Steroids Made it Possible


Book Description

Carl Djerassi, primarily known as the inventor of the birth control pill, also developed many spectroscopic techniques for structure identification, including the earliest applications of mass spectroscopy of ORD/CD to organic chemical structure. His forceful manner and inquisitive mind are reflected in his prose to make this an enjoyable and educational work.




Game of Shadows


Book Description

In the summer of 1998 two of baseball leading sluggers, Mark McGwire and Sammy Sosa, embarked on a race to break Babe Ruth’s single season home run record. The nation was transfixed as Sosa went on to hit 66 home runs, and McGwire 70. Three years later, San Francisco Giants All-Star Barry Bonds surpassed McGwire by 3 home runs in the midst of what was perhaps the greatest offensive display in baseball history. Over the next three seasons, as Bonds regularly launched mammoth shots into the San Francisco Bay, baseball players across the country were hitting home runs at unprecedented rates. For years there had been rumors that perhaps some of these players owed their success to steroids. But crowd pleasing homers were big business, and sportswriters, fans, and officials alike simply turned a blind eye. Then, in December of 2004, after more than a year of investigation, San Francisco Chronicle reporters Mark Fainaru-Wada and Lance Williams broke the story that in a federal investigation of a nutritional supplement company called BALCO, Yankees slugger Jason Giambi had admitted taking steroids. Barry Bonds was also implicated. Immediately the issue of steroids became front page news. The revelations led to Congressional hearings on baseball’s drug problems and continued to drive the effort to purge the U.S. Olympic movement of drug cheats. Now Fainaru-Wada and Williams expose for the first time the secrets of the BALCO investigation that has turned the sports world upside down. Game of Shadows: Barry Bonds, BALCO, and the Steroid Scandal That Rocked Professional by award-winning investigative journalists Mark Fainaru-Wada and Lance Williams, is a riveting narrative about the biggest doping scandal in the history of sports, and how baseball’s home run king, Barry Bonds of the San Francisco Giants, came to use steroids. Drawing on more than two years of reporting, including interviews with hundreds of people, and exclusive access to secret grand jury testimony, confidential documents, audio recordings, and more, the authors provide, for the first time, a definitive account of the shocking steroids scandal that made headlines across the country. The book traces the career of Victor Conte, founder of the BALCO laboratory, an egomaniacal former rock musician and self-proclaimed nutritionist, who set out to corrupt sports by providing athletes with “designer” steroids that would be undetectable on “state-of-the-art” doping tests. Conte gave the undetectable drugs to 28 of the world’s greatest athletes—Olympians, NFL players and baseball stars, Bonds chief among them. A separate narrative thread details the steroids use of Bonds, an immensely talented, moody player who turned to performance-enhancing drugs after Mark McGwire of the St. Louis Cardinals set a new home run record in 1998. Through his personal trainer, Bonds gained access to BALCO drugs. All of the great athletes who visited BALCO benefited tremendously—Bonds broke McGwire’s record—but many had their careers disrupted after federal investigators raided BALCO and indicted Conte. The authors trace the course of the probe, and the baffling decision of federal prosecutors to protect the elite athletes who were involved. Highlights of Game of Shadows include: Barry Bonds A look at how Bonds was driven to use performance-enhancing drugs in part by jealousy over Mark McGwire’s record-breaking 1998 season. It was shortly thereafter that Bonds—who had never used anything more performance enhancing than a protein shake from the health food store—first began using steroids. How Bonds’s weight trainer, steroid dealer Greg Anderson, arranged to meet Victor Conte before the 2001 baseball season with...




Medicinal Chemistry of Steroids


Book Description

The many new and fascinating data which have been gathered in the period 1985-1990 have made molecular endocrinology into a mature discipline stimulating creative chemists to design innovative drugs. Within a few years, the primary structures of all the steroid receptor proteins and most of the steroid-converting enzymes have been determined and detailed studies of their mechanism of action at a molecular level have become possible. Medicinal chemists have developed steroidal affinity probes to examine the binding sites of enzymes and receptors, and these investigations were supplemented with studies of modified enzymes and receptors prepared with the aid of site-directed mutagenesis. In view of these rapid scientific developments, the author deemed it appropriate to review the present knowledge of the medicinal chemistry of the steroids. In this book, the discussion is supported by the addition of some chapters which summarize the available data on the biological counterparts of the steroids, the steroid-converting enzymes and the steroid receptors.




