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Navigating Metabolism

Author : Navdeep Singh Chandel

Publisher :

Page : 0 pages

File Size : 21,37 MB

Release : 2015

Category : SCIENCE

ISBN : 9781621820406

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Book Description

"Metabolic pathways used to be "road maps" most biologists learned as undergraduates and then promptly forgot. Recent work has revealed how changes in metabolism are closely linked to many aspects of cell behavior and the development of cancer and other diseases. This book represents both a new look at metabolism and a refresher course. It surveys the major metabolic pathways, places these in biological context, and highlights the key control points that control cell behavior and can become dysregulated in disease"--



Biochemical Pathways

Author : Gerhard Michal

Publisher : John Wiley & Sons

Page : 420 pages

File Size : 27,2 MB

Release : 2013-03-06

Category : Science

ISBN : 1118656881

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Book Description

The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “... highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)



Metabolism at a Glance

Author : J. G. Salway

Publisher : John Wiley & Sons

Page : 147 pages

File Size : 48,7 MB

Release : 2017-02-06

Category : Medical

ISBN : 0470674717

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Book Description

Metabolism at a Glance presents a concise, illustrated summary of metabolism in health and disease. This essential text is progressively appropriate for introductory through to advanced medical and biochemistry courses. It also provides a succinct review of inborn errors of metabolism, and reference for postgraduate medical practitioners and biomedical scientists who need a resource to quickly refresh their knowledge. Fully updated and extensively illustrated, this new edition of Metabolism at a Glance is now in full colour throughout, and includes new coverage of sports biochemistry; the metabolism of lipids, carbohydrates and cholesterol; glyceroneogenesis, α-oxidation and ω-oxidation of fatty acids. It also features the overlooked “Krebs Uric Acid Cycle”. Metabolism at a Glance offers an accessible introduction to metabolism, and is ideal as a revision aid for students preparing for undergraduate and USMLE Step 1 exams.



Metabolic Structure and Regulation

Author : Raymond S. Ochs

Publisher : CRC Press

Page : 302 pages

File Size : 14,52 MB

Release : 2017-12-14

Category : Medical

ISBN : 1315355809

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Book Description

There is a renewed interest in the fundamentals of energy metabolism, yet most people base their understanding on the views of generalists expressed in elementary textbooks. New techniques that enable analysis of thousands of metabolites provide useful data, but do not themselves substitute for an understanding of the fundamentals of metabolism. While classical ideas of metabolism are also valuable, some earlier ideas have not withstood further investigation. This book presents a personal philosophy but rests on what is broadly accepted by metabolic biochemists over the past few decades.



Functional Metabolism

Author : Kenneth B. Storey

Publisher : John Wiley & Sons

Page : 640 pages

File Size : 23,44 MB

Release : 2005-02-25

Category : Science

ISBN : 0471675571

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Book Description

Functional Metabolism of Cells is the first comprehensive survey of metabolism, offering an in-depth examination of metabolism and regulation of carbohydrates, lipids, and amino acids. It provides a basic background on metabolic regulation and adaptation as well as the chemical logic of metabolism, and covers the interrelationship of metabolism to life processes of the whole organism. The book lays out a structured approach to the metabolic basis of disease, including discussion of the normal pathways of metabolism, altered pathways leading to disease, and use of molecular genetics in diagnosis and treatment of disease. It also takes a unique comparative approach in which human metabolism is a reference for metabolism in microorganisms and plant design, and presents novel coverage of development and aging, and human health and animal adaptation. The final chapter reviews the past and future promise of new genetic approaches to treatment and bioinformatics. This, the most exhaustive treatment of metabolism currently available, is a useful text for advanced undergraduates and graduates in biochemistry, cell/molecular biology, and biomedicine, as well as biochemistry instructors and investigators in related fields.



The Heterogeneity of Cancer Metabolism

Author : Anne Le

Publisher : Springer

Page : 186 pages

File Size : 14,3 MB

Release : 2018-06-26

Category : Medical

ISBN : 331977736X

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Book Description

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.



