Advanced Manufacturing


Book Description

How to rethink innovation and revitalize America's declining manufacturing sector by encouraging advanced manufacturing, bringing innovative technologies into the production process. The United States lost almost one-third of its manufacturing jobs between 2000 and 2010. As higher-paying manufacturing jobs are replaced by lower-paying service jobs, income inequality has been approaching third world levels. In particular, between 1990 and 2013, the median income of men without high school diplomas fell by an astonishing 20% between 1990 and 2013, and that of men with high school diplomas or some college fell by a painful 13%. Innovation has been left largely to software and IT startups, and increasingly U.S. firms operate on a system of “innovate here/produce there,” leaving the manufacturing sector behind. In this book, William Bonvillian and Peter Singer explore how to rethink innovation and revitalize America's declining manufacturing sector. They argue that advanced manufacturing, which employs such innovative technologies as 3-D printing, advanced material, photonics, and robotics in the production process, is the key. Bonvillian and Singer discuss transformative new production paradigms that could drive up efficiency and drive down costs, describe the new processes and business models that must accompany them, and explore alternative funding methods for startups that must manufacture. They examine the varied attitudes of mainstream economics toward manufacturing, the post-Great Recession policy focus on advanced manufacturing, and lessons from the new advanced manufacturing institutes. They consider the problem of “startup scaleup,” possible new models for training workers, and the role of manufacturing in addressing “secular stagnation” in innovation, growth, the middle classes, productivity rates, and related investment. As recent political turmoil shows, the stakes could not be higher.




The Next Production Revolution Implications for Governments and Business


Book Description

This publication examines the opportunities and challenges, for business and government, associated with technologies bringing about the “next production revolution”. These include a variety of digital technologies (e.g. the Internet of Things and advanced robotics), industrial...




From Additive Manufacturing to 3D/4D Printing 3


Book Description

With a turnover of some 5-15 billion € / year, the additive manufacturing has industrial niches bearers thanks to processes and materials more and more optimized. While some niches still exist on the application of additive techniques in traditional fields (from jewelery to food for example), several trends emerge, using new concepts: collective production, realization of objects at once (without addition Of material), micro-fluidic, 4D printing exploiting programmable materials and materials, bio-printing, etc. There are both opportunities for new markets, promises not envisaged less than 10 years ago, but difficulties in reaching them.




Information in Contemporary Society


Book Description

This book constitutes the proceedings of the 14th International Conference on Information in Contemporary Society, iConference 2019, held in Washington, DC, USA, in March/April 2019. The 44 full papers and 33 short papers presented in this volume were carefully reviewed and selected from 133 submitted full papers and 88 submitted short papers. The papers are organized in the following topical sections: Scientific work and data practices; methodological concerns in (big) data research; concerns about “smart” interactions and privacy; identity questions in online communities; measuring and tracking scientific literature; limits and affordances of automation; collecting data about vulnerable populations; supporting communities through public libraries and infrastructure; information behaviors in academic environments; data-driven storytelling and modeling; online activism; digital libraries, curation and preservation; social-media text mining and sentiment analysis; data and information in the public sphere; engaging with multi-media content; understanding online behaviors and experiences; algorithms at work; innovation and professionalization in technology communities; information behaviors on Twitter; data mining and NLP; informing technology design through offline experiences; digital tools for health management; environmental and visual literacy; and addressing social problems in iSchool research.




Double Jeopardy


Book Description

Making the case that we can use nuclear power to combat climate change even as we reduce the risks of nuclear terror. Humanity faces two existential threats: nuclear annihilation and catastrophic climate change. Both have human origins, and both are linked to the use of nuclear energy. Inherent in the use of atomic fission is the risk that the technology and materials can be diverted to terrorists or hostile nations and used to make nuclear weapons. The key question is whether we can use nuclear energy to reduce the threat of climate change without increasing the risk that nuclear weapons will be used. In Double Jeopardy, Daniel Poneman argues that the world needs an “all-of-the-above” energy policy, one that advances the goal of decarbonizing the environment through all available means—including nuclear power. Poneman makes a compelling case that we can enhance the ability of nuclear power to combat climate change even as we reduce the risks of nuclear terror. Doing so will require well-crafted laws and policies, implemented with an ethos of constant vigilance and embedded in a culture that weaves safety and security goals into the fabric of our nuclear programs. This will enable government and industry to work together to maximize energy and climate benefits while minimizing safety and security risks.




Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2018: Role of facilities and administrative costs in supporting NIH-funded research; Down Syndrome: update on the state of the science and potential discoveries across other major diseases


Book Description




How the Internet of Things is Changing Our Colleges, Our Classrooms, and Our Students


Book Description

You have heard about the Internet of Things. You know that it is having an impact on higher education. So, what is it? Now that students have the entire computing power of 1975 in a pocket device, the college of the 2020s is entering a new educational age. For teens and tweens, the magic world of Harry Potter is all around. With a wave of a hand, they can control lights and surround themselves with music. In minutes, they can make a catalog of devices appear using a 3D printer. And now, they are ready to travel by driverless cars, summoned from a cellphone. Embedded technology, that is, computing built into everyday devices, is all around. Known as the Internet of Things, embedded sensors in our home, in our tools, and even in our baseball bats have changed the world as we know it. As with every stage of evolution, leaders have the options to resist, adapt, or to get ahead of the change.




Specification of Drug Substances and Products


Book Description

Specification of Drug Substances and Products: Development and Validation of Analytical Methods, Second Edition, presents a comprehensive and critical analysis of the requirements and approaches to setting specifications for new pharmaceutical products, with an emphasis on phase-appropriate development, validation of analytical methods, and their application in practice. This thoroughly revised second edition covers topics not covered or not substantially covered in the first edition, including method development and validation in the clinical phase, method transfer, process analytical technology, analytical life cycle management, special challenges with generic drugs, genotoxic impurities, topical products, nasal sprays and inhalation products, and biotechnology products. The book's authors have been carefully selected as former members of the ICH Expert Working Groups charged with developing the ICH guidelines, and/or subject-matter experts in the industry, academia and in government laboratories. - Presents a critical assessment of the application of ICH guidelines on method validation and specification setting - Written by subject-matter experts involved in the development and application of the guidelines - Provides a comprehensive treatment of the analytical methodologies used in the analysis, control and specification of new drug substances and products - Covers the latest statistical approaches (including analytical quality by design) in the development of specifications, method validation and shelf-life prediction




The Next Production Revolution


Book Description

This publication examines the opportunities and challenges, for business and government, associated with technologies bringing about the “next production revolution”. These include a variety of digital technologies (e.g. the Internet of Things and advanced robotics), industrial biotechnology, 3D printing, new materials and nanotechnology. Some of these technologies are already used in production, while others will be available in the near future. All are developing rapidly. As these technologies transform the production and the distribution of goods and services, they will have far-reaching consequences for productivity, skills, income distribution, well-being and the environment. The more that governments and firms understand how production could develop in the near future, the better placed they will be to address the risks and reap the benefits.




Production in the Innovation Economy


Book Description

Reports from an ambitious MIT research project that makes the case for encouraging the colocation of manufacturing and innovation. Production in the Innovation Economy emerges from several years of interdisciplinary research at MIT on the links between manufacturing and innovation in the United States and the world economy. Authors from political science, economics, business, employment and operations research, aeronautics and astronautics, and nuclear engineering come together to explore the extent to which manufacturing is key to an innovative and vibrant economy. Chapters include survey research on gaps in worker skill development and training; discussions of coproduction with Chinese firms and participation in complex manufacturing projects in China; analyses of constraints facing American start-up firms involved in manufacturing; proposals for a future of distributed manufacturing and a focus on product variety as a marker of innovation; and forecasts of powerful advanced manufacturing technologies on the horizon. The chapters show that although the global distribution of manufacturing is not an automatic loss for the United States, gains from the colocation of manufacturing and innovation have not disappeared. The book emphasizes public policy that encourages colocation through, for example, training programs, supplements to private capital, and interfirm cooperation in industry consortia. Such approaches can help the United States not only to maintain manufacturing capacity but also, crucially, to maximize its innovative potential. Contributors Joyce Lawrence, Richard K. Lester, Richard M. Locke, Florian Metzler, Jonas Nahm, Paul Osterman, Elisabeth B. Reynolds, Donald B. Rosenfeld, Hiram M. Samel, Sanjay E. Sarma, Edward S. Steinfeld, Andrew Weaver, Rachel L. Wellhausen, Olivier de Weck