Basic Principles of Organic Chemistry


Book Description

Introduction what is organic chemistry all about?; Structural organic chemistry the shapes of molecules functional groups; Organic nomenclature; Alkanes; Stereoisomerism of organic molecules; Bonding in organic molecules atomic-orbital models; More on nomenclature compounds other than hydrocarbons; Nucleophilic substitution and elimination reactions; Separation and purification identification of organic compounds by spectroscopic techniques; Alkenes and alkynes. Ionic and radical addition reactions; Alkenes and alkynes; Oxidation and reduction reactions; Acidity or alkynes.




Better than steroids


Book Description

Better Than Steroids! is the secret to a bodybuilder's physique! Loaded with the exceptionally confidential information of successful bodybuilding, this book is a MUST for anyone wanting to look good!




Doping, Performance-Enhancing Drugs, and Hormones in Sport


Book Description

Doping, Performance-Enhancing Drugs, and Hormones in Sport: Mechanisms of Action and Methods of Detection examines the biochemistry and bioanalytical aspects of performance-enhancing drugs (PEDs) and other questionable procedures used by athletes to enhance performance. The book informs the specialist of emerging knowledge and techniques and allows the non-specialist to grasp the underlying science and current practice of the discipline. With clear and compelling language appropriate for a broad spectrum of readers, this book provides background on prevalence, types of agents, their actual or supposed benefits, and their negative effects on health. The technical aspects of detection are discussed, followed by a discussion of why detection is a problematic and still-evolving science. To facilitate comprehension, each chapter is organized in a uniform way with six sections: (1) standard medical uses, (2) why the drugs are used by athletes, (3) biological mechanism of action, (4) what research says about efficacy in improving performance, (5) major health side effects from use and abuse in sport, and 6) concluding key points. - Presents the scientific concepts of how performance enhancers work, how they are used, and how they are detected and masked from detection - Features language that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience - Provides a short "close-up in each chapter to illustrate key topics that engage, entertain, and create a novel synthesis of thought




The Steroids Game


Book Description

Discusses the effects of steroids on the body and on athletic performance, ways to prevent steroid use, treatment procedures, other ways to achieve the same results, and related matters.




Testosterone


Book Description

Testosterone lies at the heart of maleness, and is involved in aggression, competitiveness, and risk-taking -- all essential in our evolution. Joe Herbert describes the fascinating insights revealed by modern research into this primeval power that shaped our history and lurks below the veneer of our civilized modern world.




Legal Muscle


Book Description

This book shatters the myths and misconceptions about steroid use in America. Authored by the nationally recognized legal authority on anabolics and founder of www.SteroidLaw.com, it's essential reading for natural and juiced athletes alike, and for coaches, sports trainers, physicians, journalists, and anyone in the criminal justice system. Legal Muscle is the never-before-told truth!




Juiced


Book Description

When Jose Canseco burst into the Major Leagues in the 1980s, he changed the sport -- in more ways than one. No player before him possessed his mixture of speed and power, which allowed him to become the first man in history to belt more than forty home runs and swipe more than forty bases in the same season. He won Rookie of the Year, Most Valuable Player, and a World Series ring. Canseco shattered the mold of the out-of-shape baseball player and ushered in a new era of superathletes who looked like bodybuilders, made outrageous salaries, and enjoyed rock-star lifestyles. And the ticket for this ride? Steroids. Behind the gaudy stats and the glamour of his public life, Canseco cultivated a secret just about everyone in MLB knew about, one that would alter the game of baseball and the way we view our heroes forever. Canseco made himself a guinea pig of the performance-enhancing drugs that were only just beginning to infiltrate the American underground. Anabolic steroids, human growth hormones -- Canseco mixed, matched, and experimented to such a degree that he became known throughout the league as "The Chemist." He passed his knowledge on to trainers and fellow players, and before long, performance-enhancing drugs were running rampant throughout Major League Baseball. Sluggers scooping up pitches at their ankles and blasting them out of the park, pitchers cranking fastballs inning after inning -- Canseco showed the players how to customize their doses to sculpt the bodies they wanted, and baseball as we know it was the result. Today, this issue has crept out of the closet and burst into the headlines as players balloon to herculean proportions and hundred-year-old records are not only broken, but also demolished. In this shocking memoir, Canseco sheds light on a life of dizzying highs and debilitating lows, provides the answers to questions about steroids that millions of fans are only now beginning to ask -- and suggests that, far from being a passing trend, the steroid revolution is only a taste of things to come. Who's juiced? According to Canseco's authoritative account, more than you think. And baseball will never be the same.