Adaptive Optics for Biological Imaging


Book Description

Adaptive Optics for Biological Imaging brings together groundbreaking research on the use of adaptive optics for biological imaging. The book builds on prior work in astronomy and vision science. Featuring contributions by leaders in this emerging field, it takes an interdisciplinary approach that makes the subject accessible to nonspecialists who want to use adaptive optics techniques in their own work in biology and bioengineering. Organized into three parts, the book covers principles, methods, and applications of adaptive optics for biological imaging, providing the reader with the following benefits: Gives a general overview of applied optics, including definitions and vocabulary, to lay a foundation for clearer communication across disciplines Explains what kinds of optical aberrations arise in imaging through various biological tissues, and what technology can be used to correct for these aberrations Explores research done with a variety of biological samples and imaging instruments, including wide-field, confocal, and two-photon microscopes Discusses both indirect wavefront sensing, which uses an iterative approach, and direct wavefront sensing, which uses a parallel approach Since the sample is an integral part of the optical system in biological imaging, the field will benefit from participation by biologists and biomedical researchers with expertise in applied optics. This book helps lower the barriers to entry for these researchers. It also guides readers in selecting the approach that works best for their own applications.




Handbook of Adaptive Optics


Book Description

Adaptive Optics (AO) is a technique allowing the manipulation of the wavefront of the light benefitting multiple fields like Microscopy, Optical Coherence Tomography, Visual Testing, Optical Communications, and Astronomical Optics, just to mention some examples. Handbook of Adaptive Optics contains a complete picture of the technique from the foundations to the most promising applications of AO in a variety of fields. Within this book, the reader will find different sections, including: a complete and rigorous introduction to the foundation of the technique from a general perspective, providing the reader a solid basis in AO with particular emphasis on wavefront sensing methods and aberration correctors. It also discusses state-of-the-art applications and industrial usages with their particular constraints and methods to incorporate AO, like in some imaging techniques of importance for Biomedical Optics, in Astronomy and for Visual Optics. Furthermore, it explores discussions of the future of AO together with some of the most exciting emerging applications, including quantum technologies, scattering correction, space telescopes, and discrete AO, among others. This timely handbook will be an important companion to those starting in the field, but it will also serve as a comprehensive resource for researchers and experts who are already working with AO.







Wavefront Shaping for Biomedical Imaging


Book Description

Learn about the theory, techniques and applications of wavefront shaping in biomedical imaging using this unique text. With authoritative contributions from researchers who are defining the field, cutting-edge theory is combined with real-world practical examples, experimental data and the latest research trends to provide the first book-level treatment of the subject. It is suitable for both background reading and use in a course, with coverage of essential topics such as adaptive optical microscopy, deep tissue microscopy, time reversal and optical phase conjugation, and tomography. The latest images from the forefront of biomedical imaging are included, and full-colour versions are available in the eBook version. Researchers, practitioners and graduate students in optics, biophotonics, biomedical engineering, and biology who use biomedical imaging tools and are looking to advance their knowledge of the subject will find this an indispensable resource.




High Resolution Imaging in Microscopy and Ophthalmology


Book Description

This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.




Adaptive Optics for Industry and Medicine


Book Description

This proceedings volume presents the very latest developments in non-astronomical adaptive optics. This international workshop, the sixth in a biennial series, was the largest ever held and boasted significant involvement by industry. Adaptive optics is on the verge of being used in many products; indeed, at this meeting, the use of adaptive optics in DVD players was disclosed for the first time. Sample Chapter(s). Liquid Crystal Lenses For Correction Of Presbyopia (586 KB). Contents: Wavefront Correctors and Control: Liquid Crystal Lenses for Correction of Presbyopia (G Li & N Peyghambarian); Woofer-Tweeter Adaptive Optics (T Farrell & C Dainty); Wavefront Sensors: A Fundamental Limit for Wavefront Sensing (C Paterson); Direct Diffractive Image Simulation (A P Maryasov et al.); Adaptive Optics in Vision Science: A Study of Field Aberrations in the Human Eye (A V Goncharov et al.); Characterization of an AO-OCT System (J W Evans et al.); Adaptive Optics in Optical Storage and Microscopy: Commercialization of the Adaptive Scanning Optical Microscope (ASOM) (B Potsaid et al.); Towards Four Dimensional Particle Tracking for Biological Applications (H I Campbell et al.); Adaptive Optics in Lasers: New Results in High Power Lasers Beam Correction (A Kudryashov et al.); Adaptive Optics Control of Solid-State Lasers (W Lubeigt et al.); Adaptive Optics in Communication and Atmospheric Compensation: Fourier Image Sharpness Sensor for Laser Communications (K N Walker & R K Tyson); Adaptive Optics System for a Small Telescope (G Vdovin et al.); and other papers. Readership: Industry- and university-level researchers in optics and laser physics.




Computational Optical Phase Imaging


Book Description

In this book, computational optical phase imaging techniques are presented along with Matlab codes that allow the reader to run their own simulations and gain a thorough understanding of the current state-of-the-art. The book focuses on modern applications of computational optical phase imaging in engineering measurements and biomedical imaging. Additionally, it discusses the future of computational optical phase imaging, especially in terms of system miniaturization and deep learning-based phase retrieval.




Advanced Optical Methods for Brain Imaging


Book Description

This book highlights the rapidly developing field of advanced optical methods for structural and functional brain imaging. As is known, the brain is the most poorly understood organ of a living body. It is indeed the most complex structure in the known universe and, thus, mapping of the brain has become one of the most exciting frontlines of contemporary research. Starting from the fundamentals of the brain, neurons and synapses, this book presents a streamlined and focused coverage of the core principles, theoretical and experimental approaches, and state-of-the-art applications of most of the currently used imaging methods in brain research. It presents contributions from international leaders on different photonics-based brain imaging modalities and techniques. Included are comprehensive descriptions of many of the technology driven spectacular advances made over the past few years that have allowed novel insights of the structural and functional details of neurons. The book is targeted at researchers, engineers and scientists who are working in the field of brain imaging, neuroscience and connectomics. Although this book is not intended to serve as a textbook, it will appeal to undergraduate students engaged in the specialization of brain imaging.




Fluorescence Microscopy


Book Description

Fluorescence Microscopy: Super-Resolution and other Novel Techniques delivers a comprehensive review of current advances in fluorescence microscopy methods as applied to biological and biomedical science. With contributions selected for clarity, utility, and reproducibility, the work provides practical tools for investigating these ground-breaking developments. Emphasizing super-resolution techniques, light sheet microscopy, sample preparation, new labels, and analysis techniques, this work keeps pace with the innovative technical advances that are increasingly vital to biological and biomedical researchers. With its extensive graphics, inter-method comparisons, and tricks and approaches not revealed in primary publications, Fluorescence Microscopy encourages readers to both understand these methods, and to adapt them to other systems. It also offers instruction on the best visualization to derive quantitative information about cell biological structure and function, delivering crucial guidance on best practices in related laboratory research. - Presents a timely and comprehensive review of novel techniques in fluorescence imaging as applied to biological and biomedical research - Offers insight into common challenges in implementing techniques, as well as effective solutions