Metalloenzymes in Denitrification


Book Description

The reduction of nitrate to nitrogen by metalloenzymes is a vital step in the nitrogen cycle. The importance of this pathway has inspired efforts to understand in greater depth the mechanisms involved. This book presents and discusses the latest information on multiple aspects of denitrification. Written by recognized specialists in the field, this book describes the bioinorganic aspects and the key enzymes involved in denitrification, including their structure, function and mechanisms. Active site modelling, novel methodologies for monitoring denitrification in vivo and biotechnological methods for water treatment are discussed. The book also focusses on the environmental implications of denitrification, such nitrate accumulation and the release of nitrous oxide into the atmosphere from excessive fertiliser use. An important topic in many biological, environmental and agricultural contexts, this book will aid teaching and help bioinorganic chemists and biotechnologists gain an up-to-date picture of the science behind the denitrification process.




Metalloenzymes in Denitrification


Book Description

The reduction of nitrate to nitrogen by metalloenzymes is a vital step in the nitrogen cycle. The importance of this pathway has inspired efforts to understand in greater depth the mechanisms involved. This book presents and discusses the latest information on multiple aspects of denitrification. Written by recognized specialists in the field, this book describes the bioinorganic aspects and the key enzymes involved in denitrification, including their structure, function and mechanisms. Active site modelling, novel methodologies for monitoring denitrification in vivo and biotechnological methods for water treatment are discussed. The book also focusses on the environmental implications of denitrification, such nitrate accumulation and the release of nitrous oxide into the atmosphere from excessive fertiliser use. An important topic in many biological, environmental and agricultural contexts, this book will aid teaching and help bioinorganic chemists and biotechnologists gain an up-to-date picture of the science behind the denitrification process.







Biological Wastewater Treatment: Principles, Modeling and Design


Book Description

The first edition of this book was published in 2008 and it went on to become IWA Publishing’s bestseller. Clearly there was a need for it because over the twenty years prior to 2008, the knowledge and understanding of wastewater treatment had advanced extensively and moved away from empirically-based approaches to a fundamental first-principles approach based on chemistry, microbiology, physical and bioprocess engineering, mathematics and modelling. However the quantity, complexity and diversity of these new developments was overwhelming for young water professionals, particularly in developing countries without readily available access to advanced-level tertiary education courses in wastewater treatment. For a whole new generation of young scientists and engineers entering the wastewater treatment profession, this book assembled and integrated the postgraduate course material of a dozen or so professors from research groups around the world who have made significant contributions to the advances in wastewater treatment. This material had matured to the degree that it had been codified into mathematical models for simulation with computers. The first edition of the book offered, that upon completion of an in-depth study of its contents, the modern approach of modelling and simulation in wastewater treatment plant design and operation could be embraced with deeper insight, advanced knowledge and greater confidence, be it activated sludge, biological nitrogen and phosphorus removal, secondary settling tanks, or biofilm systems. However, the advances and developments in wastewater treatment have accelerated over the past 12 years since publication of the first edition. While all the chapters of the first edition have been updated to accommodate these advances and developments, some, such as granular sludge, membrane bioreactors, sulphur conversion-based bioprocesses and biofilm reactors which were new in 2008, have matured into new industry approaches and are also now included in this second edition. The target readership of this second edition remains the young water professionals, who will still be active in the field of protecting our precious water resources long after the aging professors who are leading some of these advances have retired. The authors, all still active in the field, are aware that cleaning dirty water has become more complex but that it is even more urgent now than 12 years ago, and offer this second edition to help the young water professionals engage with the scientific and bioprocess engineering principles of wastewater treatment science and technology with deeper insight, advanced knowledge and greater confidence built on stronger competence.




