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Book Description




Consilience


Book Description

NATIONAL BESTSELLER • "A dazzling journey across the sciences and humanities in search of deep laws to unite them." —The Wall Street Journal One of our greatest scientists—and the winner of two Pulitzer Prizes for On Human Nature and The Ants—gives us a work of visionary importance that may be the crowning achievement of his career. In Consilience (a word that originally meant "jumping together"), Edward O. Wilson renews the Enlightenment's search for a unified theory of knowledge in disciplines that range from physics to biology, the social sciences and the humanities. Using the natural sciences as his model, Wilson forges dramatic links between fields. He explores the chemistry of the mind and the genetic bases of culture. He postulates the biological principles underlying works of art from cave-drawings to Lolita. Presenting the latest findings in prose of wonderful clarity and oratorical eloquence, and synthesizing it into a dazzling whole, Consilience is science in the path-clearing traditions of Newton, Einstein, and Richard Feynman.




Fundamental Neuroscience


Book Description

Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness Additional text boxes describing key experiments, disorders, methods, and concepts Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing







Quantum Aspects of Life


Book Description

A quantum origin of life? -- Quantum mechanics and emergence -- Quantum coherence and the search for the first replicator -- Ultrafast quantum dynamics in photosynthesis -- Modelling quantum decoherence in biomolecules -- Molecular evolution -- Memory depends on the cytoskeleton, but is it quantum? -- Quantum metabolism and allometric scaling relations in biology -- Spectroscopy of the genetic code -- Towards understanding the origin of genetic languages -- Can arbitrary quantum systems undergo self-replication? -- A semi-quantum version of the game of life -- Evolutionary stability in quantum games -- Quantum transmemetic intelligence -- Dreams versus reality : plenary debate session on quantum computing -- Plenary debate: quantum effects in biology : trivial or not? -- Nontrivial quantum effects in biology : a skeptical physicists' view -- That's life! : the geometry of p electron clouds.




Generalized Linear Models With Examples in R


Book Description

This textbook presents an introduction to generalized linear models, complete with real-world data sets and practice problems, making it applicable for both beginning and advanced students of applied statistics. Generalized linear models (GLMs) are powerful tools in applied statistics that extend the ideas of multiple linear regression and analysis of variance to include response variables that are not normally distributed. As such, GLMs can model a wide variety of data types including counts, proportions, and binary outcomes or positive quantities. The book is designed with the student in mind, making it suitable for self-study or a structured course. Beginning with an introduction to linear regression, the book also devotes time to advanced topics not typically included in introductory textbooks. It features chapter introductions and summaries, clear examples, and many practice problems, all carefully designed to balance theory and practice. The text also provides a working knowledge of applied statistical practice through the extensive use of R, which is integrated into the text. Other features include: • Advanced topics such as power variance functions, saddlepoint approximations, likelihood score tests, modified profile likelihood, small-dispersion asymptotics, and randomized quantile residuals • Nearly 100 data sets in the companion R package GLMsData • Examples that are cross-referenced to the companion data set, allowing readers to load the data and follow the analysis in their own R session




Modeling Ordered Choices


Book Description

It is increasingly common for analysts to seek out the opinions of individuals and organizations using attitudinal scales such as degree of satisfaction or importance attached to an issue. Examples include levels of obesity, seriousness of a health condition, attitudes towards service levels, opinions on products, voting intentions, and the degree of clarity of contracts. Ordered choice models provide a relevant methodology for capturing the sources of influence that explain the choice made amongst a set of ordered alternatives. The methods have evolved to a level of sophistication that can allow for heterogeneity in the threshold parameters, in the explanatory variables (through random parameters), and in the decomposition of the residual variance. This book brings together contributions in ordered choice modeling from a number of disciplines, synthesizing developments over the last fifty years, and suggests useful extensions to account for the wide range of sources of influence on choice.




Mathematical Modeling in Experimental Nutrition


Book Description

Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understanding of nutrient action, nutritionists are increasingly turning their focus to the mathematical modeling of nutrient kinetic data. The availability of suitably-tagged (isotope) nutrients (such as B-carotene, vitamin A, folate, among others), sensitive analytical methods to trace them in humans (mass spectrometry and accelerator mass spectrometry), and powerful software (capable of solving and manipulating differential equations efficiently and accurately), has allowed researchers to construct mathematical models aimed at characterizing the dynamic and kinetic behavior of key nutrients in vivo in humans at an unparalleled level of detail.




The Cybernetics Moment


Book Description

Choice Outstanding Academic Title Cybernetics—the science of communication and control as it applies to machines and to humans—originates from efforts during World War II to build automatic antiaircraft systems. Following the war, this science extended beyond military needs to examine all systems that rely on information and feedback, from the level of the cell to that of society. In The Cybernetics Moment, Ronald R. Kline, a senior historian of technology, examines the intellectual and cultural history of cybernetics and information theory, whose language of “information,” “feedback,” and “control” transformed the idiom of the sciences, hastened the development of information technologies, and laid the conceptual foundation for what we now call the Information Age. Kline argues that, for about twenty years after 1950, the growth of cybernetics and information theory and ever-more-powerful computers produced a utopian information narrative—an enthusiasm for information science that influenced natural scientists, social scientists, engineers, humanists, policymakers, public intellectuals, and journalists, all of whom struggled to come to grips with new relationships between humans and intelligent machines. Kline traces the relationship between the invention of computers and communication systems and the rise, decline, and transformation of cybernetics by analyzing the lives and work of such notables as Norbert Wiener, Claude Shannon, Warren McCulloch, Margaret Mead, Gregory Bateson, and Herbert Simon. Ultimately, he reveals the crucial role played by the cybernetics moment—when cybernetics and information theory were seen as universal sciences—in setting the stage for our current preoccupation with information technologies. "Nowhere in the burgeoning secondary literature on cybernetics in the last two decades is there a concise history of cybernetics, the science of communication and control that helped usher in the current information age in America. Nowhere, that is, until now . . . Readers have in The Cybernetics Moment the first authoritative history of American cybernetics."—Information & Culture "[A]n extremely interesting and stimulating history of the concepts of cybernetics . . . This is a book for everyone to read, relish, and think about."—Choice "As a whole, the book presents a comprehensive in-depth retrospective analysis of the contribution of the American scientific school to the making, formation, and development of cybernetics and information theory. An unquestionable advantage of the book is the skillful use of numerous bibliographic sources by the author that reflect the scientific, engineering, and social significance of the questions being considered, competition of ideas and developments, and also interrelations between scientists."—Cybernetics and System Analysis "Dr. Kline is perhaps uniquely situated to take on so large and complicated [a] topic as cybernetics . . . Readers unfamiliar with Wiener and his work are well advised to start with this well-written and thorough book. Those who are already familiar will still find much that is new and informative in the thorough research and reasoned interpretations."—IEEE History Center "The most comprehensive intellectual history of cybernetics in Cold War America."—Journal of American History "The book will be most valuable as historical background for the large number of disciplines that were involved in the cybernetics moment: computer science, communications engineering, information theory, and the social sciences of sociology and anthropology."—IEEE Technology and Society Magazine "Ronald Kline’s chronicle of cybernetics certainly does what an excellent history of science should do. It takes you there—to the golden age of a new, exciting field. You will almost smell that cigar."—Second-Order Cybernetics "Kline’s The Cybernetics Moment tracks the rise and fall of the cybernetics movement in more detail than any historical account to date."—Los Angeles Review of Books