Aluminium Toxicity In Infants' Health And Disease


Book Description

Aluminium is the most abundant metal ion in the biosphere and we are continuously exposed to it in our everyday life through food, beverages, pharmaceutical products, etc. This book is a current and comprehensive review of the biochemistry, metabolism and toxicity of aluminium undertaken by an international group of authors, many of whom are outstanding authorities in their respective fields. In contrast with previous books on this topic, much of the subject matter is unique, in that it is primarily directed at aluminium nutrition and toxicity in infants and children. This book covers many aspects of aluminium toxicity in infants including for instance the embryo-fetal as well as the neurodevelopmental effects of this element, contamination of pharmaceutical products, and individual sensitivity through vaccines using aluminium as an adjuvant.This book will be especially useful to paediatricians, paediatric nephrologists & neurologists, nutritionists, toxicologists, biochemical toxicologists and postgraduate students.




Infant Formula


Book Description

Infant formulas are unique because they are the only source of nutrition for many infants during the first 4 to 6 months of life. They are critical to infant health since they must safely support growth and development during a period when the consequences on inadequate nutrition are most severe. Existing guidelines and regulations for evaluating the safety of conventional food ingredients (e.g., vitamins and minerals) added to infant formulas have worked well in the past; however they are not sufficient to address the diversity of potential new ingredients proposed by manufacturers to develop formulas that mimic the perceived and potential benefits of human milk. This book, prepared at the request of the Food and Drug Administration (FDA) and Health Canada, addresses the regulatory and research issues that are critical in assessing the safety of the addition of new ingredients to infants.




Toxicological Profile for Aluminum (Update)


Book Description

This report provides information about aluminum and the human health effects of exposure. This chemical has been found in many sites identified by the EPA for long-term Federal cleanup activities. The report includes a Public Health Statement which explains the toxicologic properties of aluminum in a nontechnical, Q&A format, and a review of the general health effects observed following exposure; a description of health effects; how the chemical can affect children; and information on its chemical and physical properties, production, use and disposal, potential for human exposure, analytical methods, and regulations and advisories.




The Vaccine-Friendly Plan


Book Description

An accessible and reassuring guide to childhood health and immunity from a pediatrician who’s both knowledgeable about the latest scientific research and respectful of a family’s risk factors, health history, and concerns In The Vaccine-Friendly Plan, Paul Thomas, M.D., presents his proven approach to building immunity: a new protocol that limits a child’s exposure to aluminum, mercury, and other neurotoxins while building overall good health. Based on the results from his pediatric practice of more than eleven thousand children, as well as data from other credible and scientifically minded medical doctors, Dr. Paul’s vaccine-friendly protocol gives readers • recommendations for a healthy pregnancy and childbirth • vital information about what to expect at every well child visit from birth through adolescence • a slower, evidence-based vaccine schedule that calls for only one aluminum-containing shot at a time • important questions to ask about your child’s first few weeks, first years, and beyond • advice about how to talk to health care providers when you have concerns • the risks associated with opting out of vaccinations • a practical approach to common illnesses throughout the school years • simple tips and tricks for healthy eating and toxin-free living at any age The Vaccine-Friendly Plan presents a new standard for pediatric care, giving parents peace of mind in raising happy, healthy children. Praise for The Vaccine-Friendly Plan “Finally, a book about vaccines that respects parents! If you choose only one book to read on the topic, read The Vaccine-Friendly Plan. This impeccably researched, well-balanced book puts you in the driver’s seat and empowers you to make conscientious vaccine decisions for your family.”—Peggy O’Mara, editor and publisher, Mothering Magazine “Sure to appeal to readers of all kinds as a friendly, no-nonsense book that cuts through the rhetoric surrounding vaccines. It offers validation to those who avoid some or all, while offering those who do want to vaccinate help on how to do so safely. This is a great book for anyone with children in their lives.”—Natural Mother “A valuable, science-supported guide to optimizing your child’s health while you navigate through complex choices in a toxic, challenging world.”—Martha Herbert, M.D., Ph.D., Harvard Medical School “An impressively researched guide, this important book is essential reading for parents. With clear and practical advice for shielding children from harmful toxins, it will compel us all to think differently about how to protect health.”—Jay Gordon, M.D., FAAP “Rather than a one-size-fits-all vaccine strategy, the authors suggest thoughtful, individualized decisions based on research and collaboration between parents and clinicians—a plan to optimize a child’s immune system and minimize any risks.”—Elizabeth Mumper, M.D., founder and CEO, The Rimland Center for Integrative Pediatrics “This well-written and thought-provoking book will encourage parents to think through decisions—such as food choices and the timing of vaccines—that affect the well-being of their children. In a world where children’s immune systems are increasingly challenged, this is a timely addition to the literature.”—Harriet Lerner, Ph.D., bestselling author of The Dance of Anger and The Mother Dance




