Biosynthesis of Branched Chain Amino Acids


Book Description

This book reflects the growing interest in the pathways of the biosynthesis of branched-chain amino acids. With contributions from various subdisciplines, it represents an extensive state-of-the-art report. Numerous aspects of the biosynthesis of branched-chain amino acids are covered, such as control of gene expression, the interaction among metabolic pathways under physiological conditions and unusual circumstances, and the stereochemical and mechanistic aspects of enzymes involved. It also considers possible applications to biotechnological problems and the development of novel herbicides. Special Feature: An extensive general bibliography to help the reader find further important information on the subject.




Metal Transporters


Book Description

This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise







Basics of Toxicology


Book Description

Toxicology--the scientific study of environmental factors that are harmful to living organisms--was established more than 400 years ago by the Swiss physician Paracelsus. Yet, despite its long lineage, this fascinating discipline continues to evolve sophisticated new tools and techniques for identifying toxins and the means by which they impair health. This book provides environmental technology students with an enjoyable and effective way to acquire the solid working knowledge of toxicology basics they'll need to make informed decisions as professionals. Features that make Basics of Toxicology an ideal introduction to the subject for two-year and four-year environmental technology students, include: * Acclaimed, user-friendly, modular format found in all the books in the Preserving the Legacy series * Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue * Rapid-learning chapter structure, featuring clear, concise objectives, concept statements, and summaries, as well as practice questions * Helpful sidebars that highlight critical concepts * More than 150 high-quality line-drawings, photographs, diagrams, charts, and tables * Numerous easy-to-perform, skill-building activities * A glossary of more than 800 essential terms * Extensive bibliography of recommended readings in all key subject areas * Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue Its comprehensive scope along with its quick-reference design also makes Basics of Toxicology a handy working reference for practicing environmental technicians.







Hydrolytic Enzymes


Book Description

This newest volume in the impressive New Comprehensive Biochemistry series presents up-to-date discussions of six types of hydrolytic enzyme that are well characterized structurally: aspartic-, cysteins-, and serine-proteinases, carboxypeptidase A, pancreatic ribonuclease A, and the phosphomonoesterases. The emphasis is on molecular mechanisms deduced by crystallographic, kinetic, spectroscopic and molecular genetic studies. The chapters on the various types of proteinases are complemented by others on proteinase inhibitors and intracellular proteolysis. This book will prove valuable to researchers in general biochemistry, particularly those with interest in enzyme mechanism and protein chemistry, and to Honours and Postgraduate students.




Biomolecular Electronics


Book Description

Biomolecular Electronics – the electrical control of biological phenomena – is a scientific challenge that, once fully realized, will find a wide range of applications from electronics and computing to medicine and therapeutic techniques.This new arena of biomolecular electronics is approached using familiar concepts from many areas such as electrochemistry, device electronics and some mechanisms of gene expression level control. Practical techniques are explored by which electrical and electronic means can be used to control biological reactions and processes. Also, the current and future applications for this new and expanding field are discussed.This book is aimed at scientists and engineers involved in both research and commercial applications across fields including bioelectronics, bionanotechnology, electrochemistry and nanomedicine – providing a state-of-the-art survey of what's going on at the boundary between biology and electronic technology at the micro- and nano- scales, along with a suggestive insight into future possible developments. - Demystifies the science and applications of electrically-driven biological reactions - Explains how the techniques of bioelectronics and electrochemistry can be deployed as biological control technologies - Provides applications information for diverse areas from bio-electrochemistry to electrical control of gene expression levels




Redox Biochemistry


Book Description

This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.