Particle Characterization: Light Scattering Methods


Book Description

Particle characterization is an important component in product research and development, manufacture, and quality control of particulate materials and an important tool in the frontier of sciences, such as in biotechnology and nanotechnology. This book systematically describes one major branch of modern particle characterization technology - the light scattering methods. This is the first monograph in particle science and technology covering the principles, instrumentation, data interpretation, applications, and latest experimental development in laser diffraction, optical particle counting, photon correlation spectroscopy, and electrophoretic light scattering. In addition, a summary of all major particle sizing and other characterization methods, basic statistics and sample preparation techniques used in particle characterization, as well as almost 500 latest references are provided. The book is a must for industrial users of light scattering techniques characterizing a variety of particulate systems and for undergraduate or graduate students who want to learn how to use light scattering to study particular materials, in chemical engineering, material sciences, physical chemistry and other related fields.




Particle Size Analysis


Book Description

Particle Size Analysis reviews the development of particle characterization over the past 25 years and also speculates on its future. Interest in the subject has increased enormously over the years and this book highlights the changes and advances made within the field. This book is comprehensive in its coverage of particle size analysis and includes contributions on such characterization techniques as microscopy using fractal analysis, light diffraction, light scattering with the phase doppler technique, light observation, and photon correlation spectroscopy. A number of chapters address the interest in on-line in-stream particle size analysis and illustrate the progress being made in achieving this long sought after ideal of in-situ in-process particle characterization. Applications to other technological fields are detailed by chapters covering biological systems and the pharmaceutical industry. The subject of surface area determination is considered with particular emphasis on the measurements on porosity of powders, the characterization and comparability of reference materials, and the need for standards. Particle Size Analysis should provide stimulating reading for technologists, scientists, and engineers involved in particle characterization and powder technology worldwide.




Particle Size Measurements


Book Description

This book focuses on the practical aspects of particle size measurement: a major difference with existing books, which have a more theoretical approach. Of course, the emphasis still lies on the measurement techniques. For optimum application, their theoretical background is accompanied by quantitative quality aspects, limitations and problem identification. In addition the book covers the phenomena of sampling and dispersion of powders, either of which may be dominant in the overall analysis error. Moreover, there are chapters on the general aspects of quality for particle size analysis, quality management, reference materials and written standards, in- and on-line measurement, definitions and multilingual terminology, and on the statistics required for adequate interpretation of results. Importantly, a relation is made to product performance, both during processing as well as in final application. In view of its set-up, this book is well suited to support particle size measurement courses.




Light Scattering by Particles in Water


Book Description

Light scattering-based methods are used to characterize small particles suspended in water in a wide range of disciplines ranging from oceanography, through medicine, to industry. The scope and accuracy of these methods steadily increases with the progress in light scattering research. This book focuses on the theoretical and experimental foundations of the study and modeling of light scattering by particles in water and critically evaluates the key constraints of light scattering models. It begins with a brief review of the relevant theoretical fundamentals of the interaction of light with condensed matter, followed by an extended discussion of the basic optical properties of pure water and seawater and the physical principles that explain them. The book continues with a discussion of key optical features of the pure water/seawater and the most common components of natural waters. In order to clarify and put in focus some of the basic physical principles and most important features of the experimental data on light scattering by particles in water, the authors employ simple models. The book concludes with extensive critical reviews of the experimental constraints of light scattering models: results of measurements of light scattering and of the key properties of the particles: size distribution, refractive index (composition), structure, and shape. These reviews guide the reader through literature scattered among more than 210 scientific journals and periodicals which represent a wide range of disciplines. A special emphasis is put on the methods of measuring both light scattering and the relevant properties of the particles, because principles of these methods may affect interpretation and applicability of the results. The book includes extensive guides to literature on light scattering data and instrumentation design, as well as on the data for size distributions, refractive indices, and shapes typical of particles in natural waters. It also features a comprehensive index, numerous cross-references, and a reference list with over 1370 entries. An errata sheet for this work can be found at: http://www.tpdsci.com/Ref/Jonasz_M_2007_LightScatE.php *Extensive reference section provides handy compilations of knowledge on the designs of light scattering meters, sources of experimental data, and more *Worked exercises and examples throughout







Characterization of Pharmaceutical Nano- and Microsystems


Book Description

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.




Dynamic Light Scattering


Book Description

Lasers play an increasingly important role in a variety of detection techniques, making inelastic light scattering a tool of growing value in the investigation of dynamic and structural problems in chemistry, biology, and physics. Until the initial publication of this work, however, no monograph treated the principles behind current developments in the field.This volume presents a comprehensive introduction to the principles underlying laser light scattering, focusing on the time dependence of fluctuations in fluid systems; it also serves as an introduction to the theory of time correlation functions, with chapters on projection operator techniques in statistical mechanics. The first half comprises most of the material necessary for an elementary understanding of the applications to the study of macromolecules, or comparable sized particles in fluids, and to the motility of microorganisms. The study of collective (or many particle) effects constitutes the second half, including more sophisticated treatments of macromolecules in solution and most of the applications of light scattering to the study of fluids containing small molecules.With its wide-ranging discussions of the many applications of light scattering, this text will be of interest to research chemists, physicists, biologists, medical and fluid mechanics researchers, engineers, and graduate students in these areas.




Modern Methods of Particle Size Analysis


Book Description

Specialists in the field discuss the latest developments in particle size analysis, presenting an overview of state-of-the-art methodologies and data interpretation. Topics include commercial instrumentation, photon correlation spectroscopy, Fraunhofer Diffraction, field-flow fractionation, and detection systems for particle chromatography.




Characterization of Liquids, Nano- and Microparticulates, and Porous Bodies using Ultrasound


Book Description

Two key words define the scope of this book: 'ultrasound' and 'colloids'. Historically, there has been little real communication between practitioners in these two fields. Although there is a large body of literature devoted to ultrasound phenomenon in colloids, there is little recognition that such phenomena may be of real importance for both the development and applications of colloid science. On the other side, colloid scientists have not embraced acoustics as an important tool for characterizing colloids. The lack of any serious dialogue between these scientific fields is the biggest motivation behind this book. - Covers in detail this multidisciplinary field combining acoustics, electroacoustics, colloid science, analytical chemistry and rheology - Provides a bibliography with more than 1,000 references - Presents theories and their experimental verification, as well as analysis of the methods and hardware pertaining to applications such as pharmaceuticals, ceramics, and polymers




Optical Scattering


Book Description

The first edition of this book concentrated on relating scatter from optically smooth surfaces to the microroughness on those surfaces. After spending six years in the semiconductor industry, Dr. Stover has updated and expanded the third edition. Newly included are scatter models for pits and particles as well as the use of wafer scanners to locate and size isolated surface features. New sections cover the multimillion-dollar wafer scanner business, establishing that microroughness is the noise, not the signal, in these systems. Scatter measurements, now routinely used to determine whether small-surface features are pits or particles and inspiring new technology that provides information on particle material, are also discussed. These new capabilities are now supported by a series of international standards, and a new chapter reviews those documents. New information on scatter from optically rough surfaces has also been added. Once the critical limit is exceeded, scatter cannot be used to determine surface-roughness statistics, but considerable information can still be obtained - especially when measurements are made on mass-produced products. Changes in measurement are covered, and the reader will find examples of scatter measurements made using a camera for a fraction of the cost and in a fraction of the time previously possible. The idea of relating scatter to surface appearance is also discussed, and appearance has its own short chapter. After all, beauty is in the eye of the beholder, and what we see is scattered light.