Human Drug Metabolism

Author : Michael D. Coleman

Publisher : John Wiley & Sons

Page : 360 pages

File Size : 32,46 MB

Release : 2010-03-30

Category : Science

ISBN : 9780470689349

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Book Description

Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences. Completely revised and updated throughout, the new edition focuses only on essential chemical detail and includes patient case histories to illustrate the clinical consequences of changes in drug metabolism and its impact on patient welfare. After underlining the relationship between efficacy, toxicity and drug concentration, the book then considers how metabolizing systems operate and how they impact upon drug concentration, both under drug pressure and during inhibition. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained. The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs.



Navigating Eating Disorders: Unraveling the Complexities of Body, Mind, and Society

Author : Dr. Spineanu Eugenia

Publisher : Dr. Spineanu Eugenia

Page : 150 pages

File Size : 21,82 MB

Release : 2024-09-19

Category : Psychology

ISBN :

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Book Description

Dive into the intricate world of eating disorders with 'Navigating Eating Disorders: Unraveling the Complexities of Body, Mind, and Society.' This comprehensive treatise delves deep into the multifaceted nature of eating disorders, shedding light on the intricate interplay between societal influences, psychological factors, and physiological mechanisms. From the cultural pressures shaping body image to the neurobiological underpinnings of appetite regulation, this guide offers an in-depth exploration of the myriad factors contributing to these complex conditions. Discover the pivotal role of social and cultural norms in shaping perceptions around food and body image, while unraveling the psychological intricacies that underlie disordered eating behaviors. Explore the latest advancements in neurobiology, genetics, and behavioral sciences, providing a nuanced understanding of how the brain and genetics influence these disorders. This treatise doesn't just dissect the problem—it offers solutions. From evidence-based treatments and therapies to societal interventions and support strategies, it navigates the landscape of prevention, diagnosis, and comprehensive care. Gain insights into personalized treatments, the impact of family dynamics, and the role of societal awareness in reshaping attitudes toward body image and self-worth.



The Social Metabolism

Author : Manuel González de Molina

Publisher : Springer

Page : 368 pages

File Size : 46,87 MB

Release : 2014-06-30

Category : History

ISBN : 3319063588

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Book Description

Over this last decade, the concept of Social Metabolism has gained prestige as a theoretical instrument for the required analysis, to such an extent that there are now dozens of researchers, hundreds of articles and several books that have adopted and use this concept. However, there is a great deal of variety in terms of definitions and interpretations, as well as different methodologies around this concept, which prevents the consolidation of a unified field of new knowledge. The fundamental aim of the book is to conduct a review of the past and present usage of the concept of social metabolism, its origins and history, as well as the main currents or schools that exist around this concept. At the same time, the reviews and discussions included are used by the authors as starting points to draw conclusions and propose a theory of socio-ecological transformations. The theoretical and methodological innovations of this book include a distinction of two types of metabolic processes: tangible and intangible; the analysis of the social metabolism at different scales (in space and time) and a theory of socio-ecological change overcoming the merely “systemic” or “cybernetic” nature of conventional approaches, giving special protagonism to collective action.



Nutrient Metabolism

Author : Martin Kohlmeier

Publisher : Academic Press

Page : 899 pages

File Size : 50,34 MB

Release : 2015-05-12

Category : Technology & Engineering

ISBN : 0123877881

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Book Description

Nutrient Metabolism, Second Edition, provides a comprehensive overview of the supply and use of nutrients in the human body and how the body regulates intake. Chapters detail the principles determining digestion and absorption of food ingredients and how these compounds and their metabolites get into the brain, cross the placenta and pass through the kidneys. Each nutrient’s coverage contains a nutritional summary that describes its function, its food sources, dietary requirements, potential health risks if deficient, and impact of excessive intake. This handbook contains the latest information on the scope of structures, processes, genes and cofactors involved in maintaining a healthy balance of nutrient supplies. Of interest to a wide range of professionals because nutrient issues connect to so many audiences, the book contains a useful link to dietary supplements. Latest research findings on health and clinical effects of nutrients and of interventions affecting nutrient supply or metabolism Each nutrient covered contains a nutritional summary describing its function, food sources, dietary requirements, potential health risks if deficient, and impact of excessive intake. Nutrient information immediately accessible--from source to effect--in one volume