Insecticides with Novel Modes of Action


Book Description

The future of insect control looked very bright in the 1950s and 1960s with new insecticides constantly coming onto the market. Today, however, whole classes of pesticide chemistry have fallen by the wayside due to misuse which generated resistance problems reaching crisis proportions, severe adverse effects on the environment, and public outcry that has led to increasingly stricter regulation and legislation. It is with this background, demanding the need for safer, environmentally friendly pesticides and new strategies to reduce resistance problems, that this book was written. The authors of the various chapters have a wealth of experience in pesticide chemistry, biochemical modes of action, mechanism of resistance and application, and have presented concise reviews. Each is actively involved in thedevelopment of new groups of pesticide chemistry which led to the development of novel insecticides with special impact in controlling agricultural pests. Emphasis has been given to insecticides with selective properties, such as insect growth regulators hormone mimics, ecdysone agonists), (chitin synthesis inhibitors, juvenile chloronicotinyl insecticides (imidacloprid, acetamiprid), botanical insecticides (neem, plant oils), pymetrozine, diafenthiuron, pyrrole insecticides, and others. The importance of these compounds, as components in integrated pest management programs and in insecticide resistance management strategies, is discussed. The data presented are essential in establishing new technologies and developing novel groups of compounds which will have impact on our future agricultural practices.




Chitin and Benzoylphenyl Ureas


Book Description

The opportunity to explore a developing new technology in a single biological system, chitin, from the molecular basis and with the inter relationship of the utilization of benzoylphenyl ureas in effective pest agroecosystem management strategies, represents a new evolution for integration of knowledge in this highly complex area. The degree of great progress and interest in the understanding of the interaction of chitin uItrastructures, biochemistry, and the unique ben zoylphenyl ureas attest to the timeliness of this effort. The purpose of the book that follows is to provide up-to-date and well illustrated details of current research knowledge including the latest of research results. The combination of the basic to the applied aspects rarely occurs specifically at the levels presented by the international contributors within. The original contributions composed the symposium "Chitin and Ben zoylphenyl Urea" organized by the co-editors at the International Con gress of Entomology in Hamberg, Germany, August 1984. We extend our appreciation to everyone who made the conference an outstanding success and highlight of the Congress, as well as making this book possible. We thank the authors, especially for their excellent international presenta tions, discussions, and preparation of the manuscripts. The knowledge evolved from many areas in chitin research, as well as the intricate com plexity of successful utilization of specific knowledge involving benzoylp henyl ureas in system management strategies for insects will continue to be in the forefront throughout the world's agroecosystems; and hopefully this book will enhance further research and development.




Insect Hormones and Bioanalogues


Book Description

The application of organic insecticides in the agrotechnical praxis resulted in a great and unexpected progress in the control of insect pests, and was of a great economical value all over the world. The widespread application of these agents, however, is also accompanied by negative effects. The principal drawback of classical insecticides consists in the lack of their specificity, the useful insects being killed together with insect pests. Furthermore, the broad-scale application for many years led to the formation of more resistant insect strains requiring higher and higher doses of insecticides. The residues of the mostly used chlorinated compounds accumulate in human and animal foods producing directly or indirectly harmful effects in human sub jects. The critical situation led in many developed countries to the restriction in the usage of some types of classical insecticides. Under these circumstances it is quite natural that novel routes for the control of insect pests are investigated. In this connection, attention has been paid especially to the insect endocrinology and insect hormones which regulate the admirable and in many regards specific development from the egg to the adult insect. The recent successful discoveries in this field are thus in close relation to the practical requirements. Isolation and identification of moulting hor mones and juvenile-hormone-like naturally occurring substances not only made possible an exact investigation of their physiological effects but also stimulated the chemical research.




Progress in Ecdysone Research


Book Description




IRM Program


Book Description










Bacillus Thuringiensis, An Environmental Biopesticide


Book Description

The challenge of bacillus thuringiensis. Historiacal overview: from discovery until 1980s. The 1980s: a decade of change. The future challenge. Diversity of bacillus thuringiensis toxins and genes. Diversity of B. thuringiensis strains and toxins. Localization and molecular organization of the toxin genes. The crystal protein genes and products. Regulation of crystal synthesis. Domain-function studies of bacillus thuringiensis crystal proteins: a genetic approach. Mode of action structural features of crystal proteins. Crystal protein mutants. Crystal protein hybrids. Transgenic bacteria, viruses, algae and other microorganisms as bacillus thuringiensis toxin delivery systems. Conventional B. thuringiensis products: do they nedd to be improved?. The use of transgenic microorganisms to improve insect host range. Improving foliar acticity and delivery. Improving aquatic activity and delivery. Improving soil activity and delivery. Issues in the development of transgenic microorganisms. The engineering of plants to express bacillus thuringiensis -endotoxins. Expression of -endotoxins in dicotyledons. Expression of -endotoxins in monocotyledons. Quantification of -endotoxins expression in planta. Enhancement of -endotoxin expression in planta. Endophyte expression of -endotoxin genes in plants. Control of lepidopteran pests with bacillus thuringiensis. Conventional and genetically engineered b. thuringiensis. Products. Microbial specificity of b. thuringiensis in lepidopteran pests. Entomological aspects of lepidopteran pest control with B. thuringiensis. Integration of B. thuringiensis in lepidopteran pest control strategies. Use of bacillus thuringiensis israelensis against mosquitoes and blackflies. Properties of B. thuringiensis israelensis. Factors influencing the efficacy of B. thuringiensis israelensis treatments. Organization of mosquito control programmes. Successful control programmes using B. thuringiesis israelensis. Future prospects for the use of B. thuringiensis israelensis. Control of coleopteran pests by bacillus thuringiensis. B. thuringiensis tenebrionis products and their registration. Characterization of B. thuringiensis tenebrionis and other coleopteran-active subspecies. Host range of B. thuringiensis tenebrionis and susceptibility levels of some pest species. The impact of B. thuringiensis tenebrionis on nor-target animals. Control of coleoptera by -exotoxin. Field trials with B. thuringiensis tenebrionis. Future prospects. Bacillus thuringiensis in the environment: ecology and risk assessment. Role in the environment. Risk assessment. Resistance to bacillus thuringiensis and resistance management. Field resistance development to B. thuringiensis. Laboratory selection for resistance. Cross resistance of B. thuringiensis to chemicals and other B. thuringiensis strains. Genetics of resistance. Mechanisms of resistance. Strategies for delaying resistance development. The use of bacillus thuringiensis in developing countries. History and usage of B. thuringiensis in developing nations. Strain survey and selection. Production levels and costs. Inexpensive and local fermentation media. Low technology fermentation procedures. Stability and formulation. Field application. Further development of B. thuringiensis. Future role for B. thuringiensis in developing countries. Production of bacillus thuringiensis insecticides for experimental and commercial uses. Optimization of production methods. Production methods for B. thuringiensis. Quality control.