Quantitative Imaging for Clinical Decisions
Author : Nandita Maria deSouza
Publisher : Frontiers Media SA
Page : 124 pages
File Size : 13,1 MB
Release : 2022-08-19
Category : Medical
ISBN : 2889746763
Quantitative Magnetic Resonance Imaging
Author : Nicole Seiberlich
Publisher : Academic Press
Page : 1094 pages
File Size : 37,91 MB
Release : 2020-11-18
Category : Computers
ISBN : 0128170581
Book Description
Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Imaging Biomarkers
Author : Luis Martí-Bonmatí
Publisher : Springer
Page : 313 pages
File Size : 50,58 MB
Release : 2016-11-03
Category : Medical
ISBN : 3319435043
Book Description
This is the first book to cover all aspects of the development of imaging biomarkers and their integration into clinical practice, from the conceptual basis through to the technical aspects that need to be considered in order to ensure that medical imaging can serve as a powerful quantification instrument capable of providing valuable information on organ and tissue properties. The process of imaging biomarker development is considered step by step, covering proof of concept, proof of mechanism, image acquisition, image preparation, imaging biomarker analysis and measurement, detection of measurement biases (proof of principle), proof of efficacy and effectiveness, and reporting of results. Sources of uncertainty in the accuracy and precision of measurements and pearls and pitfalls in gold standards and biological correlation are discussed. In addition, practical use cases are included on imaging biomarker implementation in brain, oncologic, cardiovascular, musculoskeletal, and abdominal diseases. The authors are a multidisciplinary team of expert radiologists and engineers, and the book will be of value to all with an interest in the quantitative imaging of biomarkers in personalized medicine.
Quantitative Medical Image Analysis for Decision Support
Author : Jiajing Xu
Publisher :
Page : pages
File Size : 39,63 MB
Release : 2013
Category :
ISBN :
Book Description
A crucial challenge for radiology is maintaining high interpretation accuracy in the face of increasing imaging workload and limited time to review and interpret the images for each patient. Variation in interpretation accuracy among radiologists is a recognized challenge. Two techniques that could help radiologists improve their interpretation are Content-based Image Retrieval (CBIR) for diagnostic support, and lesion size tracking for evaluating response to treatment. CBIR provides assists radiologists to find images from a database that are similar in terms of shared imaging features to the images they are interpreting. The performance of CBIR hinges critically on features that characterize lesions. In the first half of the talk, I will focus on the development of a novel quantitative imaging feature that describes the margin characteristics of lesions. This new margin sharpness feature is robust to variation in lesion segmentation, and achieves excellent CBIR performance in clinical datasets. Tracking lesion size in response to treatment is a crucial component for patient management as well as towards finding the best cancer therapy through clinical trials. Traditionally, tracking lesion size using serial Computed Tomography (CT) scans is largely a manual and tedious process. In the second half of the talk, I will present a novel method to automatically track and segment lymph nodes in serial CT scans. My method has achieved excellent overall segmentation performance compared to manual segmentation provided by radiologists. Ultimately, I envision that the translation of both of the above methods to the clinic will improve diagnostic accuracy, precision, and efficiency.
Quantitative Imaging in Medicine
Author : Robert J. Nordstrom
Publisher :
Page : 170 pages
File Size : 40,52 MB
Release : 2021
Category : SCIENCE
ISBN : 9780735423466
Book Description
Quantitative Imaging in Medicine: Background and Basics presents the foundations and theoretical building blocks of a topic that is rapidly emerging as one of the most important in medical research and clinical imaging. This timely book provides a thorough introduction to the standards and tools of quantitative imaging. It is the first book-length compendium to address different imaging modalities focusing on the clinical adaption of novel imaging methods. This important book: -- Presents the history, clinical need, and clinical validation of quantitative imaging -- Integrates discussions of QIBA, RECIST, clinical pipelines, phantoms, site qualification, radiomics, and artificial intelligence -- Provides ample reference lists to guide readers to an even deeper understanding of this very broad topic Radiologists, oncologists, imaging scientists, and computer scientists will find this book invaluable. It also serves as a comprehensive resource for teaching the fundamentals to trainees in radiology, medical physics, and imaging studies. (Description taken from publisher website).
