Author : Tomasz Puzyn
Publisher : Royal Society of Chemistry
Page : 379 pages
File Size : 48,66 MB
Release : 2012
Category : Science
ISBN : 1849734534
This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques.
Author : Ramazan Asmatulu
Publisher : Newnes
Page : 257 pages
File Size : 46,19 MB
Release : 2013-06-12
Category : Technology & Engineering
ISBN : 0444594582
Nanotechnology is a new and emerging discipline that is multidisciplinary and interdisciplinary. The usage of nanosystems, nanomaterials, nano-devices, etc. permeates all aspects of society. Cancer targeting and curing nanosystems are being introduced into the biomedical and pharmaceutical industries; so are lightweight energy absorbing or blast-proof nanohybrid material in the aerospace, automotive and marine industries and high-efficiency energy harvesting nanomaterials, etc. Society has a vested interest in knowing how these new materials, devices and systems are changing the economy and similar landscapes. The book outlines the regulatory and environmental issues related to nanotechnology per industry, offers guidelines in assessing the risks and discusses the legal and socioeconomical issues involved. Case studies will be utilized to provide examples of the positive and negative impacts of nanotechnology. - Provides an overview and the basis for understanding the critical importance of the reactivity and efficacy of nanomaterials and the emerging role of nanotechnology in society - Explains the fundamentals, ethics, regulatory and environmental issues of nanosafety and how they shape the emerging nanotechnology industry and markets and includes extensive lists of glossary terms, terminologies and concepts needed for Material Data Safety Sheets - Discusses the relevance and specificity of nanosafety issues per industry and includes discussions on the "Homeland Security and Infrastructure Industries" of interest to society in general - Includes nanotechnology risk assessment and delineates and quantifies the risk assessment process for nanotechnology safety of paramount importance to most industries and systems - Outlines the legal and intellectual property ramifications of nanotechnology and its impact on productivity and society
Author : Nancy A. Monteiro-Riviere
Publisher : CRC Press
Page : 516 pages
File Size : 29,68 MB
Release : 2014-03-03
Category : Medical
ISBN : 1482203871
Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.
Author : Alok Dhawan
Publisher : Royal Society of Chemistry
Page : 380 pages
File Size : 27,16 MB
Release : 2017-11-13
Category : Medical
ISBN : 178262158X
This book fills the significant nanotoxicology and nanosafety knowledge gaps and covers a broad range of topics. It targets postgraduates, academics, and practicing industrialists.
Author : Agnieszka Gajewicz
Publisher : CRC Press
Page : 570 pages
File Size : 33,64 MB
Release : 2019-11-13
Category : Medical
ISBN : 1000680886
The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials (ENMs) has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of ENMs, computational methods originally developed for regular chemicals cannot always be applied explicitly in nanotoxicology. This book discusses the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. It focuses on (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics), (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across), and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics). It reviews methods of calculating molecular descriptors sufficient to characterize the structure of nanoparticles, specifies recent trends in the validation of computational methods, and discusses ways to cope with the uncertainty of predictions. In addition, it highlights the status quo and further challenges in the application of computational methods in regulation (e.g., REACH, OECD) and in industry for product development and optimization and the future directions for increasing acceptance of computational modeling for nanotoxicology.
Author : Matthew Hull
Publisher : William Andrew
Page : 463 pages
File Size : 32,20 MB
Release : 2014-06-11
Category : Medical
ISBN : 1455731900
Nanotechnology Environmental Health and Safety, Second Edition focuses not only on the impact of nanotechnology and the discipline of nanotoxicity, but also explains each of these disciplines through in the context of management requirements and via risk scenarios — providing an overview of regulation, risk management, and exposure. Contributors thoroughly explain environmental health and safety (EHS) issues, financial implications, foreseeable risks (e.g., exposure, dose, hazards of nanomaterials), occupational hygiene, and consumer protection.Key new chapters have been included covering eco-toxicity, nanomedicine, informatics, and future threats. New case studies have also been added, including a chapter on the impact of nanosilver on the environment, as well as an assessment of how well lessons have been learned from the past, such as in the case of asbestos. The book also makes a business case for the importance of proactive EHS management - essential reading for existing or prospective producers of nanoscale products. - Practical guidance on risk management and mitigation across different legislative frameworks worldwide - Reviews toxicological studies and industrial initiatives, supported by numerous case studies - Includes extensive new material on the implications of nanotechnology for medicine, energy and food, as well as assessing future threats
Author : H. Baharvand
Publisher : John Wiley & Sons
Page : 438 pages
File Size : 39,58 MB
Release : 2015-03-30
Category : Science
ISBN : 1118540611
Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside. Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.
Author : Lang Tran
Publisher : Springer
Page : 360 pages
File Size : 44,7 MB
Release : 2017-02-06
Category : Medical
ISBN : 3319477544
In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.
Author : Omar Azzaroni
Publisher : Royal Society of Chemistry
Page : 534 pages
File Size : 15,65 MB
Release : 2022-02-09
Category : Science
ISBN : 1788019628
The concept of nanoarchitechtonics was introduced to describe the correct manipulation of nanoscale materials in the creation of nano-devices and applications. Nanoarchitectonics has begun to spread into many fields including nanostructured materials synthesis, supramolecular assembly, nanoscale structural fabrications, materials hybridizations, materials and structures for energy and environmental sciences, device and physical application, and bio- and medical applications. Following on from the 2012 title Manipulation of Nanoscale Materials, Concepts and Design of Materials Nanoarchitectonics covers the introductory features underlying the field, presenting a unifying overview of the theoretical aspects and emerging applications that are changing the capability to understand and design advanced functional materials. Edited by pioneers of the field, this book will appeal to researchers working in nanoscience, materials science, supramolecular chemistry, physical chemistry and organic chemistry, as well as graduate students in these areas.
Author : Sharda Sundaram Sanjay
Publisher : Springer Nature
Page : 118 pages
File Size : 49,34 MB
Release : 2021-08-27
Category : Science
ISBN : 9811611432
This book highlights the nano-antioxidants and their potential therapeutic applications. The chapters start with basic information on free radicals and antioxidants, through natural antioxidants, mechanisms of their action, ending with the use of nano-antioxidants particularly its potential therapeutic applications. Nano-antioxidant therapy has a promising future that has to be explored. It is a bridge topic to connect the already existing literature with potential therapeutic highlights. This book is designated for students and researchers interested in Biochemistry, Chemistry, Physics, Food Science and nutrition, Pharmaceutical Science and Medicine. It would also be interesting to global audiences from human and animal nutrition to food preservation and packaging.
