Author : Panos Macheras
Publisher : Springer Science & Business Media
Page : 446 pages
File Size : 15,96 MB
Release : 2006-04-26
Category : Mathematics
ISBN : 0387319107
This book presents a novel modeling approach to biopharamceutics, pharmacokinetics and pharmacodynamic phenomena. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. Throughout, many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.
Author : Hannah Batchelor
Publisher : John Wiley & Sons
Page : 324 pages
File Size : 32,52 MB
Release : 2021-12-20
Category : Medical
ISBN : 1119678285
Explore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.
Author : Mr. Nagineni Sudarshan Rao
Publisher : JEC PUBLICATION
Page : 291 pages
File Size : 23,66 MB
Release :
Category : Medical
ISBN : 9358506393
Welcome to the world of Advanced Biopharmaceutics & Pharmacokinetics, a field that lies at the intersection of pharmaceutical science, medicine, and technology. This book represents an exploration into the intricate mechanisms governing the fate of drugs in the human body, the evolving landscape of drug delivery systems, and the cutting-edge methodologies shaping the future of pharmacokinetics. In the ever-evolving landscape of pharmaceuticals, the quest for optimizing drug delivery, enhancing therapeutic efficacy, and minimizing adverse effects has become increasingly complex. This book seeks to unravel these complexities by delving into the advanced principles of biopharmaceutics and pharmacokinetics, providing a comprehensive guide for researchers, practitioners, and students in the pharmaceutical sciences. The journey into Advanced Biopharmaceutics & Pharmacokinetics begins with a thorough examination of the fundamental concepts that underpin drug absorption, distribution, metabolism, and excretion. From there, we navigate through the intricacies of drug formulation and delivery systems, exploring the latest innovations in nanomedicine, biosimilars, and targeted drug delivery. Throughout the chapters, we highlight the pivotal role of pharmacokinetics in drug development, emphasizing its importance in optimizing dosage regimens, understanding drug interactions, and individualizing therapies in the era of precision medicine. The integration of advanced technologies, such as systems pharmacology and therapeutic drug monitoring, further enriches the discussion, offering a glimpse into the future of pharmacokinetic research.
Author :
Publisher : Academic Press
Page : 754 pages
File Size : 26,92 MB
Release : 2021-07-07
Category : Medical
ISBN : 0128144262
Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. - Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences - Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics - Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology
Author : Alan Talevi
Publisher : Springer Nature
Page : 1209 pages
File Size : 44,34 MB
Release : 2022-06-14
Category : Medical
ISBN : 3030848604
The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties
Author : Leon Shargel
Publisher : McGraw-Hill/Appleton & Lange
Page : 625 pages
File Size : 33,41 MB
Release : 1993
Category : Biopharmaceutics
ISBN : 9780838502396
Author : Dr. Ruchi Jain, Mrs. Pooja Anand Mundada, Mr. Vedant Kumar Prajapati, Dr. Sandeep Ashok Marathe, Dr. S B Thirumalesh Naik
Publisher : Shashwat Publication
Page : 360 pages
File Size : 35,34 MB
Release : 2024-09-26
Category : Medical
ISBN : 9360872520
Preface The titled book is “A Textbook of ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS (MPH 202T)” (As per PCI regulation). The idea of book originated by authors to convey a combined database for easy understanding of ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS. This book is intended to communicate information on novel drug delivery techniques, to direct tutors and learners regarding fundamental concepts in Pharmacology II. The major aim to write this textbook is to provide information in articulate summarized manner to accomplish necessities of undergraduates as per PCI regulation. This volume is designed not only according to curriculum of undergraduate courses in pharmacy by PCI but also to communicate knowledge on ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS for post graduate learners. We assured this book will be originated very valuable by graduates, post graduates, professors and industrial learners. However any suggestion for further improvement of text are welcome and will be taken due note of.
Author : Bernd Meibohm
Publisher : John Wiley & Sons
Page : 426 pages
File Size : 44,48 MB
Release : 2006-12-13
Category : Science
ISBN : 3527609520
This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim. The result is vital reading for all pharmaceutical researchers.
Author : Sunil S. Jambhekar
Publisher :
Page : 0 pages
File Size : 15,97 MB
Release : 2023-04
Category :
ISBN : 9780857114471
Author : Rakesh Kumar Tekade
Publisher : Academic Press
Page : 816 pages
File Size : 24,77 MB
Release : 2022-02-05
Category : Medical
ISBN : 0323913164
Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists. - Allows readers to systematically integrate up-to-date research findings into their laboratory work - Presents focused explorations of bioanalytical methods for bioavailability and bioequivalence assessment - Provides clinical applications of concepts
