Protein Phosphatase-1 Binding Motifs
Author : Paulina Wakula
Publisher : Leuven University Press
Page : 138 pages
File Size : 18,72 MB
Release : 2006
Category : Science
ISBN : 9789058675217
Author : Paulina Wakula
Publisher : Leuven University Press
Page : 138 pages
File Size : 18,72 MB
Release : 2006
Category : Science
ISBN : 9789058675217
Author : Sangdun Choi
Publisher : Springer
Page : 6330 pages
File Size : 11,6 MB
Release : 2017-12-15
Category : Medical
ISBN : 9781493968008
The second edition of this encyclopedia presents over 400 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities.
Author : Qiming Jin
Publisher : Leuven University Press
Page : 122 pages
File Size : 37,98 MB
Release : 2004
Category : Science
ISBN : 9789058673800
"This is a Ph.D. dissertation. This thesis deals with the eukaryotic protein NIPP1 (Nuclear Inhibitor of Protein Phosphate-1), which was initially described by the host laboratory in 1992 and still is the major focus of its research efforts. The first part of the introduction describes our current insights into the structure and function of NIPP1, with the exception of aspects that directly deal with this doctoral project. For reasons of clarity, the data are presented in a logical manner, which implies that they are not necessarily presented according to their order of discovery. In the final sections of the introduction, a brief overview will be given of the state of the art of the `structure and function of ribonucleases' and `transcriptional repression mechanisms,' two topics that directly related to this research project. Contents include: Introduction, The Structure and Function of NIPP1, The Structure and Function of Ribonucleases, Transcriptional Repression in Eukaryotes, Aims and Strategies, Materials and Methods, Results and Discussions, Mapping of the RNA-binding and Endoribonuclease Domain of NIPP1, Screening for Proteins that Interact with the C-Terminal domain of NIPP1."
Author : Greg Moorhead
Publisher : Springer Science & Business Media
Page : 390 pages
File Size : 41,45 MB
Release : 2008-02-05
Category : Science
ISBN : 159745267X
Protein Phosphatase Protocols presents a broad range of protocols for the study of protein phosphatases, all written by experts and innovators from phosphatase laboratories around the world. This volume is a compendium of resources for the study of protein phosphatases and their potential as drug targets. Experimental methodologies are taken from proteomics, bioinformatics, genomics, biochemistry, RNAi, and genetics.
Author : Ralph A. Bradshaw
Publisher : Academic Press
Page : 3188 pages
File Size : 28,97 MB
Release : 2009-11-03
Category : Science
ISBN : 0080920918
Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field
Author : Ashok K. Srivastava
Publisher : Springer Science & Business Media
Page : 206 pages
File Size : 21,98 MB
Release : 1998-05-31
Category : Science
ISBN : 9780792381136
In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.
Author :
Publisher :
Page : 0 pages
File Size : 37,68 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : Linda J. Van Eldik
Publisher : Academic Press
Page : 497 pages
File Size : 11,63 MB
Release : 2012-12-02
Category : Science
ISBN : 0080926363
Calmodulin and Signal Transduction focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. - Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes - Selected case studies and precedents related to molecular mechanisms - Protein-protein recognition between calmodulin and the enzymes it regulates - Cross-talk and interdigitation with other signal transduction pathways
Author : Monika Fuxreiter
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 12,31 MB
Release : 2012-03-07
Category : Medical
ISBN : 1461406595
Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered proteins in complex eukaryotic signaling networks. In this volume, Peter Tompa and Monika Fuxreiter have assembled a series of papers that address the issue of fuzziness in molecular interactions. These papers provide a broad overview of the phenomenon of fuzziness and provide compelling examples of the central role played by fuzzy interactions in regulation of cellular signaling processes and in viral infectivity. These contributions summarize the current state of knowledge in this new field and will undoubtedly stimulate future research that will further advance our understanding of fuzziness and its role in biomolecular interactions.
Author : Nahum Sonenberg
Publisher : CSHL Press
Page : 1034 pages
File Size : 33,62 MB
Release : 2001
Category : Gene expression
ISBN : 9780879696184
Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translation control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translation machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.