Author : Harinder Gill
Publisher : Frontiers Media SA
Page : 77 pages
File Size : 29,98 MB
Release : 2022-02-22
Category : Medical
ISBN : 2889744752
Author : Ajay Vora
Publisher : Springer
Page : 345 pages
File Size : 18,55 MB
Release : 2017-04-21
Category : Medical
ISBN : 3319397087
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author : Oussama Abla
Publisher : Springer
Page : 275 pages
File Size : 27,46 MB
Release : 2018-04-25
Category : Medical
ISBN : 331964257X
This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges. Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.
Author : Hillard M. Lazarus
Publisher : Springer Science & Business Media
Page : 885 pages
File Size : 22,72 MB
Release : 2010-03-02
Category : Medical
ISBN : 1597454788
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Author : Hagop M. Kantarjian
Publisher : McGraw-Hill Prof Med/Tech
Page : 1172 pages
File Size : 14,61 MB
Release : 2006-03-22
Category : Medical
ISBN : 9780071414999
A concise, up-to-date clinician's guide to cancer management -- from the leaders in the field A Doody's Core Title! The MD Anderson Cancer Center is ranked as the world's leading institution in cancer medicine. With publication of the MD Anderson Manual of Medical Oncology, the editorial board of this prestigious institution makes available for the first time a resource that meets the needs of clinicians for an authoritative, accessible guide to the medical management of patients with cancer and its complications. Straight-to-the-point, state-of-the-art strategies for cancer management Gives physicians a current, coherent approach to each disease and situation -- imbued with the clinical expertise and teaching authority of world class oncology researchers/practitioners Consistently formatted for a unified patient management strategy Packed with time-saving features, including “The M.D. Anderson Work-Up Box” and “The M.D. Anderson Preferred Treatment Box” Examines special issues in breast cancer management…current treatment strategies for infection in the neutropenic patient and management of fungal and viral infections in cancer patients… basic concepts and controversies related to allogeneic marrow transplantation…more Provides guidelines for oncologic emergencies and palliative care Outlines procedures for symptom control in long-term survival… long-term follow-up in pediatric and adult patients…and rehabilitation
Author :
Publisher :
Page : 0 pages
File Size : 20,56 MB
Release : 2025
Category :
ISBN : 9783031440823
Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
Page : 2004 pages
File Size : 21,53 MB
Release : 2017-03-10
Category : Medical
ISBN : 111900084X
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author : Ching-Hon Pui
Publisher : Cambridge University Press
Page : 893 pages
File Size : 12,78 MB
Release : 2012-06-21
Category : Medical
ISBN : 1139510223
New insights into the molecular biology of childhood leukemias have stimulated numerous advances in diagnostic methods, strategies for risk assessment and the development of novel therapy for genetic subtypes of the diseases. Fully revised and updated, this new edition of Childhood Leukemias provides the most comprehensive, clinically-oriented and authoritative reference dedicated to these diseases. Beginning with an overview of history, cell biology, and pathology, subsequent chapters review approaches in the evaluation and management of specific leukemias, new therapeutic development and the unique pharmacodynamics and pharmacogenetics of individual patients. New chapters include epigenetics of leukemias, leukemias in patients with Down syndrome and leukemia in adolescents and young adults. The final section covers the complications associated with the disease or its treatment and supportive care during and after treatment. Authored by leading experts, this is a 'must-have' for any physician or investigator who deals with leukemias in childhood.
Author : Bob Lowenberg
Publisher :
Page : pages
File Size : 27,18 MB
Release : 2014-01-01
Category :
ISBN : 9780982843536
This new compendium features 33 How I Treat articles published in Blood, which have been reviewed and updated to reflect the most recent scientific and clinically relevant information that has come to light since the articles were first published. The volume focuses on areas of hematology where there have been significant changes in our understanding of the biology of diseases and/or where clinical developments have significantly evolved.
Author : National Academies of Sciences Engineering and Medicine
Publisher :
Page : pages
File Size : 11,5 MB
Release : 2021-09-09
Category :
ISBN : 9780309683494
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
