Royal Inbreeding and Other Maladies


Book Description

When we think of kings and queens, we conjure up illusions of a magnificent kingdom where His and Her Majesties live in the lap of luxury and want for nothing. While this may be true, life wasn’t always as perfect. With the history of royal families comes a long and twisted history of genetics and family intermarriage that is often swept aside. In Ms Cummings' latest book, she takes us through the complicated spider’s web of royal marriages. She tells us of the atrocities of the Ptolemy Dynasty as they continued to marry brothers and sisters to fend off political outsiders. She tells us about the centuries of intermarriage in European’s most prominent royal family, along with the devastating results that came with it. We will learn of the devastation of mental illness that befell reigning monarchs of The Hundred Years War and plagued George III of England, Juana of Castile and the Wittlebach Empire. She will also tell us of the desperation that fell upon the Russian Royal Family as their only heir to the throne grew ill with haemophilia. She will also go into depth about the notorious Hapsburgs, the decades of physical and mental ailments that tormented them, and how their empire ended with the most inbred royal in history, Charles II of Spain. After hearing the heartwrenching stories of these great monarchs, you’ll find that you can’t help but sympathize with them as you read about how genetics was the ultimate game-changer in most families.




Royal Maladies


Book Description

An intensive historical study of the hereditary diseases hemophilia and porphyria in the personal and political lives of the European royal families Part I Nineteenth century medical knowledge of hemophilia as a hereditary bleeding disorder will be considered. Hemophilia appeared in a son born to Queen Victoria in 1853. Hemophilia was transmitted through Victoria’s unaffected daughters to the ruling houses in Germany, Russia and Spain. The political consequences of a chronically ill male heir to the throne fostered the demise of the royal families in these countries. The royal physicians were well aware of the hereditary nature of hemophilia and failed to advise the British royal family on this matter that had significant political consequences for the modern world. Part II The “Madness of King George III” resulted from variegate porphyria, an inherited disorder of heme metabolism. The disorder was evident in: The immediate family of George III, Ancestors from at least the 13th century, Descendents into the 20th century. The malady was inherited by other ruling houses in continental Europe and affected political life there for over six centuries. Genetic analysis will consider how such an anomaly could have been inherited through so many successive generations. Preliminary DNA evidence will be considered to document variegate porphyria in living relatives of the British royal family. Alternate history if these disorders had not plagued the royal families will be considered in conclusion.




Royal Inbreeding and Other Maladies


Book Description

When we think of kings and queens, we conjure up illusions of a magnificent kingdom where His and Her Majesties live in the lap of luxury and want for nothing. While this may be true, life wasn’t always as perfect. With the history of royal families comes a long and twisted history of genetics and family intermarriage that is often swept aside. In Ms Cummings' latest book, she takes us through the complicated spider’s web of royal marriages. She tells us of the atrocities of the Ptolemy Dynasty as they continued to marry brothers and sisters to fend off political outsiders. She tells us about the centuries of intermarriage in European’s most prominent royal family, along with the devastating results that came with it. We will learn of the devastation of mental illness that befell reigning monarchs of The Hundred Years War and plagued George III of England, Juana of Castile and the Wittlebach Empire. She will also tell us of the desperation that fell upon the Russian Royal Family as their only heir to the throne grew ill with haemophilia. She will also go into depth about the notorious Hapsburgs, the decades of physical and mental ailments that tormented them, and how their empire ended with the most inbred royal in history, Charles II of Spain. After hearing the heartwrenching stories of these great monarchs, you’ll find that you can’t help but sympathize with them as you read about how genetics was the ultimate game-changer in most families.







Risky Genes


Book Description

What does it mean to be told you have an increased risk of genetic breast cancer because you are of Ashkenazi Jewish origin? In a time of ever increasing knowledge about variations in genetic disease risk among different populations, there is a pressing need for research regarding the implications of such information for members of high-risk populations. With first hand, intimate descriptions of women's experiences of being Jewish and of being at increased risk of genetic breast cancer, this book offers new insight into the ongoing debates regarding the implications of genetic research for populations, and of new genetic knowledge for individual and collective identity.




Scientific American


Book Description




Uncle John's Endlessly Engrossing Bathroom Reader


Book Description

Strategically placed near the best seat in your home, Uncle John’s Endlessly Engrossing Bathroom Reader is jam-packed with great bathroom reading. It’s the gift that keeps on giving...and giving...and giving.... The BRI’s 22nd all-new edition--Uncle John’s Endlessly Engrossing Bathroom Reader--is like reading several books all rolled into one: a history book, a weird news anthology, a science text, a dictionary, a how-to manual, a sports magazine, a joke book…and the list goes on and on. Since 1987, the Bathroom Readers’ Institute has led the movement to stand up for those who sit down and read in the bathroom (and everywhere else for that matter). With more than 11 million books in print, the Uncle John’s Bathroom Reader series is the longest-running, most popular series of its kind in the world. Where else could you learn about the lost cloud people of Peru, the world’s first detective, and the history of surfing? Uncle John rules the world of information and humor, so get ready to be thoroughly entertained. Read all about… * Soda pop flops * Spider farms * England’s Secret UFO Files * Real hillbilly recipes * Webster’s least-wanted words * Super-trains * And much more!




Sharks upon the Land


Book Description

A study of colonialism and indigenous health in Hawaiʻi, highlighting cultural change over time.




Genetic Disorders Among Arab Populations


Book Description

Few regions of the world have a more varied physiography or a richer ethnic, religious, social, and cultural mix than the Arab world. As a consequence, Arabs are genetically diverse despite their linguistic and religious cohesion. High but variable rates of inbreeding prevail in all Arab countries with numerous examples of isolates among them. These include some Bedouin groups, Nubians, Druze, Jews, and others. Arab populations have high frequencies of autosomal recessive disorders, homozygosity of autosomal dominant and X-linked traits, and a wealth of new syndromes and variants, the majority of which are autosomal recessive. Genetic disorders that cause major health problems include hemoglobinopathies, neurogenetic disorders, inherited metabolic diseases, and inborn error of morphogenesis. Because of their characteristically high prevalence, some of these disorders are considered markers for Arab populations. This book presents the unique profile of genetic disorders and variants in Arabs. In addition, it describes their unusual demographic pattern including fertility rates and other population dimensions, family structure, magnitude and effects of consanguineous marriages and indicators of health and disease. Genetic counseling and the distinctive cultural and religious attitudes towards various genetic issues are also presented. Disorders that have increased tribal occurrences or are limited to large kindreds, as well as small geographic or religious isolates, are highlighted to facilitate their recognition, study, and management.




Bovine Medicine


Book Description

Bovine Medicine provides practical and comprehensive information oncattle disease and production and is a key reference for all largeanimal vets. Since the first edition was published in 1991 therehave been significant improvements in disease control andmanagement of cattle. Almost all parts of the book have beenupdated and completely rewritten. There are new chapters onsurgery, embryo transfer, artificial insemination, ethno-veterinarymedicine and biosecurity, and a new consolidating chapter on theinteraction between the animal, environment, management anddisease. The previous edition has sold all over the world, and as aresult of this a greater emphasis has been placed on conditions andtheir treatment in areas other than temperate regions. A newsection entitled "Global Variation in Cattle Practice" has beenincluded with contributors discussing bovine medicine practice intheir part of the world. All in all this is an outstanding resource for any practisingvet and an excellent reference for veterinary students.




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