Personalizing Asthma Management for the Clinician


Book Description

Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. - Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. - Prepares you to meet your patients' needs regarding asthma exacerbation prevention and asthma prevention. - Consolidates today's available information and guidance in this timely area into one convenient resource.




Severe Asthma


Book Description

This book presents state of the art knowledge on severe asthma with the aim of providing readers with a clear understanding of, first, the heterogeneity of the condition and of patients’ symptom profiles and responses to therapy and, second, the future implications of this heterogeneity for individualized patient care. After an opening section that offers an overview of severe asthma, including its clinical significance, the pathogenesis, available diagnostic approaches, and treatment options are described in detail. The sections on diagnosis and treatment cover the role of biomarkers, the use of radiologic diagnostic modalities, and both pharmacologic and non-pharmacologic therapies, including emerging options that will address hitherto unmet needs of patients. The outcomes of cutting-edge preclinical and clinical research are carefully documented and numerous useful tips provided on patient management. The inclusion of many informative schematic figures will assist readers in grasping the contents easily. The book will be of high value for medical students, researchers, general physicians, specialists, and paramedical staff.




Asthma


Book Description

Asthma: A Clinician's Guide incorporates the new National Heart Lung and Blood Institute's 2007 Guidelines for the Diagnosis and Management of Asthma (EPR-3) and emphasizes the importance of asthma control that has come to the forefront of asthma management. This vital text discusses the current data on genetics and strategies to overcome treatment disparities. With concise, evidence-based information in an easily accessible format, this book provides respiratory and pulmonary medicine students with a fundamental resource to better understand asthma and manage appropriate treatment for various patient populations. • Each chapter includes an outline, objectives, and key terms with definitions • Appendices include travel charts and school plans • Guideline-based step management algorithms provided for each age group • Peak flow charts and instruction guides are included • Forms/templates provided for reproduction This user-friendly text is an essential reference for students and clinicians alike!




Personalized Digital Phenotype Score, Healthcare Management and Intervention Strategies Using Knowledge Enabled Digital Health Framework for Pediatric Asthma


Book Description

Asthma is a personalized, and multi-trigger respiratory condition which requires continuous monitoring and management of symptoms and medication adherence. We developed kHealth: Knowledge-enabled Digital Healthcare Framework to monitor and manage the asthma symptoms, medication adherence, lung function, daily activity, sleep quality, indoor, and outdoor environmental triggers of pediatric asthma patients. The kHealth framework collects up to 1852 data points per patient per day. It is practically impossible for the clinicians, parents, and the patient to analyze this vast amount of multimodal data collected from the kHealth framework. In this chapter, we describe the personalized scores, clinically relevant asthma categorization using digital phenotype score, actionable insights, and potential intervention strategies for better pediatric asthma management.




Asthma


Book Description

As the series title implies each Clinician's Desk Reference is a practical resource and a daily aid for physicians in the hospital setting and in primary care.Asthma is one of the most important chronic disorders in the developed world. Evidence from around the world shows the prevalence of asthma has increased considerably since 1975, and now affe




KBot


Book Description

Asthma, chronic pulmonary disease, is one of the major health issues in the United States. Given its chronic nature, the demand for continuous monitoring of patient's adherence to the medication care plan, assessment of their environment triggers, and management of asthma control level can be challenging in traditional clinical settings and taxing on clinical professionals. A shift from a reactive to a proactive asthma care can improve health outcomes and reduce expenses. On the technology spectrum, smart conversational systems and Internet-of-Things (IoTs) are rapidly gaining popularity in the healthcare industry. By leveraging such technological prevalence, it is feasible to design a system that is capable of monitoring asthmatic patients for a prolonged period and empowering them to manage their health better.In this thesis, we describe kBot, a knowledge-driven personalized chatbot system designed to continuously track medication adherence of pediatric asthmatic patients (age 8 to 15) and monitor relevant health and environmental data. The outcome is to help asthma patients self manage their asthma progression by generating trigger alerts and educate them with various self-management strategies. kBOT takes the form of an Android application with a frontend chat interface capable of conversing both text and voice-based conversations and a backend cloud-based server application that handles data collection, processing, and dialogue management. The domain knowledge component is pieced together from the Asthma and Allergy Foundation of America, Mayoclinic, and Verywell Health as well as our clinical collaborator. Whereas, the personalization aspect is derived from the patient's history of asthma collected from the questionnaires and day-to-day conversations. The system has been evaluated by eight asthma clinicians and eight computer science researchers for chatbot quality, technology acceptance, and system usability. kBOT achieved an overall technology acceptance score of greater than 8 on an 11-point Likert scale and a mean System Usability Score (SUS) greater than 80 from both evaluation groups.




Textbook of Allergy for the Clinician


Book Description

This is the second and updated version of the Textbook of Allergy for the Clinician. It is a unique book in the field of allergy. The uniqueness lies in the international character of the book with contributors representing both the East and West. This book represents the diversity of issues affecting patients in the specialty of allergy, asthma & immunology. There is some discussion of the basic mechanisms involved and extensive elaboration for the clinicians. This book will appeal to medical students, residents and fellows undergoing training as well as consultants in academic and clinical practice settings. The color plates, especially in the section on Aerobiology, will help in the interaction between the patient and consultant in identifying the plant or flora which is the causative factor. The differences and similarities between the Eastern and Western approaches in the practice of the specialty are being addressed for the first time in a book.




Approach Based on Phenotype and EndotypeAsthma Diagnosis and Management


Book Description

Asthma is a severe and growing threat affecting both children and adults in both developing and developed world, currently affecting approximately 8% of US population. It is becoming increasingly recognized as a syndrome constituted by airway obstruction, airway hyperresponsiveness, and airway inflammation with different causes, associated risk factors, and underlying pathophysiology. The advances in basic and clinical research of asthma have accelerated over the past 20 years with increasing diagnostic tools, especially biomarkers, that led to specific characterization of individual patient's asthma pathophysiology, or disease "phenotype" and "endotype," which allowed precision medicine therapies, including new asthma biologics. This book aims to update the paradigm shifts in precision medicine of asthma diagnosis and management, driven by underlying phenotypes or endotypes.




Severe Asthma


Book Description

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.




Clinical Practice Guidelines We Can Trust


Book Description

Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.