Metal Ions in Biological Systems, Volume 43 - Biogeochemical Cycles of Elements


Book Description

Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemis




Metallomics: A Primer Of Integrated Biometal Sciences


Book Description

Metallomics is an integrated biometal science as it unifies different disciplines into a mainstream subject that can be taught to students of the biological and biomedical sciences. Metallomics bridges chemistry and the biological sciences from a global and quantitative systems approach, while the biological context provides new insights into the functions of metals in biological cells. The book challenges the traditional view of relating biochemistry only to organic chemistry, and discusses the structure and function of metal ions in the context of their environment in organisms.This is an essential read for undergraduate and graduate students in the fields of biochemistry, cell biology, nutrition (trace element research), toxicology, pharmacology and ecology.




The Responses of Marine Microorganisms, Communities and Ecofunctions to Environmental Gradients


Book Description

Marine environments are fluid. Microorganisms living in the ocean experience diverse environmental changes over wide spatiotemporal scales. For microorganisms and their communities to survive and function in the ocean, they need to have the capacity to sense, respond to, adapt to and/or withstand periodic and sporadic environmental changes. This eBook collates a variety of recent research reports and theoretical discussions on the ecoenergetic strategies, community structure, biogeochemical and ecosystem functions as well as regulatory processes and mechanisms that marine microorganisms employ in response to environmental gradients and variations.




Environmental Bioinorganic Chemistry of Aquatic Microbial Organisms


Book Description

The Environmental Bioinorganic Chemistry of Aquatic Microbial Organisms describes the interactions between metals and aquatic prokaryotic and eukaryotic microorganisms in their environment. Metals influence microbial growth in the aquatic environment as they can be either toxic to aquatic microbes, if present at too high concentrations in the environment, or limiting, if bio-essential and present at very low concentrations. In turn, microorganisms influence the biogeochemical cycling of metals as they affect trace metal concentrations, distributions between particulate and dissolved phase, and chemical speciation. At the sub cellular level, metalloproteins are the catalysts driving many steps in the biogeochemical cycles of major elements such as carbon, nitrogen and sulfur. Metals thus provide a link between the abundance and activity of enzymes, the growth of microorganisms, and the biogeochemical cycles of major climate influencing elements. Furthermore, the evolution of the chemistry of aquatic environments and atmosphere has left its mark on the microbial proteome as a direct result of changes in the solubility of metals. The aquatic microbial metallome thus has the potential to reveal information about key biogeochemical processes, their spatial and seasonal occurrence, and also to reveal how the geochemical environment is shaping the microbial population itself. The aim of this Research Topic is to highlight recent advances in our understanding of how metals influence the activity of aquatic microbes, and how microbes influence the biogeochemical cycling of metals. Applications of techniques in proteomics, spectroscopy, mass spectrometry and genomics are all leading to a greater understanding of the interactions between the microbial metallome and the “aquatic metallome” and thus the influence of metals on the biogeochemical cycles of climatically important elements such as carbon, nitrogen and sulfur. Both reviews and original research on the occurrence and abundance of microbial metal proteins and peptides, the utilisation of metals by aquatic microbes, the influence of microbially produced exudates on metal speciation and the biogeochemical cycling, and the toxicity of metals to microbial organisms are welcome.




Metal-based Anticancer Agents


Book Description

Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.




Environmental Nexus Approach


Book Description

Environmental Nexus Approach: Management of Water, Waste, and Soil establishes linkages between environmental resources, such as water, waste, and soil, in order to facilitate sustainable management of these resources. It shows the nexus approach as a policy-relevant means of environmental management by focusing on integrated management of water, waste, and soil resources. It synthesizes interdisciplinary theory, concepts, definitions, models, and findings involved in complex global sustainability problem-solving, making it an essential guide and reference. It includes real-world examples and applications making the book accessible to a broader interdisciplinary readership. Features: Explores cutting-edge developments in the environmental nexus approach of water, waste, and soil. Introduces the key mechanisms regarding antibiotic resistance genes, microplastics, and other emerging contaminants in the water, waste, and soil nexus. Investigates the fate and behavior of heavy metals, polyaromatic hydrocarbons, plastics, and pesticides in soil systems and their risk assessment. Provides insights into the latest developments, current research perspectives, technology development, critical thinking, and societal requirements of the environmental nexus between water, waste, and soil. This book is aimed at graduate students and researchers in environmental science and engineering, environmental engineering, and waste management.