Environmental Epigenetics


Book Description

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.




Evolution


Book Description

This text is about the central role of evolution in shaping the nature and diversity of the living world. It describes the processes of natural selection, how adaptations arise, and how new species form, as well as summarizing the evidence for evolution




A Biologist's Guide to Mathematical Modeling in Ecology and Evolution


Book Description

Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available




Systematics and the Origin of Species, from the Viewpoint of a Zoologist


Book Description

This study, first published in 1942, helped to revolutionize evolutionary biology by offering a new approach to taxonomic principles, and correlating the ideas and findings of modern systematics with those of other life disciplines. This book is one of the foundational documents of the Evolutionary Synthesis. It is the book in which Ernst Mayr pioneered his concept of species based chiefly on such biological factors as interbreeding and reproductive isolation, taking into account ecology, geography and life history. In the introduction to this edition, Mayr reflects on the place of this work in the subsequent history of his field.




The Oxford Handbook of Language Evolution


Book Description

Leading scholars present critical accounts of every aspect of the field, including work in animal behaviour; anatomy, genetics and neurology; the prehistory of language; the development of our uniquely linguistic species; and language creation, transmission, and change.




Microbial Evolution


Book Description

Bacteria have been the dominant forms of life on Earth for the past 3.5 billion years. They rapidly evolve, constantly changing their genetic architecture through horizontal DNA transfer and other mechanisms. Consequently, it can be difficult to define individual species and determine how they are related. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines how bacteria and other microbes evolve, focusing on insights from genomics-based studies. Contributors discuss the origins of new microbial populations, the evolutionary and ecological mechanisms that keep species separate once they have diverged, and the challenges of constructing phylogenetic trees that accurately reflect their relationships. They describe the organization of microbial genomes, the various mutations that occur, including the birth of new genes de novo and by duplication, and how natural selection acts on those changes. The role of horizontal gene transfer as a strong driver of microbial evolution is emphasized throughout. The authors also explore the geologic evidence for early microbial evolution and describe the use of microbial evolution experiments to examine phenomena like natural selection. This volume will thus be essential reading for all microbial ecologists, population geneticists, and evolutionary biologists.




Evidence and Evolution


Book Description

How should the concept of evidence be understood? And how does the concept of evidence apply to the controversy about creationism as well as to work in evolutionary biology about natural selection and common ancestry? In this rich and wide-ranging book, Elliott Sober investigates general questions about probability and evidence and shows how the answers he develops to those questions apply to the specifics of evolutionary biology. Drawing on a set of fascinating examples, he analyzes whether claims about intelligent design are untestable; whether they are discredited by the fact that many adaptations are imperfect; how evidence bears on whether present species trace back to common ancestors; how hypotheses about natural selection can be tested, and many other issues. His book will interest all readers who want to understand philosophical questions about evidence and evolution, as they arise both in Darwin's work and in contemporary biological research.




The Handbook of Historical Economics


Book Description

The Handbook of Historical Economics guides students and researchers through a quantitative economic history that uses fully up-to-date econometric methods. The book's coverage of statistics applied to the social sciences makes it invaluable to a broad readership. As new sources and applications of data in every economic field are enabling economists to ask and answer new fundamental questions, this book presents an up-to-date reference on the topics at hand. Provides an historical outline of the two cliometric revolutions, highlighting the similarities and the differences between the two Surveys the issues and principal results of the "second cliometric revolution" Explores innovations in formulating hypotheses and statistical testing, relating them to wider trends in data-driven, empirical economics




Population Genetics, Molecular Evolution, and the Neutral Theory


Book Description

One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.




How Evolution Shapes Our Lives


Book Description

" It is easy to think of evolution as something that happened long ago, or that occurs only in "nature," or that is so slow that its ongoing impact is virtually nonexistent when viewed from the perspective of a single human lifetime. But we now know that when natural selection is strong, evolutionary change can be very rapid. In this book, some of the world's leading scientists explore the implications of this reality for human life and society. With some twenty-five essays, this volume provides authoritative yet accessible explorations of why understanding evolution is crucial to human life--from dealing with climate change and ensuring our food supply, health, and economic survival to developing a richer and more accurate comprehension of society, culture, and even what it means to be human itself. Combining new essays with ones revised and updated from the acclaimed Princeton Guide to Evolution, this collection addresses the role of evolution in aging, cognition, cooperation, religion, the media, engineering, computer science, and many other areas. The result is a compelling and important book about how evolution matters to humans today. The contributors include Francisco J. Ayala, Dieter Ebert, Elizabeth Hannon, Richard E. Lenski, Tim Lewens, Jonathan B. Losos, Jacob A. Moorad, Mark Pagel, Robert T. Pennock, Daniel E. L. Promislow, Robert C. Richardson, Alan R. Templeton, and Carl Zimmer."--