SARS- and Other Coronaviruses


Book Description

In 2003, the word "coronavirus" spread across the globe, somewhat further than the virus that sparked the panic. In this book, expert researchers examine these devastating viruses through 23 state-of-the-art, widely applicable protocols with minute detail. Comprehensive and cutting-edge, the book serves as an ideal guide for all virologists and especially for those working with coronaviruses. Written by international experts, this book is relevant to a wide array of professions.




Learning from SARS


Book Description

The emergence of severe acute respiratory syndrome (SARS) in late 2002 and 2003 challenged the global public health community to confront a novel epidemic that spread rapidly from its origins in southern China until it had reached more than 25 other countries within a matter of months. In addition to the number of patients infected with the SARS virus, the disease had profound economic and political repercussions in many of the affected regions. Recent reports of isolated new SARS cases and a fear that the disease could reemerge and spread have put public health officials on high alert for any indications of possible new outbreaks. This report examines the response to SARS by public health systems in individual countries, the biology of the SARS coronavirus and related coronaviruses in animals, the economic and political fallout of the SARS epidemic, quarantine law and other public health measures that apply to combating infectious diseases, and the role of international organizations and scientific cooperation in halting the spread of SARS. The report provides an illuminating survey of findings from the epidemic, along with an assessment of what might be needed in order to contain any future outbreaks of SARS or other emerging infections.




Coronaviruses


Book Description

Paperback. ISBN 978-1-912530-35-9. In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. Essential reading for all coronavirologists as well as scientists working on other viruses of the respiratory and/or gastrointestinal tract.




Molecular Biology of the SARS-Coronavirus


Book Description

SARS was the ?rst new plague of the twenty-?rst century. Within months, it spread worldwide from its “birthplace” in Guangdong Province, China, affecting over 8,000 people in 25 countries and territories across ?ve continents. SARS exposed the vulnerability of our modern globalised world to the spread of a new emerging infection. SARS (or a similar new emerging disease) could neither have spread so rapidly nor had such a great global impact even 50 years ago, and arguably, it was itself a product of our global inter-connectedness. Increasing af?uence and a demand for wild-game as exotic food led to the development of large trade of live animal and game animal markets where many species of wild and domestic animals were co-housed, providing the ideal opportunities for inter-species tra- mission of viruses and other microbes. Once such a virus jumped species and attacked humans, the increased human mobility allowed the virus the opportunity for rapid spread. An infected patient from Guangdong who stayed for one day at a hotel in Hong Kong led to the transmission of the disease to 16 other guests who travelled on to seed outbreaks of the disease in Toronto, Singapore, and Vietnam, as well as within Hong Kong itself. The virus exploited the practices used in modern intensive care of patients with severe respiratory disease and the weakness in infection control practices within our health care systems to cause outbreaks within hospitals, further amplifying the spread of the disease. Health-care itself has become a two-edged sword.




SARS Unmasked


Book Description

Severe Acute Respiratory Syndrome (SARS) was the first global pandemic of the twenty-first century, spreading within weeks from southern China to over thirty-seven countries around the world. In Canada intense news media coverage had a profound impact on how the disease was perceived, with frontline health care workers, despite their heroic efforts, stigmatized due to their contact with patients. Will SARS or another pandemic influenza reoccur and, if it does, have we learned how to manage pandemics more effectively? In SARS Unmasked risk communication expert Michael Tyshenko offers answers to this and other questions. Cathy Peterson, who worked as a nurse clinician during the Toronto SARS crisis, adds an important view from the frontlines. Their analysis reveals an out-of-control situation with mixed risk communication messages, a lack of leadership, and an overwhelmed health care system that was unable to both cope with the crisis in Toronto and provide adequate support for their most valuable employees at the time - health care workers. Taking a very broad perspective, grounded in risk assessment, SARS Unmasked adds important information to what has already been said about the 2003 crisis, focusing on the human and societal effects of an infectious disease pandemic and providing tangible guidance for future pandemic threats.




SARS-CoV-2 and Coronacrisis


Book Description

This book is useful for administrators of different levels involved in counteracting COVID-19, surveillance professionals, clinicians, researchers specializing in epidemiology, microbiology, and infectious diseases, and politicians / legislators engaged in public health sector. We use an innovative approach of combining both epidemiological and sociological analyses, as the very problem is mainly an issue of correct governance. A team of authors from Europe, Russia and China summarizes their experience and knowledge useful for containing SARS-CoV-2 and overcoming social and managerial consequences of the pandemic. The editors are sure that sharing our different experience would help to elaborate necessary strategies, protocols, and principles that may be effectively applied in the future to avoid dramatic consequences of not only COVID-19 but also any possible epidemiological hazards for people and medicine.







Textbook of SARS-CoV-2 and COVID-19 - E-Book


Book Description

Written by physicians and scientists with expertise in this evolving area, Textbook of SARS-CoV-2 and COVID-19 provides a coherent, readable, and clinically relevant review of the biology, epidemiology, pathophysiology, immunology, clinical features, current treatment, and prevention strategies for the SARS-CoV-2 virus. Using both a systemic and topic-based approach, it summarizes and clarifies the extensive literature published on SARS-CoV-2 and COVID-19, includes a comprehensive bibliography, and provides answers to clinical questions at the point of care from multiple specialty perspectives. - Includes dedicated chapters for pulmonary, cardiac, neurological, and oral manifestations of COVID-19. - Covers therapeutics and novel therapeutic targets of SARS-CoV-2 and COVID-19. - Addresses the diagnostic and management challenges of COVID-19 in the emergency department. - Discusses COVID-19 in special populations, including the effect of SARS-CoV-2 infection in pregnant mothers and to the fetus and newborn. - Provides a systematic overview and comparison of vaccines that are approved and in development.




COVID-19 SARS-COV-2 Prevention – Treatment - Cure


Book Description

The purpose of this book is to extrapolate and bridge the sciences of pulmonary diseases with sciences that help medical professionals solve challenges of epidemics and pandemics such as COVID-19 and SARS-COV-2. You will find in the text information that will give credence to achieve goals and therapies paralleling the highest levels of medical practice. Acute and chronic respiratory illnesses have now become acceptable as the most prominent of diseases in the world, and henceforth as predicted, the trifecta of illnesses that are inherently increasing rapidly. However, on another cascade of health conditions, there have been major advances in our understanding of respiratory diseases and significant improvement in their management, particularly with the early and more widespread use of PPE (Personal Protective Equipment)[ Leading Health Research Institute] and respiratory ventilators. Yet, despite effective therapy for respiratory diseases, there is a pressing need for new and more specific therapies that control respiratory diseases or even cure the underlying disease process.




Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection


Book Description

Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics compiles information about various computational bioinformatic approaches that can help combat viral infection. The book includes working knowledge of various molecular docking and molecular dynamic simulation approaches that have been exploited for drug repurposing and drug designing purpose. In addition, it sheds light on reverse vaccinomics and immunoinformatic approaches for vaccine designing against SARS-CoV2 infection. This book is an essential resource for researchers, bioinformaticians, computational biologists, computational chemists and pharmaceutical companies who are working on the development of effective and specific therapeutic interventions and point-of-care diagnostic devices using various computational approaches. - Covers computational based approaches for designing and repurposing drugs - Discusses immunoinformatic and reverse vaccinomic approaches for effective vaccine design - Categorizes information about artificial intelligence-based drug screening and diagnostic tools