Systemic Approaches in Bioinformatics and Computational Systems Biology


Book Description

"This book presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data, covering three subject areas: bioinformatics, computational biology, and computational systems biology"--




Advances in Morphometrics


Book Description

This volume is based on the NATO Advanced Study Institute, "Advances in Mor phometries" held in 11 Ciocco, Tuscany, Italy from July 18-30, 1993, and directed by Leslie F. Marcus. The "Advances in Morphometries" ASI was advertised in Nature and a number of professional journals. Announcements were sent to relevant institutions and departments throughout the world. Because NATO required that the majority of attendees be from NATO countries, the 71 persons attending represented nine NATO countries, four eastern European countries, now recognized as equal partners for AS Is, and a few participants from non-NATO countries. Participants were all active scholars in different disciplines within biology, as well as computer science, statistics, geology and paleontology. Their experience ranged from that of graduate students to senior faculty, as well as one emeritus scholar. A complete list of the those attending and their addresses, phone and FAX numbers and, where available, e-mail addresses is given in the participants list. All the local arrangements were made by Marco Corti and Anna Loy of the University of Rome "Ia Sapienza. " They made the initial contact with the II Ciocco conference center and then arranged for computer and Xerox rentals, design of logos, organization of posters, and publication of poster abstracts.




Computational Methods in Systems Biology


Book Description

This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology, CMSB 2008, held in Rostock, Germany, in September 2008. The 21 revised full papers presented together with the summaries of 5 invited papers were carefully reviewed and selected from more than 60 submissions. The papers cover theoretical or applied contributions that are motivated by a biological question focusing on modeling approaches, including process algebra, simulation approaches, analysis methods, in particular model checking and flux analysis, and case studies.




Memory Practices in the Sciences


Book Description

How the way we hold knowledge about the past—in books, in file folders, in databases—affects the kind of stories we tell about the past. The way we record knowledge, and the web of technical, formal, and social practices that surrounds it, inevitably affects the knowledge that we record. The ways we hold knowledge about the past—in handwritten manuscripts, in printed books, in file folders, in databases—shape the kind of stories we tell about that past. In this lively and erudite look at the relation of our information infrastructures to our information, Geoffrey Bowker examines how, over the past two hundred years, information technology has converged with the nature and production of scientific knowledge. His story weaves a path between the social and political work of creating an explicit, indexical memory for science—the making of infrastructures—and the variety of ways we continually reconfigure, lose, and regain the past. At a time when memory is so cheap and its recording is so protean, Bowker reminds us of the centrality of what and how we choose to forget. In Memory Practices in the Sciences he looks at three "memory epochs" of the nineteenth, twentieth, and twenty-first centuries and their particular reconstructions and reconfigurations of scientific knowledge. The nineteenth century's central science, geology, mapped both the social and the natural world into a single time package (despite apparent discontinuities), as, in a different way, did mid-twentieth-century cybernetics. Both, Bowker argues, packaged time in ways indexed by their information technologies to permit traffic between the social and natural worlds. Today's sciences of biodiversity, meanwhile, "database the world" in a way that excludes certain spaces, entities, and times. We use the tools of the present to look at the past, says Bowker; we project onto nature our modes of organizing our own affairs.




Analysis of Phylogenetics and Evolution with R


Book Description

This book integrates a wide variety of data analysis methods into a single and flexible interface: the R language. The book starts with a presentation of different R packages and gives a short introduction to R for phylogeneticists unfamiliar with this language. The basic phylogenetic topics are covered. The chapter on tree drawing uses R's powerful graphical environment. A section deals with the analysis of diversification with phylogenies, one of the author's favorite research topics. The last chapter is devoted to the development of phylogenetic methods with R and interfaces with other languages (C and C++). Some exercises conclude these chapters.




Describing Species


Book Description

A basic practical manual for the process of describing new species, this desperately needed desk reference and guide to nomenclatural procedure and taxonomic writing serves as a Strunk & White of species description, covering both botanical and zoological codes of nomenclature.




Advances in Systems Biology


Book Description

The International Society for Systems Biology (ISSB) is a society aimed at advancing world-wide systems biology research by providing a forum for scientific discussions and various academic services. The ISSB helps coordinate researchers to form alliances for meeting the unique needs of multidisciplinary and international systems biology research. The annual International Conference on Systems Biology (ICSB) serves as the main meeting for the society and is one of the largest academic and commercial gatherings under the broad heading of ‘Systems Biology’.




Elements of Computational Systems Biology


Book Description

Groundbreaking, long-ranging research in this emergent field that enables solutions to complex biological problems Computational systems biology is an emerging discipline that is evolving quickly due to recent advances in biology such as genome sequencing, high-throughput technologies, and the recent development of sophisticated computational methodologies. Elements of Computational Systems Biology is a comprehensive reference covering the computational frameworks and techniques needed to help research scientists and professionals in computer science, biology, chemistry, pharmaceutical science, and physics solve complex biological problems. Written by leading experts in the field, this practical resource gives detailed descriptions of core subjects, including biological network modeling, analysis, and inference; presents a measured introduction to foundational topics like genomics; and describes state-of-the-art software tools for systems biology. Offers a coordinated integrated systems view of defining and applying computational and mathematical tools and methods to solving problems in systems biology Chapters provide a multidisciplinary approach and range from analysis, modeling, prediction, reasoning, inference, and exploration of biological systems to the implications of computational systems biology on drug design and medicine Helps reduce the gap between mathematics and biology by presenting chapters on mathematical models of biological systems Establishes solutions in computer science, biology, chemistry, and physics by presenting an in-depth description of computational methodologies for systems biology Elements of Computational Systems Biology is intended for academic/industry researchers and scientists in computer science, biology, mathematics, chemistry, physics, biotechnology, and pharmaceutical science. It is also accessible to undergraduate and graduate students in machine learning, data mining, bioinformatics, computational biology, and systems biology courses.




ADVANCED GEOGRAPHIC INFORMATION SYSTEMS -Volume I


Book Description

Advanced Geographic Information Systems is a component of Encyclopedia of Earth and Atmospheric Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The content of the Theme on Advanced Geographic Information Systems is organized with state-oc-the-art presentations covering the following aspects of the subject: Spatio-Temporal Information Systems; Interacting with GIS - From Paper Cartography to Virtual Environments; Spatial Data Management: Topic Overview; Introduction to Spatial Decision Support Systems; GIS Interoperability, from Problems to Solutions. These volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.




Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances


Book Description

The convergence of biology and computer science was initially motivated by the need to organize and process a growing number of biological observations resulting from rapid advances in experimental techniques. Today, however, close collaboration between biologists, biochemists, medical researchers, and computer scientists has also generated remarkable benefits for the field of computer science. Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data. The book covers three subject areas: bioinformatics, computational biology, and computational systems biology. It focuses on recent, systemic approaches in computer science and mathematics that have been used to model, simulate, and more generally, experiment with biological phenomena at any scale.