Saliva: Secretion and Functions


Book Description

Health professionals are more and more aware of the importance of saliva for oral health and well-being. As saliva secretion is steadily compromised with advancing age, it becomes a factor of concern in societies with an aging population, especially with a growing number of people who keep their own teeth. The numerous functions of saliva, like antimicrobial activity, lubrication, wound healing and its role in taste experience are only truly recognized when saliva secretion is hampered. In medical diagnostics, saliva shows its value as a safe and economical alternative to blood. This publication provides a comprehensive overview of the latest developments in salivary research by some of the world’s leading experts in the field. Chapters deal with various aspects: anatomy and physiology, e.g. regeneration of salivary glands, saliva functions, e.g. its protective and rheological properties, and diagnostics and disorders, e.g. xerostomia and hypersalivation. This book is not only recommended to basic scientists working in the field of oral biology, but also to dental students, dentists and health professionals who want to know more about one of the most underestimated bodily fluids.




Defining Physiology: Principles, Themes, Concepts. Volume 2


Book Description

This second volume of Defining Physiology: Principles, Themes, Concepts. continues on the same format as the first. In this new release, a selection of 44 essential topics in each major organ system is defined, then major themes, concept and principles surrounding these words in their physiologic scenarios are elaborated. For each keyword, a question is posed at the end of the text to test for a better understanding of the associated physiology of nervous and gastrointestinal systems. This book presents an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.




Salivary Diagnostics


Book Description

Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.




Salivary Glands


Book Description

Saliva is a complex fluid that maintains oral health and has many physiological functions. It is a noninvasive diagnostic fluid as well. Lately, salivary diagnostics has proven its potential to reach clinical practice in the near future for the early detection, diagnosis, and monitoring of various diseases. Salivary Glands - New Approaches in Diagnostics and Treatment is a comprehensive reference, which brings together information on salivary secretion and its disorders, the novel salivary diagnostic methods for numerous diseases, and new techniques in the treatment of salivary diseases. This book contains information for a diverse audience, including dentists, oral biologists, experimental biologists, molecular biologists, oncologists, radiologists, oral and maxillofacial surgeons, and otorhinolaryngologists.




Glandular Mechanisms of Salivary Secretion


Book Description

Saliva is essential for oral health and influences all events in the mouth. A deficiency of saliva can have devastating consequences. Therefore, it is important to have a book about the basic tissue mechanisms involved in the secretion of saliva, based on an holistic approach. With such an aim in mind, this book contains chapters covering the histological basis for secretion, electrophysiological events, electrolyte and water secretion, protein synthesis and secretion, bloodflow, capillary dynamics, myoepithelial activity, glandular permeability, hormonal influences, including the effects of diabetes, and the synthesis and secretion of IgA in man. The chapters have been written by international experts in the field, who present balanced accounts of their subjects. The secretory mechanisms described in this book have a far-reaching impact beyond the salivary field and have applicability to all forms of exocrine secretion. Salivary glands offer many advantages for experimental study of these phenomena since they can be tested more precisely than most other glands, having ducts that can readily be cannulated for assessing the secretion. As a single-source of up-to-date data, this book will benefit doctors and dentists, and anyone interested in secretory phenomena, including physiologists, biochemists and cell biologists. It not only brings together all available data on this subject, as it stands at the turn of the century, but also lays down a sound platform of knowledge on which further investigations can be based.




Non-Motor Symptoms of Parkinson's Disease


Book Description

Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.




Neurorehabilitation Therapy and Therapeutics


Book Description

This practical handbook for clinicians covers pharmacological and non-pharmacological treatment options in neurological rehabilitation.




Advances in Salivary Diagnostics


Book Description

This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of “salivaomics” is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.




Oral Processing and Consumer Perception


Book Description

This is the first book for some years that provides a comprehensive overview of food oral processing including the biomechanics of swallowing, the biophysics of mouthfeel and texture as well as the biochemistry of flavours and how food microstructures can be manipulated.




Drug-Induced Oral Complications


Book Description

This book provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance. It will be of value for all dental and medical practitioners who encounter these complications in their clinical practice.




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