Ultrastructural Pathology of the Cell and Matrix, Vol 2 Fourth Edition


Book Description

Ghadially successfully collects, classifies, describes, and illustrates the ultrastructure of every normal and pathological intracellular and extracellular structure in humans and other animals.This authoritative work serves as a textbook and atlas of cellular pathology at the ultrastructural level. There is no other book from which one may learn in a systemic fashion about the numerous changes that occur in cellular organelles and inclusions as a result of disease or experimental procedures. The 4th edition includes a number of new ultrastructural changes and lesions such as, secretory granules in bronchio-alveolar carcinoma, fibrohistiocytes, crinophagy in normal and neoplastic cells, and interdigitations and infoldings of the cell membrane.




Ultrastructural Pathology of the Cell and Matrix, 4Ed


Book Description

Ghadially successfully collects, classifies, describes, and illustrates the ultrastructure of every normal and pathological intracellular and extracellular structure in humans and other animals. This authoritative work serves as a textbook and atlas of cellular pathology at the ultrastructural level. There is no other book from which one may learn in a systemic fashion about the numerous changes that occur in cellular organelles and inclusions as a result of disease or experimental procedures. The 4th edition includes a number of new ultrastructural changes and lesions such as, secretory granules in bronchio-alveolar carcinoma, fibrohistiocytes, crinophagy in normal and neoplastic cells, and interdigitations and infoldings of the cell membrane.




Ultrastructural Pathology of the Cell and Matrix


Book Description

Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume I present a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the physiological analysis of the nucleus; nuclear matrix, interchromatin, and perichromatin granules; structure and function of centrioles; characteristics of mitochondria; Golgi complex in cell differentiation and neoplasia; and degranulation of rough endoplasmic reticulum. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, scientists, students, and researchers.




Ultrastructural Pathology


Book Description

Explains and integrates all aspects of ultrastructural pathology in human and animal tissue occurring from natural and experimental disease.




Information Resources in Toxicology, Volume 1: Background, Resources, and Tools


Book Description

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals Explores recent internet trends, web-based databases, and software tools in a section on the online environment Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field




Bancroft's Theory and Practice of Histological Techniques E-Book


Book Description

For 40 years, Bancroft’s Theory and Practice of Histological Techniques has established itself as the standard reference for histotechnologists and laboratory scientists, as well as histopathologists. With coverage of the full range of histological techniques used in medical laboratories and pathology departments, it provides a strong foundation in all aspects of histological technology – from basic methods of section preparation and staining, to advanced diagnostic techniques such as immunocytochemistry and molecular testing. This revised and updated 8th Edition by Kim S. Suvarna, Christopher Layton, and John D. Bancroft is a one-stop reference for all those involved with histological preparations and applications, from student to highly advanced laboratory professional.




Toxicologic Pathology


Book Description

As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Safety Assessment presents a histopathologic description of lesions observed during drug development and discusses their implication in the drug development process. Divided into two sections, the book systematically assists pathologists in making a determination as to the origin and potential importance of a lesion and its relevance for assessing human risk. The first section includes eight "concept" chapters to orient pathologists in areas that are important for effective interaction with other pathologists as well as the many non-pathologists involved in drug development. The second section is made up of organ-based chapters, each including light microscopic and electron microscopic descriptions of pathological lesions, differential diagnoses, biological consequences, pathogenesis, mechanism of lesion formation, and the expected clinical pathology correlates. This volume presents critical information—both published and unpublished and gained through personal experience—to improve the quality of drug safety evaluation and to expedite and improve the efficiency of the process. This book is crafted to assist students, residents, and toxicologic pathologists in their early career phase by serving as a resource that can effectively be used as a ready reference next to the microscope. In addition, more experienced pathologists will find this volume to be invaluable during their assessments. The book is also a valuable reference for toxicologists to assist in understanding compound-related pathological findings and to provide background for working on a range of toxicological problems.




Information Resources in Toxicology


Book Description

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the “hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. International in scope, with contributions from over 30 countries Numerous key references and relevant Web links Concise narratives about toxicologic sub-disciplines Valuable appendices such as the IUPAC Glossary of Terms in Toxicology Authored by experts in their respective sub-disciplines within toxicology




Diagnostic Electron Microscopy of Tumours


Book Description

Diagnostic Electron Microscopy of Tumors, Second Edition is a guide on how to employ electron microscopy techniques in making evaluation on tumor biopsies. This edition aims to serve as a source of information, references, and electron micrographs for the practicing electron microscopists. This book is divided into five parts; each of which tackles a different topic. Part 1 discusses the collection of specimen, and Part 2 talks about the assessment of tumors' behavior and growth. Ultrastructural analysis of diagnostic problems is covered in Part 3; the significance of some ultrastructural features in tumors is explained in Parts 4 and 5. This text is recommended for those who wish to examine tumor biopsies with an electron microscope as well as those who want to become more conversant with such matters, so that they can understand and evaluate electron micrographs and reports. This book will be valuable to physicians, surgeons, histopathologists, and pathology residents.