Author : Nan-Shan Chang
Publisher : Frontiers Media SA
Page : 138 pages
File Size : 49,18 MB
Release : 2019-11-18
Category :
ISBN : 288963177X
Author : David A. Frank
Publisher : Springer Science & Business Media
Page : 358 pages
File Size : 29,55 MB
Release : 2002-12-31
Category : Medical
ISBN : 1402073402
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Author : Anne Le
Publisher : Springer
Page : 186 pages
File Size : 15,42 MB
Release : 2018-06-26
Category : Medical
ISBN : 331977736X
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author : Krishna C. Persaud
Publisher : CRC Press
Page : 237 pages
File Size : 21,12 MB
Release : 2016-04-19
Category : Medical
ISBN : 1439871728
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Author : Jahangir Moini
Publisher : Academic Press
Page : 554 pages
File Size : 48,76 MB
Release : 2021-04-09
Category : Medical
ISBN : 0128217553
Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. - Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others - Includes full color figures, photos, tables, graphs and radioimaging - Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors - Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment
Author : Kiyoko F. Aoki-Kinoshita
Publisher : CRC Press
Page : 264 pages
File Size : 46,3 MB
Release : 2009-11-19
Category : Science
ISBN : 1000687538
A Focused, State-of-the-Art Overview of This Evolving FieldPresents Various Techniques for GlycoinformaticsThe development and use of informatics tools and databases for glycobiology and glycomics research have increased considerably in recent years. In addition to accumulating well-structured glyco-related data, researchers have now developed semi
Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
Page : 728 pages
File Size : 31,64 MB
Release : 2010
Category : Government publications
ISBN :
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : Rosanna Parlato
Publisher : Frontiers Media SA
Page : 102 pages
File Size : 44,95 MB
Release : 2020-05-21
Category :
ISBN : 2889637115
Author :
Publisher :
Page : 0 pages
File Size : 41,25 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : Ian Macreadie
Publisher : MDPI
Page : 228 pages
File Size : 29,52 MB
Release : 2019-10-25
Category : Science
ISBN : 3039214071
Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue.
