Regulation of Mammalian Phosphoglycolate Phosphatase
Author : Daria Marie Engelmann
Publisher :
Page : 0 pages
File Size : 19,86 MB
Release : 2023
Category :
ISBN :
Author : Daria Marie Engelmann
Publisher :
Page : 0 pages
File Size : 19,86 MB
Release : 2023
Category :
ISBN :
Author : Daria Marie Engelmann
Publisher :
Page : 0 pages
File Size : 34,57 MB
Release : 2019
Category :
ISBN :
Author : Marlene Deluca
Publisher : Elsevier
Page : 536 pages
File Size : 10,21 MB
Release : 2014-06-28
Category : Science
ISBN : 148321723X
Current Topics in Cellular Regulation: Volume 24, Enzyme Catalysis and Control is a compendium of papers that discusses phosphoryl transfer reactions, the role of water on the free energy of hydrolysis of pyrophosphate, and the hormonal actions of vitamin D. Other papers describe the regulation lipid metabolism by a lipid-carrying protein, the GABA, and taurine enzymes in mammalian brain. One paper examines the role of vitamin D in the metabolism of cells, as well as in the whole animal. Upon absorption in the body, the vitamin undergoes various metabolic transformations before interacting with specific receptors, and then inducting the genome in the target tissues to generate biological and hormonal responses. Another paper notes the possibility of a genetic defect in cancer cells that results in the abnormal accumulation of sterol carrier protein (SCP) and cholesterol in vivo; and also in the inability to maintain levels of SCP or cholesterol in vitro. One paper shows that tartrate, or other organic acids, secreted into the medium by the penicillia keeps the pH in an optimal range for acid protease degradation of proteins and glycoproteins. This mechanism helps the fungus to survive in a nutrient environment (which is unbalanced with respect to an optimum C/N ratio and at a pH unfavorable to many bacteria and other life forms). Another paper proposes a model for the modulation of ATP synthetase activities and medium exchange reactions by energy input, substrate concentration, or others that affect the microenvironment of the enzyme under certain conditions. The compendium will prove beneficial to molecular biologists, general biologists, microbiologists, and biochemists.
Author : Damien Thévenin
Publisher : Springer Nature
Page : 321 pages
File Size : 49,26 MB
Release : 2024-01-27
Category : Science
ISBN : 1071635697
This second edition volume expands on the previous edition with discussions on the latest advancements in protein tyrosine phosphatases (PTP) research used to investigate these essential enzymes and new inhibitors. The new techniques covered in the chapters of this book include studying enzymes in vitro, in cells, and in animal models through proteomics, genomics, and structural biology. Furthermore, new advances in pharmacology and drug design have contributed to the developing novel therapeutics that target PTPs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Protein Tyrosine Phosphatases: Methods and Protocols, Second Edition is a valuable resource for both experienced and novel researchers in this field, and will lead to discoveries and accelerated progress in the field of PTP, signal transduction, and drug development.
Author : Pierre De Meyts
Publisher : Frontiers Media SA
Page : 148 pages
File Size : 47,84 MB
Release : 2023-04-14
Category : Medical
ISBN : 2832520812
Author :
Publisher :
Page : 1220 pages
File Size : 14,41 MB
Release : 1987
Category : Medicine
ISBN :
Author : Institute for Cancer Research (Philadelphia, Pa.)
Publisher :
Page : 268 pages
File Size : 11,22 MB
Release : 1982
Category : Cancer
ISBN :
Author : Angelos K. Sikalidis
Publisher : Frontiers Media SA
Page : 213 pages
File Size : 35,4 MB
Release : 2023-12-29
Category : Medical
ISBN : 2832542093
Author : Bernard L. Horecker
Publisher : Elsevier
Page : 316 pages
File Size : 13,29 MB
Release : 2014-06-28
Category : Science
ISBN : 1483217132
Current Topics in Cellular Regulation, Volume 14 reviews the advances in the general area of cellular regulation. This book discusses the mechanism and function of the C4 pathway, regulation of individual enzymes, inhibitors of isoleucine and valine biosynthesis, and patterns of derepression. The functions of 2,3-bisphosphoglycerate; 2,3-bisphosphoglycerate in erythrocytes during development; and regulation of glycogen synthetase activity are also elaborated. This publication likewise covers the substrate specificity of cAMP-dependent protein kinase, model systems of enzyme sequences, and posttranslational modifications in selected enzymes. This volume is a good source for biologists and researchers interested in the basic mechanisms involved in the regulation of diverse cellular activities.
Author :
Publisher :
Page : 674 pages
File Size : 40,58 MB
Release : 1996
Category : Genetics
ISBN :