Mitochondrial Medicine


Book Description

Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.




Avalanche Dynamics


Book Description

Avalanches, mudflows and landslides are common and natural phenomena that occur in mountainous regions. With an emphasis on snow avalanches, this book provides a survey and discussion about the motion of avalanche-like flows from initiation to run out. An important aspect of this book is the formulation and investigation of a simple but appropriate continuum mechanical model for the realistic prediction of geophysical flows of granular material.




Environmental Geomechanics


Book Description

This book covers a range of topics that are of increasing importance in engineering practice: natural hazards, pollution, and environmental protection through good practice. The first half of the book deals with natural risk factors, of both natural and human origin, that should be considered: subsidence, accidental infiltration, soil instability, rockslides and mudslides, debris flow, and degradation of buildings and monuments due to pollution and climactic effects, for example. These problems are highlighted and it is shown that a combination of sophisticated numerical techniques and extensive experimental investigations are necessary in order to effectively tackle these problems. The second half of the book is devoted to the use of polluted sites and associated problems, a topic of growing significance given the increasing reclamation of land from abandoned industrial sites for urban development over the last 20 years. Different types of oil pollution and decontamination methods are described, followed by a discussion of waste management and detailed coverage of confinement liners used in surface waste disposal.




Landslide Science and Practice


Book Description

This book contains peer-reviewed papers from the Second World Landslide Forum, organised by the International Consortium on Landslides (ICL), that took place in September 2011. The entire material from the conference has been split into seven volumes, this one is the seventh: 1. Landslide Inventory and Susceptibility and Hazard Zoning, 2. Early Warning, Instrumentation and Monitoring, 3. Spatial Analysis and Modelling, 4. Global Environmental Change, 5. Complex Environment, 6. Risk Assessment, Management and Mitigation, 7. Social and Economic Impact and Policies.




Snow Engineering V


Book Description

Specialists in building and civil engineering, architecture, traffic and transport engineering, urban planning and avalanche science came together at the Fifth International Conference on Snow Engineering, organized by the Federal Swiss Institute for Snow and Avalanche Research in Davos 2004. This event belongs to a series of Snow Engineering Conferences held every four years since 1988. These conferences have become an important event for the international exchange of information on recent developments in snow engineering. The following thematic areas were discussed in the technical sessions and are here presented in this volume: - Transportation - Housing and Residential Planning - Snow Loads - Ski Mechanics - Hazard Mitigation - Snow Technology and Science - Avalanche Engineering







The Avalanche Handbook


Book Description

Technical yet accessible, The Avalanche Handbook, 3rd Edition, covers the formation, character, effects, and control of avalanches; rescue techniques; and research on understanding and surviving avalanches. Illustrated with nearly 200 updated illustrations, photos and examples, the revised edition offers exhaustive information on contributing weather and climate factors, snowpack analysis, the newest transceiver search techniques, and preventative and protective measures, including avalanche zoning and control. It contains new information on the unique characteristics of alpine snow, snow slab instability, terrain variables, skier triggering of avalanches, and the nature of avalanche motion. Plus brand-new chapters on the elements of backcountry avalanche forecasting and the decision-making process.




Theoretical and Applied Mechanics


Book Description

Theoretical and Applied Mechanics covers the proceedings of the 16th International Congress of Theoretical and Applied Mechanics, held at the Technical University of Denmark, Lyngby, Denmark on August 19-25, 1984. The contributors consider the significant advances in the thriving field of mechanics. This book is composed of 21 chapters, and begins with an overview of space research contributions in understanding fluid media mechanics. This topic is followed by discussions on some aspects and fundamentals of mechanics, such as chaos, computer application, resonant phenomena, adiabaticity, and nonlinear acoustics. The following chapters explore the various applications of theoretical and applied mechanics, including in marine structures, oil recovery, and ice and snow mechanics. This book also deals with nonlinear wave motion, hydrodynamic systems, ocean wave spectra, and Helmholtz concept. The remaining chapters look into the issues of steady water bifurcation, concept of anisotropic soils, and flow visualization. This book is of great value to physicists and research workers who wish to expand their knowledge in mechanics.