Aluminium and Alzheimer's Disease


Book Description

The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to impact upon mammalian physiology and function and range from clinical studies, through animal models of disease to the detailed biochemistry of aluminium toxicity. Chapters are also included on epidemiology and other factors involved in the aetiology of Alzheimer's.This is the first time that this subject has been treated in such a comprehensive manner. The research detailed in each chapter, includes the latest research in the field, it has been critically appraised and this appraisal has been used by each author to present an informed opinion of its relevance to aluminium and Alzheimer's disease. The chapters are much more than reviews; they are a statement of the state of the art and of what the future may hold for research in this field. As a whole they show the high quality of research that has been carried out in our efforts to understand the toxicity of aluminium in man and that we are far away from discounting the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease.




The Childhood Immunization Schedule and Safety


Book Description

Vaccines are among the most safe and effective public health interventions to prevent serious disease and death. Because of the success of vaccines, most Americans today have no firsthand experience with such devastating illnesses as polio or diphtheria. Health care providers who vaccinate young children follow a schedule prepared by the U.S. Advisory Committee on Immunization Practices. Under the current schedule, children younger than six may receive as many as 24 immunizations by their second birthday. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some risk. Driven largely by concerns about potential side effects, there has been a shift in some parents' attitudes toward the child immunization schedule. The Childhood Immunization Schedule and Safety identifies research approaches, methodologies, and study designs that could address questions about the safety of the current schedule. This report is the most comprehensive examination of the immunization schedule to date. The IOM authoring committee uncovered no evidence of major safety concerns associated with adherence to the childhood immunization schedule. Should signals arise that there may be need for investigation, however, the report offers a framework for conducting safety research using existing or new data collection systems.




Vax Facts


Book Description

Vax Facts is a one-stop-shop for all the information parents and guardians need to make an informed choice about childhood vaccinations. The challenge for most who are wrestling with whether to give a vaccine is a lack of understanding about what information they really need to make an informed decision. Written by a pediatrician who witnessed the difference over decades in the health outcomes of the vaccinated, partially vaccinated, and unvaccinated children in his practice, Vax Facts will enlighten parents and guardians and provide the information needed for informed consent. Covering each of the vaccines recommended by the CDC and doctors, from pregnancy through the teen years, this detailed guide breaks down the ingredients, the lack of safety testing, and the side effects and risks of the vaccines. With the help of simple data tables that compare the rates of death from the diseases for which we have vaccines and the rates of death from the vaccines themselves, parents and guardians can easily decide what’s right for their children. With almost four million births per year in the United States, this useful resource will resonate with all who are pregnant or considering pregnancy, and all parents, grandparents, aunts, and uncles who are considering whether vaccination is appropriate for a family member or loved one. At the end of each chapter, Just a Mom (coauthor DeeDee Hoover) shares personal stories and reflections that allow readers to connect with the information. This information-packed guide is for all those asking “Should I get my child vaccinated?” who want more than just a yes/no answer. After reading Vax Facts, parents and guardians will be able to decide with confidence whether vaccination is the right choice for their loved one.




Toxicological Risks of Selected Flame-Retardant Chemicals


Book Description

Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.




Food Additive


Book Description

A food additive is defined as a substance not normally consumed as a food in itself and not normally used as a characteristic ingredient of food whether or not it has nutritive value. Food additives are natural or manufactured substances, which are added to food to restore colors lost during processing. They provide sweetness, prevent deterioration during storage and guard against food poisoning (preservatives). This book provides a review of traditional and non-traditional food preservation approaches and ingredients used as food additives. It also provides detailed knowledge for the evaluation of the agro-industrial wastes based on their great potential for the production of industrially relevant food additives. Furthermore the assessment of potential reproductive and developmental toxicity perspectives of some newly synthesized food additives on market has been covered. Finally, the identification of the areas relevant for future research has been pointed out indicating that there is more and more information needed to explore the possibility of the implementation of some other materials to be used as food additives.




Diet and Health


Book Description

Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.