Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine


Book Description

This book contains a selection of communications presented at the Third International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, held 4-6 July 1995 at Domaine d' Aix-Marlioz, Aix-Ies-Bains, France. This nice resort provided an inspiring environment to hold discussions and presentations on new and developing issues. Roentgen discovered X-ray radiation in 1895 and Becquerel found natural radioactivity in 1896 : a hundred years later, this conference was focused on the applications of such radiations to explore the human body. If the physics is now fully understood, 3D imaging techniques based on ionising radiations are still progressing. These techniques include 3D Radiology, 3D X-ray Computed Tomography (3D-CT), Single Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET). Radiology is dedicated to morphological imaging, using transmitted radiations from an external X-ray source, and nuclear medicine to functional imaging, using radiations emitted from an internal radioactive tracer. In both cases, new 3D tomographic systems will tend to use 2D detectors in order to improve the radiation detection efficiency. Taking a set of 2D acquisitions around the patient, 3D acquisitions are obtained. Then, fully 3D image reconstruction algorithms are required to recover the 3D image of the body from these projection measurements.




Computational Radiology and Imaging


Book Description

The articles collected in this volume are based on lectures given at the IMA Workshop, "Computational Radiology and Imaging: Therapy and Diagnostics", March 17-21, 1997. Introductory articles by the editors have been added. The focus is on inverse problems involving electromagnetic radiation and particle beams, with applications to X-ray tomography, nuclear medicine, near-infrared imaging, microwave imaging, electron microscopy, and radiation therapy planning. Mathematical and computational tools and models which play important roles in this volume include the X-ray transform and other integral transforms, the linear Boltzmann equation and, for near-infrared imaging, its diffusion approximation, iterative methods for large linear and non-linear least-squares problems, iterative methods for linear feasibility problems, and optimization methods. The volume is intended not only for mathematical scientists and engineers working on these and related problems, but also for non-specialists. It contains much introductory expository material, and a large number of references. Many unsolved computational and mathematical problems of substantial practical importance are pointed out.




The Theory and Practice of 3D PET


Book Description

The application of 3D methodology has recently been receiving increasing attention at many PET centres, and this monograph is an attempt to provide a state-of-the-art review of this methodology, covering 3D reconstruction methods, quantitative procedures, current tomography performance, and clinical and research applications. No such review has been available until now to assist PET researchers in understanding and implementing 3D methodology, and in evaluating the performance of the available imaging technology. In all the chapters, the subject matter is treated in sufficient depth to appeal equally to the physicist or engineer who wishes to establish the methodology, and to PET investigators with experience in 2D PET who wish to familiarize themselves with the concepts and advantages of 3D, and to be made aware of the pitfalls.




Inherently Parallel Algorithms in Feasibility and Optimization and their Applications


Book Description

The Haifa 2000 Workshop on "Inherently Parallel Algorithms for Feasibility and Optimization and their Applications" brought together top scientists in this area. The objective of the Workshop was to discuss, analyze and compare the latest developments in this fast growing field of applied mathematics and to identify topics of research which are of special interest for industrial applications and for further theoretical study.Inherently parallel algorithms, that is, computational methods which are, by their mathematical nature, parallel, have been studied in various contexts for more than fifty years. However, it was only during the last decade that they have mostly proved their practical usefulness because new generations of computers made their implementation possible in order to solve complex feasibility and optimization problems involving huge amounts of data via parallel processing. These led to an accumulation of computational experience and theoretical information and opened new and challenging questions concerning the behavior of inherently parallel algorithms for feasibility and optimization, their convergence in new environments and in circumstances in which they were not considered before their stability and reliability. Several research groups all over the world focused on these questions and it was the general feeling among scientists involved in this effort that the time has come to survey the latest progress and convey a perspective for further development and concerted scientific investigations. Thus, the editors of this volume, with the support of the Israeli Academy for Sciences and Humanities, took the initiative of organizing a Workshop intended to bring together the leading scientists in the field. The current volume is the Proceedings of the Workshop representing the discussions, debates and communications that took place. Having all that information collected in a single book will provide mathematicians and engineers interested in the theoretical and practical aspects of the inherently parallel algorithms for feasibility and optimization with a tool for determining when, where and which algorithms in this class are fit for solving specific problems, how reliable they are, how they behave and how efficient they were in previous applications. Such a tool will allow software creators to choose ways of better implementing these methods by learning from existing experience.










Clinical PET and PET/CT


Book Description

Clinical PET and PET/CT, 2nd Edition presents a valuable overview of the basic principles and clinical applications of PET and PET/CT. Emphasis is placed on the familiarization of normal distribution, artifacts, and common imaging agents such as FDG in conjunction with CT, MRI, and US to establish the clinical effectiveness of PET and PET/CT. Practical information about updated PET and PET/CT scanners, imaging processing, correlation, and quantification of PET and PET/CT measurements is also presented. This book is divided into two sections, the first half dealing with the basic principles of PET and PET/CT for instrumentation, fusion, radiopharmaceuticals, radiosynthesis, safety, and cost analysis. The second part of this volume presents chapters on the clinical techniques and applications of PET and PET/CT for common oncologic, cardiologic, and neurologic diseases. Numerous full color images provide comprehensive coverage on essential clinical PET and PET/CT studies.




Recent Studies on Risk Analysis and Statistical Modeling


Book Description

This book provides an overview of the latest developments in the field of risk analysis (RA). Statistical methodologies have long-since been employed as crucial decision support tools in RA. Thus, in the context of this new century, characterized by a variety of daily risks - from security to health risks - the importance of exploring theoretical and applied issues connecting RA and statistical modeling (SM) is self-evident. In addition to discussing the latest methodological advances in these areas, the book explores applications in a broad range of settings, such as medicine, biology, insurance, pharmacology and agriculture, while also fostering applications in newly emerging areas. This book is intended for graduate students as well as quantitative researchers in the area of RA.







Developments in Global Optimization


Book Description

In recent years global optimization has found applications in many interesting areas of science and technology including molecular biology, chemical equilibrium problems, medical imaging and networks. The collection of papers in this book indicates the diverse applicability of global optimization. Furthermore, various algorithmic, theoretical developments and computational studies are presented. Audience: All researchers and students working in mathematical programming.