Book Description
Dr. Baer is the site PI for a clinical trial investigating treatments related to Sjogren’s Syndrome, in conjunction with Viela Bio. The other Topic Editors declare no competing interests with relation to the topic theme.
Author : Kristi A. Koelsch
Publisher : Frontiers Media SA
Page : 349 pages
File Size : 38,48 MB
Release : 2022-03-09
Category : Medical
ISBN : 2889744825
Dr. Baer is the site PI for a clinical trial investigating treatments related to Sjogren’s Syndrome, in conjunction with Viela Bio. The other Topic Editors declare no competing interests with relation to the topic theme.
Author : Alessia Alunno
Publisher : Academic Press
Page : 346 pages
File Size : 39,33 MB
Release : 2016-06-07
Category : Medical
ISBN : 012803632X
Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus. - Discusses heterogeneity of topics and audience, from basic immunology to clinical aspects and therapeutics - Provides novel lines of investigation and supports the management of patients requiring novel therapeutic approaches - Presents a deeper knowledge on SS clinical management as well as on immunological aspects possibly leading to new lines of investigation - Offers a bridge between the clinician and the scientist, and vice versa - Provides the reader with most recent and relevant updates due to the novelty of topics
Author : Kenneth Murphy
Publisher : Garland Science
Page : pages
File Size : 13,82 MB
Release : 2010-06-22
Category : Medical
ISBN : 9780815344575
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Robert I. Fox
Publisher : Springer Science & Business Media
Page : 499 pages
File Size : 34,48 MB
Release : 2011-09-15
Category : Medical
ISBN : 1603279571
The key knowledge assembled in this book comprises today’s most comprehensive resource on Sjögren’s syndrome. Sjögren’s patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others. This practical clinical resource begins with an overview of Sjögren’s myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria. The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics. The third section is devoted to clinical manifestations and therapeutic considerations. It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book’s contributors. With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets. Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren’s patients and physicians.
Author : Marinos C. Dalakas
Publisher : Butterworth-Heinemann
Page : 362 pages
File Size : 38,56 MB
Release : 2013-10-22
Category : Health & Fitness
ISBN : 1483163040
Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.
Author : R.C. Kennedy
Publisher : Elsevier
Page : 557 pages
File Size : 41,20 MB
Release : 1997-11-19
Category : Medical
ISBN : 0080534430
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Author : Firas H. Kobeissy
Publisher : CRC Press
Page : 718 pages
File Size : 16,39 MB
Release : 2015-02-25
Category : Medical
ISBN : 1466565993
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Author : Daniel J. Wallace MD
Publisher : Oxford University Press
Page : 412 pages
File Size : 24,67 MB
Release : 2011-10-03
Category : Medical
ISBN : 0199911797
Afflicting one in seventy Americans, Sjögren's syndrome is an autoimmune disease that commonly causes dryness of the eyes, mouth, and nose, and that can lead to complications including profound fatigue, depression, and lymphoma. While there is no cure for Sjögren's, much can be done to alleviate the suffering of patients. This extensively revised handbook offers everything you need to know to cope with this disease. The Sjögren's Book, Fourth Edition is a comprehensive and authoritative guide, produced by the Sjögren's Syndrome Foundation and its medical advisors and edited by physician Daniel J. Wallace, a leading authority on autoimmune disorders. This expanded edition provides readers with the best medical and practical information on this disorder, bringing together the current thinking about Sjögren's in an easily readable and understandable book, with an entirely new section on lifestyle issues aimed at improving the quality of life for Sjögren's sufferers. With more than thirty chapters written by leading experts, the handbook illuminates the major clinical aspects of the syndrome and is loaded with practical tips and advice. Indeed, it offers a wide-ranging look at the many faces of Sjögren's, covering diagnosis, the various organ systems that can be affected, the possible psychological problems, and the many treatment options, as well as a concluding chapter listing the web, print, and media resources available. It is a valuable aid that patients can use while discussing their illness with their physician and an excellent resource for family members. And because Sjögren's is greatly underdiagnosed, this handbook is a particularly valuable resource for healthcare professionals. Recognized as the bible for Sjögren's suffers, this reliable and informative guide is the first place for patients to look when they have questions about this little known but serious chronic disease.
Author : Andrzej Górski
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 27,83 MB
Release : 2001-09-30
Category : Medical
ISBN : 9781402000379
"A series of articles deals with several aspects of the subject, such as the generation, progression and regulation of the autoimmune phenomena. The roles of pathogens, apoptosis, cytokines, complement components, regulatory T cells, as well as the association between the immune and neurohormonal systems in major autoimmune disorders are described." "This is not a textbook, but it is highly recommended for clinicians and university workers, and as a supplementary reading for lecturers and students."--Jacket.
Author : Yehuda Shoenfeld
Publisher : Elsevier Science Limited
Page : 523 pages
File Size : 44,24 MB
Release : 1989
Category : Medical
ISBN : 9780444811844
This book comprehensively sets out the common aetiopathogenetic mechanisms shared by many, apparently diverse, diseases of the immune system. Unlike most other texts it does not emphasise the differences between autoimmune diseases, but establishes their many common links including hormonal effects, dietary and immunogenetic influences, complement deficiencies and environmental factors. Special attention is given to the effects of ageing and the relationship with malignancies. The scope of the book is very broad so as to cover the integration of the many diverse components which interact to cause autoimmunity, and it contains many 1988 and 1989 references and over 100 figures and tables, offering an attractive, up-to-date guide to modern concepts. It will greatly assist immunologists wishing to enter the field of autoimmunity, and will serve as an invaluable reference work for those already working in it.