Saving Lives, Buying Time


Book Description

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.




Silent Spring


Book Description

The essential, cornerstone book of modern environmentalism is now offered in a handsome 40th anniversary edition which features a new Introduction by activist Terry Tempest Williams and a new Afterword by Carson biographer Linda Lear.




The Excellent Powder


Book Description

It's the world's most successful public health insecticide, saving millions upon millions of lives from preventable, insect-borne diseases. Yet despite decades of use and thousands of studies on its effects, DDT remains the world's most misunderstood chemical. Orchestrated, well-financed, earnest, but myth-based campaigns forced most countries to ban DDT without scientific justifica­tion. These campaigns created a climate of irrational fear and ignorant prejudice around DDT and have condemned millions of the world's most vulnerable people to death. The Excellent Powder dispels these myths and sets the record straight. It reviews the fascinating history of this chemical that changed the world. It analyzes the scientific evidence and explains how and why DDT safely protects millions from the threat of malaria and other diseases. Finally, it documents how many activists choose to ignore this evidence, and how their ignorant prejudices continues to under­mine disease control programs. "DDT has been the main agent in eradicating malaria ... and of having saved at least 2 billion people in the world without causing the loss of a single life by poisoning from DDT alone." World Health Organization, 1969 "The ban on DDT, founded on erroneous or fraudulent reports . . . has caused millions of deaths ..." 7 Gordon Edwards, scientist & entomologist, 2004




DDT


Book Description







DDT and the American Century


Book Description

Praised for its ability to kill insects effectively and cheaply and reviled as an ecological hazard, DDT continues to engender passion across the political spectrum as one of the world's most controversial chemical pesticides. In DDT and the American Century, David Kinkela chronicles the use of DDT around the world from 1941 to the present with a particular focus on the United States, which has played a critical role in encouraging the global use of the pesticide. Kinkela's study offers a unique approach to understanding both this contentious chemical and modern environmentalism in an international context.




Malaria Control During Mass Population Movements and Natural Disasters


Book Description

Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migration at the Mailman School of Public Health of Columbia University have commissioned a series of epidemiological reviews on priority public health problems for forced migrants that will update the state of knowledge. Malaria Control During Mass Population Movements and Natural Disasters- the first in the series, provides a basic overview of the state of knowledge of epidemiology of malaria and public health interventions and practices for controlling the disease in situations involving forced migration and conflict.




Insecticides Resistance


Book Description

This book contains 20 chapters, which are divided into 5 sections. Section 1 covers different aspects of insecticide resistance of selected economically important plant insect pests, whereas section 2 includes chapters about the importance, development and insecticide resistance management in controlling malaria vectors. Section 3 is dedicated to some general questions in insecticide resistance, while the main topic of section 4 is biochemical approaches of insecticide resistance mechanisms. Section 5 covers ecologically acceptable approaches for overcoming insecticide resistance, such are the use of mycoinsecticides, and understanding the role of some plant chemical compounds, which are important in interactions between plants, their pests and biological control agents.




Voltage Gated Sodium Channels


Book Description

A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.




Disease Control Priorities, Third Edition (Volume 6)


Book Description

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.




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