Handbook for Clinical Trials of Imaging and Image-Guided Interventions
Author : Nancy A. Obuchowski
Publisher : John Wiley & Sons
Page : 224 pages
File Size : 49,68 MB
Release : 2015-12-29
Category : Medical
ISBN : 1118849566
Book Description
Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.
Radiomics and Radiogenomics
Author : Ruijiang Li
Publisher : CRC Press
Page : 420 pages
File Size : 13,37 MB
Release : 2019-07-09
Category : Science
ISBN : 1351208268
Book Description
Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation
Medical Imaging
Author : Mostafa Analoui
Publisher : CRC Press
Page : 465 pages
File Size : 42,92 MB
Release : 2012-11-08
Category : Medical
ISBN : 1439871027
Book Description
The discovery of x-ray, as a landmark event, enabled us to see the "invisible," opening a new era in medical diagnostics. More importantly, it offered a unique undestanding around the interaction of electromagnetic signal with human tissue and the utility of its selective absorption, scattering, diffusion, and reflection as a tool for understanding the physiology, evolution of disease, and therapy. With contributions from world-class experts, Medical Imaging: Principles and Practices offers a review of key imaging modalities with established clinical utilization and examples of quantitative tools for image analysis, modeling, and interpretation. The book provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in Magnetic Resonance Microcopy, the physics of instrumentation and signal collection, and their application in clinical practice. Highlights include a chapter offering a unique perspective on the use of quantitative PET for its applications in drug discovery and development, which is rapidly becoming an indispensible tool for clinical and research applications, and a chapter addressing the key issues around organizing and searching multimodality data sets, an increasingly important yet challenging issue in clinical imaging. Topics include: X-ray imaging and computed tomography MRI and magnetic resonance microscopy Nuclear imaging Ultrasound imaging Electrical Impedance Tomography (EIT) Emerging technologies for in vivo imaging Contrast-enhanced MRI MR approaches for osteoarthritis and cardiovascular imaging PET quantitative imaging for drug development Medical imaging data mining and search The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community ofresearchers and practitioners.
Functional Neuromarkers for Psychiatry
Author : Juri D. Kropotov
Publisher : Academic Press
Page : 500 pages
File Size : 15,57 MB
Release : 2016-05-03
Category : Science
ISBN : 0124105203
Book Description
Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results. - Identifies specific brain activation patterns that are neuromarkers for psychiatric disorders - Includes neuromarkers as seen via fMRI, PET, qEEG, and ERPs - Addresses neuromarkers for ADHD, schizophrenia, and OCD in detail - Provides information on using neuromarkers for diagnosis and/or personalized treatment
Medical Imaging and Radiotherapy Research: Skills and Strategies
Author : Aarthi Ramlaul
Publisher : Springer Nature
Page : 427 pages
File Size : 18,88 MB
Release : 2020-03-23
Category : Medical
ISBN : 3030379442
Book Description
This exciting new book equips radiography students and practitioners with the key skills and strategies required to undertake research within medical imaging and radiotherapy and to disseminate the research findings effectively. Quantitative and qualitative research methods are covered, with guidance provided on the entire research process, from literature researching, information management and literature evaluation through to data collection, data analysis, and writing up. Attention is drawn to sampling errors and other potential sources of bias, and the conduct of randomized controlled trials, systematic reviews, and meta-analyses are clearly explained. Specific instruction is given on the structure and presentation of dissertations, writing journal articles for publication, and the dissemination of research findings at conferences. Information on patient and public involvement in research and research funding bodies are also provided with advice on how to maximize the likelihood of success when submitting applications for funding.
