Regulatory Toxicology in the European Union


Book Description

Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a concomitant need to understand the toxicological principles underlying safety assessments Regulatory Toxicology in the European Union is the first book to cover regulatory toxicology specifically in Europe. It addresses the need for a wider understanding of the principles of regulatory toxicology and their application and presents the relationship between toxicology and legislative processes in regulating chemical commodities across Europe. This title has a broad scope, covering historical and current chemical regulation in Europe, the role of European agencies and institutions, and also the use of toxicology data for important classes of chemicals, including human and veterinary medicines, animal feed and food additives, biocides, pesticides and nanomaterials. This book is therefore extremely pertinent and timely in the toxicology field at present. This book is an essential reference for regulatory authorities, industrialists, academics, undergraduates and postgraduates working within safety and hazards, toxicology, the biological sciences, and the medicinal and pharmaceutical sciences across the European Union.




Microbicides for the Protection of Materials


Book Description

This book is chiefly intended for those who are using microbicides for the protection of materials. Another purpose is to inform teachers and students working on biodeterioration and to show today's technical standard to those engaged in R&D activities in the microbicide field. When trying to classify, or to subclassify, material-protecting microbicides according to their mode of action, e.g. as membrane-active and electrophilic active ingredients, it turned out that a clear assignment was not always possible. For that reason the author has resorted to chemistry's principle of classifying according to groups of substances (e.g. alcohols, aldehydes, ketones, acids, esters, amides, etc.), thus providing the first necessary information about the micro bicides' properties. The description of the various groups of substances includes, whenever possible, an outline of the mode and mechanism of action of the active ingredients involved. The effective use of microbicides presupposes knowledge of their character istics. That is why the microbicides' chemico-physical properties, their toxicity, ecotoxicity, effectiveness, and effective spectrum are described in greater detail. As mentioned before, the characteristics of microbicides play an important role. They have to be suited to the intended application to avoid detrimental effects on the properties and the quality of the material to be protected; also production processes in which microbicides are used to avoid disturbances by microbial action must not be disturbed by the presence of those microbicides.




Advances in Marine Antifouling Coatings and Technologies


Book Description

Marine biofouling can be defined as the undesirable accumulation of microorganisms, algae and animals on structures submerged in seawater. From the dawn of navigation, marine biofouling has been a major problem for shipping in such areas as reduced speed, higher fuel consumption and increased corrosion. It also affects industries using off-shore structures such as oil and gas production and aquaculture. Growing concerns about the environmental impact of antifouling coatings has led to major new research to develop more environmentally-friendly alternatives. Advances in marine antifouling coatings and technologies summaries this wealth of research and its practical implications.This book is divided into four sub-sections which discuss: marine fouling organisms and their impact, testing and development of antifouling coatings, developments in chemically-active marine antifouling technologies, and new surface approaches to the control of marine biofouling. It provides an authoritative overview of the recent advances in understanding the biology of fouling organisms, the latest developments on antifouling screening techniques both in the field and in the laboratory, research on safer active compounds and the progress on nontoxic coatings with tailor-made surface properties.With its distinguished editors and international team of contributors, Advances in marine antifouling coatings and technologies is a standard reference for manufacturers of marine antifouling solutions, the shipping industry, oil and gas producers, aquaculture and other industries using offshore structures, and academics researching this important area. - Assesses marine antifouling organisms and their impact, including a historical review and directions for future research - Discusses developments in antifouling coatings examining chemically-active and new surface approaches - Reviews the environmentally friendly alternative of safer active compounds and the progress of non-toxic compounds




Caring for People who Sniff Petrol Or Other Volatile Substances


Book Description

These guidelines provide recommendations that outline the critical aspects of infection prevention and control. The recommendations were developed using the best available evidence and consensus methods by the Infection Control Steering Committee. They have been prioritised as key areas to prevent and control infection in a healthcare facility. It is recognised that the level of risk may differ according to the different types of facility and therefore some recommendations should be justified by risk assessment. When implementing these recommendations all healthcare facilities need to consider the risk of transmission of infection and implement according to their specific setting and circumstances.




Textiles, Denmark


Book Description




Additives for Coatings


Book Description

No doubt: A perfect coating has to look brilliant! But other properties of coatings are also most important. Coatings have to be durable, tough and easily applicable. Additives are the key to success in achieving these characteristics, even though the amounts used in coating formulations are small. It is not trivial at all to select the best additives. In practice, many series of tests are often necessary, and the results do not explain, why a certain additive improves the quality of a coating and another one impairs the coating. This book is dedicated to developers and applicants of coatings working in research or production, and it is aimed at providing a manual for their daily work. It will answer the following questions: How do the most important groups of additives act? Which effects can be be achieved by their addition? Scientific theories are linked to practical applications. Emphasis is put on the optical aspects that are most important for the applications in practice. This book is a milestone in quality assurance in the complete field of coatings!




Handbook of Material Biodegradation, Biodeterioration, and Biostablization


Book Description

Handbook of Material Biodegradation, Biodeterioration, and Biostabilization, Second Edition gives extensive information on the microorganisms involved in the biodegradation of materials, along with the biocides which are permitted for use according to the most up-to-date worldwide legislation. Mechanisms of biodegradation and biodeterioration, results of biodeterioration, and methods of biostabilization are covered for a large number of products, making the title relevant for a range of industries and applications, including construction, coatings/paints, medical and pharmaceutical applications, and electronics. In addition, the health and safety aspects of biocide application are covered in detail, as well as the personal protection of practitioners who are required to use them. The contents and the most-up-to-date information make this book essential for almost all the fields of applied chemistry. - Enables practitioners to identify the organisms responsible for biodeterioration in materials, select suitable preventative measures, and safely deploy methods of biostabilization - Contains information on the biostabilization of various industrial products, including 24 groups of polymers - Includes critical (and current) health and safety, environmental, and regulatory guidelines and best practices, and their relationships to legislation, regulation, toxicity, micro-organisms, biocides, and polymers - Essential reading for scientists and practitioners as new regulations eliminate the use of previously used materials - Contains up-to-date information on legislation and regulations governing the use of biocides in the European Union, the United States, and worldwide




Advanced Healthcare Materials


Book Description

Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers




Guidelines for the Evaluation of Antifouling Paints


Book Description

This report is intended to provide detailed guidelines for the assessment of public health, workers' health and environmental safety of pesticides for the control of fouling organisms normally called antifoulants.