Springer Nature
Page : 422 pages
File Size : 38,81 MB
Release : 2022-12-08
Category : Medical
ISBN : 9811971226
This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on newly identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The second edition intends to update the contents of the first edition with the latest achievements in the regulation of vascular activities from biochemical, structural, genetic, physiological, and pharmacological aspects. In addition, two new chapters related to microRNA and extracellular vesicles have been added to reflect their newly discovered important roles in vascular activities. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting to physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.
Author : Denise Smith
Publisher : Lippincott Williams & Wilkins
Page : 2060 pages
File Size : 12,4 MB
Release : 2022-07-12
Category : Medical
ISBN : 1975179560
With this new 6th Edition, Exercise Physiology for Health, Fitness, and Performance continues to provide an authoritative resource for mastering exercise physiology. This engaging, accessible and approachable resource integrates theoretical and research-based basic exercise physiology with real-world application to prepare students for exciting positions in exercise science, fitness, physical education, athletic training, rehabilitation, coaching, and/or allied health professions. Updated throughout, the text uses sound pedagogical principles to explain scientific research that is the foundation of exercise physiology and incorporates multiple features to help students apply their knowledge to improve human health, fitness, and performance. Content in this edition is organized by independent units (Metabolic, Cardiovascular-Respiratory, Neuromuscular-Skeletal, and Neuroendocrine-Immune), offering maximum teaching flexibility for faculty and ensuring a consistent, efficient, and effective learning experience for students.
Author : Michael J. Joyner
Publisher : Perspectives Cshl
Page : 408 pages
File Size : 33,59 MB
Release : 2017
Category : Medical
ISBN : 9781621821656
Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes enhance physical performance, improve mental health, and delay the onset of aging and disease. Understanding the molecular basis of these changes is therefore important for optimizing athletic ability and for developing drugs that elicit therapeutic effects. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines the biological basis of exercise from the molecular to the systemic levels. Contributors discuss how transcriptional regulation, cytokine and hormonal signaling, glucose metabolism, epigenetic modifications, microRNA profiles, and mitochondrial and ribosomal functions are altered in response to exercise training, leading to improved skeletal muscle, hippocampal, and cardiovascular function. Cross talk among the pathways underlying tissue-specific and systemic responses to exercise is also considered. The authors also discuss how the understanding of such molecular mechanisms may lead to the development of drugs that mitigate aging and disease. This volume will therefore serve as a vital reference for all involved in the fields of sports science and medicine, as well as anyone seeking to understand the molecular mechanisms by which exercise promotes whole-body health.
Author : Thomas Fahey
Publisher : Independently Published
Page : 415 pages
File Size : 24,74 MB
Release : 2019-09-03
Category :
ISBN : 9781687591715
Second of a two volume set.
