Physiology, Biophysics, and Biomedical Engineering


Book Description

Physiology, Biophysics and Biomedical Engineering provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena. It covers the physical phenomena of electricity, pressure, and flow along with the adaptation of the physics of the phenomena to the special conditions and constraints of biolog




Physics of the Human Body


Book Description

This book comprehensively addresses the physics and engineering aspects of human physiology by using and building on first-year college physics and mathematics. Topics include the mechanics of the static body and the body in motion, the mechanical properties of the body, muscles in the body, the energetics of body metabolism, fluid flow in the cardiovascular and respiratory systems, the acoustics of sound waves in speaking and hearing, vision and the optics of the eye, the electrical properties of the body, and the basic engineering principles of feedback and control in regulating all aspects of function. The goal of this text is to clearly explain the physics issues concerning the human body, in part by developing and then using simple and subsequently more refined models of the macrophysics of the human body. Many chapters include a brief review of the underlying physics. There are problems at the end of each chapter; solutions to selected problems are also provided. This second edition enhances the treatments of the physics of motion, sports, and diseases and disorders, and integrates discussions of these topics as they appear throughout the book. Also, it briefly addresses physical measurements of and in the body, and offers a broader selection of problems, which, as in the first edition, are geared to a range of student levels. This text is geared to undergraduates interested in physics, medical applications of physics, quantitative physiology, medicine, and biomedical engineering.




Quantitative Human Physiology


Book Description

Quantitative Human Physiology: An Introduction, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. - Winner of a 2018 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors Association - Features a quantitative approach that includes physical and chemical principles - Provides a more integrated approach from first principles, integrating anatomy, molecular biology, biochemistry and physiology - Includes clinical applications relevant to the biomedical engineering student (TENS, cochlear implants, blood substitutes, etc.) - Integrates labs and problem sets to provide opportunities for practice and assessment throughout the course NEW FOR THE SECOND EDITION - Expansion of many sections to include relevant information - Addition of many new figures and re-drawing of other figures to update understanding and clarify difficult areas - Substantial updating of the text to reflect newer research results - Addition of several new appendices including statistics, nomenclature of transport carriers, and structural biology of important items such as the neuromuscular junction and calcium release unit - Addition of new problems within the problem sets - Addition of commentary to power point presentations




Biomedical Signals and Sensors I


Book Description

This two-volume set focuses on the interface between physiologic mechanisms and diagnostic human engineering. Today numerous biomedical sensors are commonplace in clinical practice. The registered biosignals reflect mostly vital physiologic phenomena. In order to adequately apply biomedical sensors and reasonably interpret the corresponding biosignals, a proper understanding of the involved physiologic phenomena, their influence on the registered biosignals, and the technology behind the sensors is necessary. The first volume is devoted to the interface between physiologic mechanisms and arising biosignals, whereas the second volume is focussed on the interface between biosignals and biomedical sensors. The physiologic mechanisms behind the biosignals are described from the basic cellular level up to their advanced mutual coordination level during sleep. The arising biosignals are discussed within the scope of vital physiologic phenomena to foster their understanding and comprehensive analysis.




The Physiology of Bioelectricity in Development, Tissue Regeneration and Cancer


Book Description

Recent advances in technology have led to the unprecedented accuracy in measurements of endogenous electric fields around sites of tissue disruption. State-of-the-art molecular approaches demonstrate the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. New informat




Biophysics of the Failing Heart


Book Description

Subjects in the monograph “Biophysics of the Failing Heart” include state of the art chapters considering major biophysical mechanisms for why hearts responding to acquired or inherited stressors enter into maladaptive processes eventually leading to an inability of the heart to respond efficiently to hemodynamic loads especially during exercise. The chapters describe biophysical techniques that have been applied to determine the triggers for the heart failure process as well as the mechanisms for sustaining the disorders. These techniques include measurements of active and passive mechanical properties and hemodynamics at levels of organization ranging from molecules to hearts beating in situ. Biophysical concepts and approaches are also applied to determination of signaling and signal transduction, energetics, ionic currents, transport processes, electro-chemical and chemo-mechanical coupling. By its emphasis on biophysical aspects of a prevalent clinical condition, the monograph is unique in its perspective and focus. The breadth of information in the chapters all in one place will be of value to clinicians and researchers at all levels. Modern research approaches and clinical understanding of heart failure demands integration of multiple aspects of the disorders. In most cases, combinations of clinician scientists and researchers author the chapters. A main benefit of the book is couched in its didactic approach together with its emphasis on how biophysical concepts and techniques aid in diagnosis and development of new therapies.




Signals and Systems in Biomedical Engineering


Book Description

In the past few years Biomedical Engineering has received a great deal of attention as one of the emerging technologies in the last decade and for years to come, as witnessed by the many books, conferences, and their proceedings. Media attention, due to the applications-oriented advances in Biomedical Engineering, has also increased. Much of the excitement comes from the fact that technology is rapidly changing and new technological adventures become available and feasible every day. For many years the physical sciences contributed to medicine in the form of expertise in radiology and slow but steady contributions to other more diverse fields, such as computers in surgery and diagnosis, neurology, cardiology, vision and visual prosthesis, audition and hearing aids, artificial limbs, biomechanics, and biomaterials. The list goes on. It is therefore hard for a person unfamiliar with a subject to separate the substance from the hype. Many of the applications of Biomedical Engineering are rather complex and difficult to understand even by the not so novice in the field. Much of the hardware and software tools available are either too simplistic to be useful or too complicated to be understood and applied. In addition, the lack of a common language between engineers and computer scientists and their counterparts in the medical profession, sometimes becomes a barrier to progress.




Medical Physics and Biomedical Engineering


Book Description

Medical Physics and Biomedical Engineering provides broad coverage appropriate for senior undergraduates and graduates in medical physics and biomedical engineering. Divided into two parts, the first part presents the underlying physics, electronics, anatomy, and physiology and the second part addresses practical applications. The structured approach means that later chapters build and broaden the material introduced in the opening chapters; for example, students can read chapters covering the introductory science of an area and then study the practical application of the topic. Coverage includes biomechanics; ionizing and nonionizing radiation and measurements; image formation techniques, processing, and analysis; safety issues; biomedical devices; mathematical and statistical techniques; physiological signals and responses; and respiratory and cardiovascular function and measurement. Where necessary, the authors provide references to the mathematical background and keep detailed derivations to a minimum. They give comprehensive references to junior undergraduate texts in physics, electronics, and life sciences in the bibliographies at the end of each chapter.




Introduction to Biomedical Engineering


Book Description

Under the direction of John Enderle, Susan Blanchard and Joe Bronzino, leaders in the field have contributed chapters on the most relevant subjects for biomedical engineering students. These chapters coincide with courses offered in all biomedical engineering programs so that it can be used at different levels for a variety of courses of this evolving field. Introduction to Biomedical Engineering, Second Edition provides a historical perspective of the major developments in the biomedical field. Also contained within are the fundamental principles underlying biomedical engineering design, analysis, and modeling procedures. The numerous examples, drill problems and exercises are used to reinforce concepts and develop problem-solving skills making this book an invaluable tool for all biomedical students and engineers. New to this edition: Computational Biology, Medical Imaging, Genomics and Bioinformatics.* 60% update from first edition to reflect the developing field of biomedical engineering* New chapters on Computational Biology, Medical Imaging, Genomics, and Bioinformatics* Companion site: http://intro-bme-book.bme.uconn.edu/* MATLAB and SIMULINK software used throughout to model and simulate dynamic systems* Numerous self-study homework problems and thorough cross-referencing for easy use




Chemical Biophysics


Book Description

Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.




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