OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method


Book Description

The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...




OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 428: Skin Absorption: In Vitro Method


Book Description

This Test method has been designed to provide information on absorption of a test substance, (ideally radiolabelled), applied to the surface of a skin sample separating the two chambers (a donor chamber and a receptor chamber) of a diffusion cell ...













OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Descriptions of Selected Key Generic Terms used in Chemical Hazard/Risk Assessment


Book Description

This paper presents internationally harmonised generic and technical terms used in chemical hazard/risk assessment which will help facilitate the mutual use and acceptance of the assessment of chemicals between countries.







OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Reporting Summary Information on Environmental, Occupational and Consumer Exposure


Book Description

This document contains guidance for using the summary exposure information reporting formats, which were developed by the OECD Ad Hoc Group on Reporting Summary Exposure Information.




OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Environmental Persistence and Long Range Transport in the Context of PBTS/POPS Assessment


Book Description

This document contains the report from the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Persistence and Long-range Transport in the Context of PBTs/POPs Assessment, held on 29-31 October 2001 in Ottawa, Canada, together ...




Test No. 489: In Vivo Mammalian Alkaline Comet Assay


Book Description

The in vivo alkaline single cell gel electrophoresis assay, also called alkaline Comet Assay is a method measuring DNA strand breaks in eukaryotic cells.